ID A0A1J7H1T7_LUPAN Unreviewed; 4842 AA.
AC A0A1J7H1T7;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 13-SEP-2023, entry version 28.
DE RecName: Full=UBR-type domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=TanjilG_29961 {ECO:0000313|EMBL:OIW06540.1};
OS Lupinus angustifolius (Narrow-leaved blue lupine).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC genistoids sensu lato; core genistoids; Genisteae; Lupinus.
OX NCBI_TaxID=3871 {ECO:0000313|EMBL:OIW06540.1, ECO:0000313|Proteomes:UP000188354};
RN [1] {ECO:0000313|EMBL:OIW06540.1, ECO:0000313|Proteomes:UP000188354}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Tanjil {ECO:0000313|Proteomes:UP000188354};
RC TISSUE=Whole plant {ECO:0000313|EMBL:OIW06540.1};
RX PubMed=27557478; DOI=10.1111/pbi.12615;
RA Hane J.K., Ming Y., Kamphuis L.G., Nelson M.N., Garg G., Atkins C.A.,
RA Bayer P.E., Bravo A., Bringans S., Cannon S., Edwards D., Foley R.,
RA Gao L.L., Harrison M.J., Huang W., Hurgobin B., Li S., Liu C.W.,
RA McGrath A., Morahan G., Murray J., Weller J., Jian J., Singh K.B.;
RT "A comprehensive draft genome sequence for lupin (Lupinus angustifolius),
RT an emerging health food: insights into plant-microbe interactions and
RT legume evolution.";
RL Plant Biotechnol. J. 15:318-330(2017).
CC -!- SIMILARITY: Belongs to the UBR4 family.
CC {ECO:0000256|ARBA:ARBA00009970}.
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DR EMBL; CM007368; OIW06540.1; -; Genomic_DNA.
DR STRING; 3871.A0A1J7H1T7; -.
DR EnsemblPlants; OIW06540; OIW06540; TanjilG_29961.
DR Gramene; OIW06540; OIW06540; TanjilG_29961.
DR OMA; VHRMEEH; -.
DR Proteomes; UP000188354; Chromosome LG08.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd19681; UBR-box_BIG_like; 1.
DR CDD; cd02249; ZZ; 1.
DR Gene3D; 3.30.60.90; -; 1.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR025704; E3_Ub_ligase_UBR4_C.
DR InterPro; IPR045189; UBR4-like.
DR InterPro; IPR003126; Znf_UBR.
DR InterPro; IPR000433; Znf_ZZ.
DR InterPro; IPR043145; Znf_ZZ_sf.
DR PANTHER; PTHR21725; E3 UBIQUITIN-PROTEIN LIGASE UBR4; 1.
DR PANTHER; PTHR21725:SF1; E3 UBIQUITIN-PROTEIN LIGASE UBR4; 1.
DR Pfam; PF13764; E3_UbLigase_R4; 1.
DR Pfam; PF00569; ZZ; 1.
DR SMART; SM00396; ZnF_UBR1; 1.
DR SMART; SM00291; ZnF_ZZ; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF101908; Putative isomerase YbhE; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS51157; ZF_UBR; 1.
DR PROSITE; PS01357; ZF_ZZ_1; 1.
DR PROSITE; PS50135; ZF_ZZ_2; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000188354};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00228}.
