ID A0A1J7BCM5_9ACTN Unreviewed; 422 AA.
AC A0A1J7BCM5;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=Major facilitator superfamily (MFS) profile domain-containing protein {ECO:0000259|PROSITE:PS50850};
DE Flags: Fragment;
GN ORFNames=BIV57_16750 {ECO:0000313|EMBL:OIV36341.1};
OS Mangrovactinospora gilvigrisea.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Mangrovactinospora.
OX NCBI_TaxID=1428644 {ECO:0000313|EMBL:OIV36341.1, ECO:0000313|Proteomes:UP000243342};
RN [1] {ECO:0000313|EMBL:OIV36341.1, ECO:0000313|Proteomes:UP000243342}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MUSC 26 {ECO:0000313|EMBL:OIV36341.1,
RC ECO:0000313|Proteomes:UP000243342};
RA Lee L.-H., Ser H.-L.;
RT "Genome sequence of Streptomyces gilvigriseus MUSC 26.";
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the major facilitator superfamily.
CC {ECO:0000256|ARBA:ARBA00008335}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OIV36341.1}.
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DR EMBL; MLCF01000101; OIV36341.1; -; Genomic_DNA.
DR RefSeq; WP_071657692.1; NZ_MLCF01000101.1.
DR AlphaFoldDB; A0A1J7BCM5; -.
DR STRING; 1428644.BIV57_16750; -.
DR OrthoDB; 63984at2; -.
DR Proteomes; UP000243342; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR CDD; cd17324; MFS_NepI_like; 1.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 1.
DR InterPro; IPR011701; MFS.
DR InterPro; IPR020846; MFS_dom.
DR InterPro; IPR036259; MFS_trans_sf.
DR PANTHER; PTHR43271; BLL2771 PROTEIN; 1.
DR PANTHER; PTHR43271:SF1; INNER MEMBRANE TRANSPORT PROTEIN YNFM; 1.
DR Pfam; PF07690; MFS_1; 1.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
DR PROSITE; PS50850; MFS; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000243342};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 39..55
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 75..93
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 105..124
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 130..151
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 163..182
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 194..213
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 243..260
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 272..291
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 303..322
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 328..345
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 357..379
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 399..421
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 35..422
FT /note="Major facilitator superfamily (MFS) profile"
FT /evidence="ECO:0000259|PROSITE:PS50850"
FT REGION 1..29
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..19
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 422
FT /evidence="ECO:0000313|EMBL:OIV36341.1"
SQ SEQUENCE 422 AA; 42301 MW; F3840EE633B14ACB CRC64;
MRQTRPAPAV TTALDSPSAT SVAGPFAGHR EGSPGLRRVA VALFASGLAT FALLYSTQPL
LPSLAERFRI SPGSAALSVS VTTVALGLAL LVAGPLSEVR GRTGLMKWSI IASAVIGLAV
AVAPSWPVLL VLRAVQGVAL AGLPAVAMAY LREEVHPAAH ARTTGLYVGG TAIGGMCGRL
VAGGLADLGG WRVAVAGIGV LGLLCGAAVW RLLPASRNFT PAEPRVGALL RTGGRLLRDP
GQLLLYGIAA TMMGAFVAVY NATGFRLAAG PYHLGVGAAG LVFVVYLVGS FSSTAAGRIA
DRIGRGPVIP AAAVVTAAGI ALTLCRPLPL IILGLAVMTA GFFAAHGVAS GWVPARAAAS
GIGGTGQAAS LYLFAYYLGS SVFGDLAGTA WSADAWTGVT AMTLTLTAAG AALSATAWLT
AR
//
