ID A0A1J7GCQ4_LUPAN Unreviewed; 362 AA.
AC A0A1J7GCQ4;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE RecName: Full=Vignain {ECO:0008006|Google:ProtNLM};
GN ORFNames=TanjilG_11587 {ECO:0000313|EMBL:OIV98190.1};
OS Lupinus angustifolius (Narrow-leaved blue lupine).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC genistoids sensu lato; core genistoids; Genisteae; Lupinus.
OX NCBI_TaxID=3871 {ECO:0000313|EMBL:OIV98190.1, ECO:0000313|Proteomes:UP000188354};
RN [1] {ECO:0000313|EMBL:OIV98190.1, ECO:0000313|Proteomes:UP000188354}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Tanjil {ECO:0000313|Proteomes:UP000188354};
RC TISSUE=Whole plant {ECO:0000313|EMBL:OIV98190.1};
RX PubMed=27557478; DOI=10.1111/pbi.12615;
RA Hane J.K., Ming Y., Kamphuis L.G., Nelson M.N., Garg G., Atkins C.A.,
RA Bayer P.E., Bravo A., Bringans S., Cannon S., Edwards D., Foley R.,
RA Gao L.L., Harrison M.J., Huang W., Hurgobin B., Li S., Liu C.W.,
RA McGrath A., Morahan G., Murray J., Weller J., Jian J., Singh K.B.;
RT "A comprehensive draft genome sequence for lupin (Lupinus angustifolius),
RT an emerging health food: insights into plant-microbe interactions and
RT legume evolution.";
RL Plant Biotechnol. J. 15:318-330(2017).
CC -!- SIMILARITY: Belongs to the peptidase C1 family.
CC {ECO:0000256|ARBA:ARBA00008455}.
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DR EMBL; CM007374; OIV98190.1; -; Genomic_DNA.
DR RefSeq; XP_019415138.1; XM_019559593.1.
DR AlphaFoldDB; A0A1J7GCQ4; -.
DR STRING; 3871.A0A1J7GCQ4; -.
DR EnsemblPlants; OIV98190; OIV98190; TanjilG_11587.
DR GeneID; 109326788; -.
DR Gramene; OIV98190; OIV98190; TanjilG_11587.
DR KEGG; lang:109326788; -.
DR OMA; GKCDASK; -.
DR OrthoDB; 5472443at2759; -.
DR Proteomes; UP000188354; Chromosome LG14.
DR GO; GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd02248; Peptidase_C1A; 1.
DR Gene3D; 3.90.70.10; Cysteine proteinases; 1.
DR InterPro; IPR038765; Papain-like_cys_pep_sf.
DR InterPro; IPR025661; Pept_asp_AS.
DR InterPro; IPR000169; Pept_cys_AS.
DR InterPro; IPR025660; Pept_his_AS.
DR InterPro; IPR013128; Peptidase_C1A.
DR InterPro; IPR000668; Peptidase_C1A_C.
DR InterPro; IPR039417; Peptidase_C1A_papain-like.
DR InterPro; IPR013201; Prot_inhib_I29.
DR PANTHER; PTHR12411; CYSTEINE PROTEASE FAMILY C1-RELATED; 1.
DR PANTHER; PTHR12411:SF1001; KDEL-TAILED CYSTEINE ENDOPEPTIDASE CEP1; 1.
DR Pfam; PF08246; Inhibitor_I29; 1.
DR Pfam; PF00112; Peptidase_C1; 1.
DR PRINTS; PR00705; PAPAIN.
DR SMART; SM00848; Inhibitor_I29; 1.
DR SMART; SM00645; Pept_C1; 1.
DR SUPFAM; SSF54001; Cysteine proteinases; 1.
DR PROSITE; PS00640; THIOL_PROTEASE_ASN; 1.
DR PROSITE; PS00139; THIOL_PROTEASE_CYS; 1.
DR PROSITE; PS00639; THIOL_PROTEASE_HIS; 1.
PE 3: Inferred from homology;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Protease {ECO:0000256|ARBA:ARBA00022670};
KW Reference proteome {ECO:0000313|Proteomes:UP000188354};
KW Signal {ECO:0000256|SAM:SignalP};
KW Thiol protease {ECO:0000256|ARBA:ARBA00022807}.
FT SIGNAL 1..22
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 23..362
FT /note="Vignain"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5018593252"
FT DOMAIN 40..95
FT /note="Cathepsin propeptide inhibitor"
FT /evidence="ECO:0000259|SMART:SM00848"
FT DOMAIN 128..344
FT /note="Peptidase C1A papain C-terminal"
FT /evidence="ECO:0000259|SMART:SM00645"
SQ SEQUENCE 362 AA; 40371 MW; A7216E6CFE02DF31 CRC64;
MGMKKLLWVA LSLALVFTIA ESFDLHENDL ASEESLWDLY ERWRSHHTVS RSLNEKHKRF
NVFKANVMHV HNTNKMDKPY KLKLNKFADM TNHEFRSSYA GSKINHHQMF RGRPGGNGTF
MYEKVERVPP SVDWRKKGAV TTIKDQGQCG SCWAFSTVVA VEGINQIKTK KLVPLSEQEL
IDCDNEENHG CNGGLMEYAF EFIKQKGGIT AESSYPYAAE DGTCDESKIN DLLVSIDGHE
TVPANNEDAL RKVVANQPVS VAIDAGGSDF QFYSEGVFTG DCGTDLNHGV AIVGYGTTLD
GTKYWIVRNS WGPEWGEHGY IRMQRGISEK EGLCGIAMLA SYPIKNSSTN PTGHSSSPKD
EL
//