FT TRANSMEM 4818..4841
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1563..1634
FT /note="UBR-type"
FT /evidence="ECO:0000259|PROSITE:PS51157"
FT DOMAIN 2599..2658
FT /note="ZZ-type"
FT /evidence="ECO:0000259|PROSITE:PS50135"
FT ZN_FING 1563..1634
FT /note="UBR-type"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00508"
FT REGION 1526..1555
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3125..3165
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3800..3831
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1526..1541
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3125..3144
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3145..3164
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3803..3817
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 4842 AA; 540447 MW; DEB5D8B651614713 CRC64;
MAENLINLAD VLFAGATPSP EDLLQKLRSD DNVRSALNAF YSVLRRGLEV DGDILRLQSW
NLSQIQAISS FSYAIAFATR SLSVEQAEGI LVAIVQRSIE FAVSYLEKSE FDGNDLGIQN
NMIHLLEIAL VDEMDTVADM LQPTSASALV DMLPVVDAYC GKFVDDYTKC HLQGFRCSKE
EKTVDWLLKT LDSERVPPDR QRSGFNALTY CQDLNKFVFL SQHWAVIHGQ CTPRLILLCN
KLNNVRGAFH EKAVGQSFRM RLSFTLRMLK LLTTLTKDVP YVEYDVSLVR AVASYTDALS
SLFRVQFEFV DTDATIEGSF ESIVLMVVEE FLHNVQVIFG NSSATQNIQA CIIASILGSL
ESSVWRYDKS SLNLNPPLAY FPRFVEKALK LINDLKMQRH QVPLEWKDFG AELFGSSTGS
QNDSLSCLFH LESVPLGKSY TSDELLKLIF PSSSQWIDNL LQLALFLYSE GLKLMPKMER
SYSSSAKVTG TSDIENAICH EDEALFGDLF SETGRSVACT DGCEQPPAAT LISNSSYHNM
PIQAAIELLN FLKTCIFSAE WHPSLYVDGC NKLSSRHIDI LLYLLNCQGC CSEDKSFSPH
EDTKIGHIHE LCYDLFYNLL MNHALSDSLE DYLVEKILIV ENGAFCYDDR TLTLLAHTLF
CRVGSTGSQL RTKIYRGYVS FVFDMVKSVC TKCPSFKDLV GTLPSLFHIE VVLIAFHLSD
EAEKVMMVNL IFSTFKEVAN LALDLNNTQL TCWALVVSRL ILVLRHLIFH QQTCPTALLL
DVRSKLRIVS QSEPSMSNKV NDHLSSWPST ALKNLMGALV GEEVVSSLTE QLIDFSGFPV
SLGRDDLTID CLTSKWEDIY LTFSLVLGLW RGKKASAVVD LIVERYFFTL CWDIPCAGSE
EHPIISCSRD HPLDLCDMLH FSYFSHSLLG HQQLIEKFTT CPDTVLSLLQ HLSAMSMPEG
IEEFGWDFLR SGMWLSLILS FTNTGILKYF MDNEISGQGL NWTDNYFGDQ TYVELAGNMI
SSMIASGQFP LLVRLFSSLL NKYVKIHQKA FLATITSRQN QASGFLPVLL LKHTRIDKFL
