ID A0A1J7HXP0_LUPAN Unreviewed; 669 AA.
AC A0A1J7HXP0;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=NAD(P)-binding domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=TanjilG_03696 {ECO:0000313|EMBL:OIW05307.1};
OS Lupinus angustifolius (Narrow-leaved blue lupine).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC genistoids sensu lato; core genistoids; Genisteae; Lupinus.
OX NCBI_TaxID=3871 {ECO:0000313|EMBL:OIW05307.1, ECO:0000313|Proteomes:UP000188354};
RN [1] {ECO:0000313|EMBL:OIW05307.1, ECO:0000313|Proteomes:UP000188354}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Tanjil {ECO:0000313|Proteomes:UP000188354};
RC TISSUE=Whole plant {ECO:0000313|EMBL:OIW05307.1};
RX PubMed=27557478; DOI=10.1111/pbi.12615;
RA Hane J.K., Ming Y., Kamphuis L.G., Nelson M.N., Garg G., Atkins C.A.,
RA Bayer P.E., Bravo A., Bringans S., Cannon S., Edwards D., Foley R.,
RA Gao L.L., Harrison M.J., Huang W., Hurgobin B., Li S., Liu C.W.,
RA McGrath A., Morahan G., Murray J., Weller J., Jian J., Singh K.B.;
RT "A comprehensive draft genome sequence for lupin (Lupinus angustifolius),
RT an emerging health food: insights into plant-microbe interactions and
RT legume evolution.";
RL Plant Biotechnol. J. 15:318-330(2017).
CC -!- COFACTOR:
CC Name=NAD(+); Xref=ChEBI:CHEBI:57540;
CC Evidence={ECO:0000256|ARBA:ARBA00001911};
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DR EMBL; CM007369; OIW05307.1; -; Genomic_DNA.
DR RefSeq; XP_019455512.1; XM_019599967.1.
DR RefSeq; XP_019455513.1; XM_019599968.1.
DR RefSeq; XP_019455514.1; XM_019599969.1.
DR RefSeq; XP_019455515.1; XM_019599970.1.
DR AlphaFoldDB; A0A1J7HXP0; -.
DR STRING; 3871.A0A1J7HXP0; -.
DR EnsemblPlants; OIW05307; OIW05307; TanjilG_03696.
DR GeneID; 109356574; -.
DR Gramene; OIW05307; OIW05307; TanjilG_03696.
DR KEGG; lang:109356574; -.
DR OMA; PRMLMMA; -.
DR OrthoDB; 5486426at2759; -.
DR Proteomes; UP000188354; Chromosome LG09.
DR GO; GO:0008460; F:dTDP-glucose 4,6-dehydratase activity; IEA:InterPro.
DR GO; GO:0009225; P:nucleotide-sugar metabolic process; IEA:InterPro.
DR CDD; cd05246; dTDP_GD_SDR_e; 1.
DR CDD; cd05254; dTDP_HR_like_SDR_e; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR Gene3D; 3.90.25.10; UDP-galactose 4-epimerase, domain 1; 1.
DR InterPro; IPR005888; dTDP_Gluc_deHydtase.
DR InterPro; IPR016040; NAD(P)-bd_dom.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR029903; RmlD-like-bd.
DR NCBIfam; TIGR01181; dTDP_gluc_dehyt; 1.
DR PANTHER; PTHR43000:SF7; DTDP-D-GLUCOSE 4,6-DEHYDRATASE; 1.
DR PANTHER; PTHR43000; DTDP-D-GLUCOSE 4,6-DEHYDRATASE-RELATED; 1.
DR Pfam; PF16363; GDP_Man_Dehyd; 1.
DR Pfam; PF04321; RmlD_sub_bind; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 2.
PE 4: Predicted;
KW NAD {ECO:0000256|ARBA:ARBA00023027};
KW Reference proteome {ECO:0000313|Proteomes:UP000188354}.
FT DOMAIN 10..315
FT /note="NAD(P)-binding"
FT /evidence="ECO:0000259|Pfam:PF16363"
FT DOMAIN 385..555
FT /note="RmlD-like substrate binding"
FT /evidence="ECO:0000259|Pfam:PF04321"
FT REGION 344..364
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 669 AA; 75407 MW; BD0407B3A5CA0311 CRC64;
MATHTPKNIL ITGAAGFIAS HFANRLVRNY PEYKIVVLDK LDYCSNLKNL IPSKSSPNFK
FVKGDIGSAD LVNYLLITES IDTIMHFAAQ THVDNSFGNS FEFTKNNIYG THVLLEACKV
TGQIKRFIHV STDEVYGETD EDAVVGNHEA SQLLPTNPYS ATKAAAEMLV MAYGRSYGLP
VITTRGNNVY GPNQFPEKLI PKFILLAMQG KPLPIHGDGS NVRSYLYCED VAEAFELILH
KGEVGHVYNI GTKRERSVID VAQDICRLFS MDPETSIKFV ENRPFNDQRY FLDDEKLKIL
GWSERTTWDE GLKKTIDWYT KNPNWWGDVS GALLPHPRML MMPGGLERHS DGSEDEKPES
YVSSNTRMVV PPTKNVVTSQ KHPLKFLIYG RTGWIGGLLG KLCESQGILY EYGKGRLEDR
SSLVADIQSV KPTHIFNAAG VTGRPNVDWC EIHKTETIRA NVAGTLTLAD VSREHGLLMI
NYATGCIFEY DAAHPDGSGI GFKEEDTPNF MGSFYSKTKA MVEELLKEYD NVCTLRVRMP
ISSDLSNPRN FITKISRYNK VVNIPNSMTI LDELLPISVE MAKRNLRGIW NFTNPGAVSH
NEILEMYRDY INPNFKWNNF TLEEQAKVIV AARSNNEMDA SKLKNEFPEL LSIKESLIKY
VFEPNKKTN
//
