ID A0A1J7HS30_LUPAN Unreviewed; 441 AA.
AC A0A1J7HS30;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE RecName: Full=Inositol-pentakisphosphate 2-kinase {ECO:0000256|ARBA:ARBA00012023, ECO:0000256|RuleBase:RU364126};
DE EC=2.7.1.158 {ECO:0000256|ARBA:ARBA00012023, ECO:0000256|RuleBase:RU364126};
GN ORFNames=TanjilG_08191 {ECO:0000313|EMBL:OIW15615.1};
OS Lupinus angustifolius (Narrow-leaved blue lupine).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC genistoids sensu lato; core genistoids; Genisteae; Lupinus.
OX NCBI_TaxID=3871 {ECO:0000313|EMBL:OIW15615.1, ECO:0000313|Proteomes:UP000188354};
RN [1] {ECO:0000313|EMBL:OIW15615.1, ECO:0000313|Proteomes:UP000188354}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Tanjil {ECO:0000313|Proteomes:UP000188354};
RC TISSUE=Whole plant {ECO:0000313|EMBL:OIW15615.1};
RX PubMed=27557478; DOI=10.1111/pbi.12615;
RA Hane J.K., Ming Y., Kamphuis L.G., Nelson M.N., Garg G., Atkins C.A.,
RA Bayer P.E., Bravo A., Bringans S., Cannon S., Edwards D., Foley R.,
RA Gao L.L., Harrison M.J., Huang W., Hurgobin B., Li S., Liu C.W.,
RA McGrath A., Morahan G., Murray J., Weller J., Jian J., Singh K.B.;
RT "A comprehensive draft genome sequence for lupin (Lupinus angustifolius),
RT an emerging health food: insights into plant-microbe interactions and
RT legume evolution.";
RL Plant Biotechnol. J. 15:318-330(2017).
CC -!- FUNCTION: Phosphorylates Ins(1,3,4,5,6)P5 at position 2 to form
CC Ins(1,2,3,4,5,6)P6 (InsP6 or phytate). {ECO:0000256|RuleBase:RU364126}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=1D-myo-inositol 1,3,4,5,6-pentakisphosphate + ATP = 1D-myo-
CC inositol hexakisphosphate + ADP + H(+); Xref=Rhea:RHEA:20313,
CC ChEBI:CHEBI:15378, ChEBI:CHEBI:30616, ChEBI:CHEBI:57733,
CC ChEBI:CHEBI:58130, ChEBI:CHEBI:456216; EC=2.7.1.158;
CC Evidence={ECO:0000256|RuleBase:RU364126};
CC -!- DOMAIN: The EXKPK motif is conserved in inositol-pentakisphosphate 2-
CC kinases of both family 1 and 2. {ECO:0000256|RuleBase:RU364126}.
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DR EMBL; CM007363; OIW15615.1; -; Genomic_DNA.
DR RefSeq; XP_019436899.1; XM_019581354.1.
DR RefSeq; XP_019436900.1; XM_019581355.1.
DR RefSeq; XP_019436901.1; XM_019581356.1.
DR AlphaFoldDB; A0A1J7HS30; -.
DR STRING; 3871.A0A1J7HS30; -.
DR EnsemblPlants; OIW15615; OIW15615; TanjilG_08191.
DR GeneID; 109343173; -.
DR Gramene; OIW15615; OIW15615; TanjilG_08191.
DR KEGG; lang:109343173; -.
DR OMA; WKYISEG; -.
DR OrthoDB; 8233at2759; -.
DR Proteomes; UP000188354; Chromosome LG03.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0035299; F:inositol pentakisphosphate 2-kinase activity; IEA:UniProtKB-EC.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR Gene3D; 3.30.200.110; Inositol-pentakisphosphate 2-kinase, N-lobe; 1.
DR InterPro; IPR009286; Ins_P5_2-kin.
DR InterPro; IPR043001; IP5_2-K_N_lobe.
DR PANTHER; PTHR14456; INOSITOL POLYPHOSPHATE KINASE 1; 1.
DR PANTHER; PTHR14456:SF6; INOSITOL-PENTAKISPHOSPHATE 2-KINASE; 1.
DR Pfam; PF06090; Ins_P5_2-kin; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|RuleBase:RU364126};
KW Kinase {ECO:0000256|RuleBase:RU364126};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU364126};
KW Reference proteome {ECO:0000313|Proteomes:UP000188354};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU364126}.
SQ SEQUENCE 441 AA; 49309 MW; 4E99E3AA5E78826A CRC64;
MELALTEEDS AQWVYRGEGA VNLVLSYTGS SPSFIGKVMR IRKVPRNGSK GVKISNLALS
EHECLVWKDV VELISSSDEE IANQQYLQHV LQPLLGSKFI DAGVHVSVSR EFLESVEKNV
ISQRPAWRVD AAGVDTHCDF GLLMSDHSLF ANGSQGSGPC ISVEIKPKCG FLPLSRFISD
GTAIKKKITR YEMHQALKLH QGEISHLSAY NPLDLFSGSK ERIHKAVKDL FTTPQNNFRV
FLNGSLILGG LGGAAENTNL CVAKAFEDEL KSVIQADSGL CTENFFTLIA ETLKKSGVLD
QLLEVQKLDT IDIEGVIHAY YDITSQKCLV CRDLSEEEVK RYASLHSASL DESLRIVKDY
LIAATAKDCS LMICFRPKKE EDSGSVYNNV YLESTKQAFD FKVYFIDLDL KHLNKVEGYY
KLDKKIVSCY KQMIKMDEEM E
//