QGELLERSSS NESELESCLT LLSRFDSTVD KKASGILSRT SWECMFHGFP FHLSTPSATM
FSCIVSIRGL IFALDGLLKI NEAGGNVDMD VEVLREILDA VMNIKFDKIF ENIHVKCDTI
YHSLTAELEW SDYGNLILVK QMEGFLRDIS AGGVSDGNIL EWIICQVMEI LSSLKKDPSK
SVMLNLYLGL ESVPVQINKH LELHHSDCLF LIDSLDTCCS ESVNVKVLGF FVDLVSGELF
PDLKKKIQRK FLDKDSSCLA QWLERRILGT VVDSSSGVNC ANGSSSSLRE TTINFVLCLV
SSPSEQQSKE LQNHMFESAL LALDTAFLLF DIHVARSYFN FIVQISRGES LMKQLLKRTV
MLTEKLAGND NLLPGLKFLF AFIETVLSDC GSGIISSRRT TKKCSSGNTS GALGHVDVRP
VGSMKNSETF TLSANQEGSV SLECDATSVD EDEDEDDATS DGEVVSIDKD DEDANSERSL
ASKVCTFTSS GSNFMEQHWY FCYTCDLTIS KGCCSVCAKV CHRGHRVVYS RSSRFFCDCG
AGGVRGSNCQ CLKPRKFIGG SSAPVRGTNT FQQFLPFSED GDQLPDSDSD FDEDMSSDVD
NLVRLSIPKE FQDGILLLLE ELDIENRVLH LCSSLMPSII TRRASHHNKD KKISLGEDKV
ISHGVDLLQL KKAYKSGSID LKIKVDYSNA KELKSQLASG TLVKSLLSVS IRGRLAVGEG
DKVSIFDVGQ LIGQATIVPV TVDKTNVKPL SKNVVRFEIV QLAFNPVVEN YLVVAGYEDC
QVLTLNPRGE VIDRLAIDLA LHGAYVRRVD WLPGSQVQLM VVTNRFVKIY DLSLDNISPL
HYFTLPDDLI VDATLYPASQ GKMFLVILSE NGNIFRLELS VNGNVGAIPL KEVIQVQGKE
IHSKGSSLYF SSTYRLLFIS FHDGTTLIGQ LSSDAASLVE FSSIYEEQES KLLPAGIHHW
RELLSGSGLF ICLSSMKSNS ALAVSMGEHE MFAQSMRHSV GSTSPIVGVT AYKPVSKDKI
HCLVLHDDGS LQIYSHAPVG VDASVSAASE KVKKLGSGIL NKAYAGTNPE FPLDFFEKTM
CITSDVKLGG DAIRNGDTEG AKQSLLNEDG FLESPSPGGF KISVFNSNPD IVMVGFRVHV
GNTSASHIPS SISIFQRVIK LDEGMRSWYD IPFTVAESLL ADEEFSLSVG PAFNGSSLPR
VDSLEIYGRA KDEFGWKEKM DAILDMEARV LGSNSSHNGS GKKHRSIQSA SIQEQVIADG
LQLITKFYSS CRQLGCSRLE EARMELGRLK CKQLLEAIFE SDQEPVLQAS ACHVLQAVFP
KKEIYHQVKD TMWLLGVVKS SSSLLSRLAL GGTVGSWIID EFTAQMRAVC KIALQRRSNF
ATFLETNGSQ VLDSLMQVLW GILDFGKPDT QTMNSIVMSA VELIYCYAEC LALHGKDAGV
CSVAPAVVLL KKLLFSSNEA VQTASSLAIS SRFLQVPFPK QTMLATDDAA EGVVTIPGPA
DTSVGNNQVM VEEDAITSSV QFSCDGCSTV PILRRRWHCS ICPDFDLCEA CYEVLDSDRL
PPPHSRDHPM TAIPIEVDSV GDGNEFHFTP EDVSDPNLLS VPADSNTHSS SPSIHVLEPN
DSGGFSASLT DPVSISASKR AINSLLLSGL LEQLKGWMDT TSGVQAIPVM QLFYRLSSAV
GGPFIDSSKP DSLDLEKLIK WFLDEINLNR PFVARIRSSF GEVAIVVFMF FTLMLRNWHQ
PGGDGSMPRQ SETTCTLDKN VIQFPPSTSA SAKTSVDDQE KNDFASQLIQ ACDSLRQQSF
VNYLMDILQQ LVHVFKSPVN NESMHSLNTG LGCGALLTVR RDLPAGNFLP FFSDSYAKAH
RTDIFIDYHR LLLENAFRLV YTLVRPEKHD RTGEKEKVYK MSYGRDLKLD GYQDVLCSYI
