ID   A0A1J6KYH5_NICAT        Unreviewed;      1116 AA.
AC   A0A1J6KYH5;
DT   15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT   15-FEB-2017, sequence version 1.
DT   24-JAN-2024, entry version 25.
DE   RecName: Full=PX domain-containing protein {ECO:0000259|PROSITE:PS50195};
GN   ORFNames=A4A49_28771 {ECO:0000313|EMBL:OIT24097.1};
OS   Nicotiana attenuata (Coyote tobacco).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae;
OC   Nicotiana.
OX   NCBI_TaxID=49451 {ECO:0000313|EMBL:OIT24097.1, ECO:0000313|Proteomes:UP000187609};
RN   [1] {ECO:0000313|EMBL:OIT24097.1, ECO:0000313|Proteomes:UP000187609}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. UT {ECO:0000313|Proteomes:UP000187609};
RC   TISSUE=Leaves {ECO:0000313|EMBL:OIT24097.1};
RA   Xu S., Brockmoeller T., Gaquerel E., Navarro A., Kuhl H., Gase K., Ling Z.,
RA   Zhou W., Kreitzer C., Stanke M., Tang H., Lyons E., Pandey P., Pandey S.P.,
RA   Timmermann B., Baldwin I.T.;
RT   "The genome of Nicotiana attenuata.";
RL   Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OIT24097.1}.
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DR   EMBL; MJEQ01003218; OIT24097.1; -; Genomic_DNA.
DR   RefSeq; XP_019236100.1; XM_019380555.1.
DR   AlphaFoldDB; A0A1J6KYH5; -.
DR   STRING; 49451.A0A1J6KYH5; -.
DR   EnsemblPlants; OIT24097; OIT24097; A4A49_28771.
DR   GeneID; 109216407; -.
DR   Gramene; OIT24097; OIT24097; A4A49_28771.
DR   KEGG; nau:109216407; -.
DR   OMA; WDFTQYP; -.
DR   OrthoDB; 126314at2759; -.
DR   Proteomes; UP000187609; Unassembled WGS sequence.
DR   GO; GO:0005768; C:endosome; IEA:UniProt.
DR   GO; GO:0016020; C:membrane; IEA:UniProt.
DR   GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR   CDD; cd06093; PX_domain; 1.
DR   Gene3D; 3.30.1520.10; Phox-like domain; 1.
DR   InterPro; IPR001683; PX_dom.
DR   InterPro; IPR036871; PX_dom_sf.
DR   InterPro; IPR025258; RH_dom.
DR   PANTHER; PTHR45971; PHOX (PX) DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR45971:SF1; RUBICON, ISOFORM A; 1.
DR   Pfam; PF00787; PX; 1.
DR   Pfam; PF13901; RH_dom; 1.
DR   SMART; SM01175; DUF4206; 1.
DR   SUPFAM; SSF64268; PX domain; 1.
DR   PROSITE; PS50195; PX; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000187609}.
FT   DOMAIN          636..756
FT                   /note="PX"
FT                   /evidence="ECO:0000259|PROSITE:PS50195"
FT   REGION          229..268
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          502..545
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          755..781
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1090..1116
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        503..517
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        518..545
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1090..1104
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1116 AA;  123718 MW;  1190279706D30B07 CRC64;
     MENGEGTKEN LASAVSSPFV PLGNEFSWQS QKSEDGDDLT EYSSCDAESE FERYCSANSA
     MGTPTVGGSV VTVFHEFPGS FKLGDDSYRV KRFRGCKKLS DFSGVGPSTR GGEHSGGKGS
     AREEALVGFG KGLDLYGNAG FMDEETFLQN MDMGDEWYVK DDEMPNMRSD NGTKLRFNRS
     SCTSDEYKNG VLIEGDTEAS GVVNNSLEIE AEFQRDIEAV DGSLEVSSLQ PGAAAGGAEC
     LDESETSSRY EYSEGEDSMF GGNTDDEKND SYFRKEVKHS DEEHDKNGYK LVMGSAVAFG
     LNDWDDFMQE NGEFTPTLMV HNELQADNQP SIESENGCLS SASTVNAEFS SVGLTMPKEK
     EKGTLLPSCH GQGVNESTEH TTTYNVDPLS LLNQGKGENA EGEKAMLVKN NETRKVNESA
     EFHDKSSVHN MLQVDHNPQR QPGEASLIEG AKLKVELLEP TDQCACTEEF IHITDDLVSR
     KAEPENLRLL LDPLSRSATS KDYLSMEHSD DRTVELSADK SSSPSSASVA NDATRTKHGT
     MNSSSSVNYL EDHLTSGKTH NLELNEFYNE VVHDMEEILL DSSESPGFAL GNKIHHSYIP
     LPSRDGGSTA STSVTFDVSP DTQRPVRFDR VEVVGARQKT GDVSLSERLV GAKKYTVYRI
     KVWSGEDYWE VERRYRDFFA LYRQLKKSFA DQGWILPPVW SATERESRKI FGSASPNVVA
     DRSVLIQECL HSLLHDKFRS GPLNALICFL SPSKDVPNSP ASDTNIPQSP YSSRSTSRGD
     VSSLGKKISL IVHKRPLKSK KQLLDEQHYS CAGCYKSFDD GKTRIEELAQ TLGWGKPRLC
     EYSGQLYCSS CHTNDMAVLP ARVLHCWDFN QYPVSQLAKS YLDSIYDQPM LCVSAVNPML
     FSRVPALQHV TNIRKRIEKI LPFVRCPFRS SIYKGVGSRR YILEGNDFFA LKDLIDLSKG
     VFAALPVMVD TILRKILEHI TDQCLICYDV GIPCTARQDC DDPSSLIFPF QEGEIERCKS
     CDSVFHKHCF KRISSCPCGT RLKTEQEGSS TKGSQNMGNW GILSLDLLGK RADLSKGLVT
     GFLGKVRSLK SSRNEEEEHE DNNTVILMDS LPMTTL
//