NNPHTNFVRR YARRLFLHLC GSKSHYYSVR DTWQFSSEVK RLYKHINKSG GFQNPIPYER
SVKIVKCLSL MAEVAAARPR NWQKYCLRHG DILSFLMNGV FYFGEESVIQ TLKLLNLAFY
TGKDNSHTSQ KTESTDVRSN KSGTTLQESK KKKKGEDGPE SGSEKSYLDM EALVDVFSDK
NGDALQQFID CFLLEWNSST VRGEAKLVLC GVWHHAKPTF KDTMLMALLQ KVKFLPMYGQ
NIVEYTELVT WLLGKSPDTG SKHHISELVD RCLTPDVIKC IFETLHSQNE LLANHPNSCI
YNTLSGIVEF DGYYLESEPC VACSSPEVPY SRMKLESLKS ETKFTDNRII VKCTGSYTIQ
TVTMNVHDAR KSKSVKVLNL YYNNRPVSDL SELKNNWSLW KRAKSCHLAF NQTELKVEFP
IPITACNFMI ELDSFYENLQ ALSLEPLQCP RCSRPVTDKH GICSNCRENA YQCRQCRNIN
YENLDSFLCN ECGYSKYGRF EFNFMAKPSF TFDNMENDED MKRGLTAIES ESENAHRRYQ
QLLSFKKPLL KIVSSIGENE MDSQQKDSVQ QMMVSLPGPS CKINRKIALL GVLYGEKCKA
AFDSVSKSVQ TLQGLRKVLM NYLHLKHSGN GVASRFVVSR SPNNCYGCAT TFITQCLELL
HVLARHPNSK KQLVSAGILS ELFENNIHQG PKASRFQARA VLCSLSEGDV NAVTKLNSLL
QKKVMYCLEH HRSMDIAVTT REEMLLLSEV CSLADEFWES RLRIVFQLLF SSIKLGAKHP
AISEYVILPC LRIVSQACTP PKPDTPEKED GLGKPSVQTK DESDPNVSGS ITSAVVGTKS
FCDPSERNWD ATPKTRDIQL LSYSEWERGA SYLDFVRRQY KVSQAVKGAG QRLRSQRHDY
LALKYALRWK RRACKTAKSD LSSVFELGSW VKELILSACS QSIKSEMCML ISLLCAQSSS
RKFRLLNLLV SLLPATLSVG ESAAEYFELL FKMTDSEDAR LFLTVRGCLQ TICTLITQEV
SKVESLERSL HIDISQGFIL HKLIELLSKF LEVPNVRSRF MRDYLLSEVL EALIVIRGLI
VQKTKLISDC SRLLKDLLDS LLLENSENNR QFIKACINGL QIHGEERKGR ACLFILEQLC
NLICPSKSEP AYFLVLNKAH TQEEFIRGSM TKNPYSSAEI GPLMRDVKNK ICHQLDLLGL
VEDDYGMELL VAGNIISLDL SIAQVYELVW KKSNQSSNNV TNPNLLSPNT VASSRDFPPM
TVTYRLQGVD GEATEPMIKE LEEDREESQD PEVEFAIAGA VRECGGLQIL LGMIQHLRDD
FKSNQEQLVA VLNLLMYCCK IRENRRALLK LGALGLLLET ARRAFSVDAM EPAEGILLIV
ETLTLEANES DNISITQSAL TVSSEEAGTG EQAKKIVLMF LERLSHPLSL KKSNKQQRNT
EMVARILPYL TYGEPAAMDA LVQHFSPYLQ DWGAFDLLQK QHLDNPKDEN MAQQAAKQRF
TLENFVRVSE SLKTSSCGER LKDIIVEKGI TGTAIRHLKH SFANAEQAGF KTSAEWGLGL
KLPSVPLILS MLRGLSMGHL LTQRCIDEEG ILPLLHALER VSGENEIGAR AENLLDMLSN
KEGKGDGFLE EKVRKLRHAT RDEMRRRALQ KRQELLQGLG MRQELSSDGG ERIVVSQLVL
EGLEDVQEEE DGLACMVCRE GYSLRPADLL GVYSYSKRVN LGVGASGSAR GECVYTTVSY
FNIIHFQCHQ EAKRADAALK SPKKEWEGAT LRNNESLCNS LFPVKGPSVP LTQYIRYVEQ
YWDNLSALGR ADGSRLRLLT YDIVLVCCSA AMYIFSLFYF LV
//
