ID   A0A1J7I5P1_9PEZI        Unreviewed;       394 AA.
AC   A0A1J7I5P1;
DT   15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT   15-FEB-2017, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   SubName: Full=Di-copper centre-containing protein {ECO:0000313|EMBL:OIW22959.1};
GN   ORFNames=CONLIGDRAFT_145397 {ECO:0000313|EMBL:OIW22959.1};
OS   Coniochaeta ligniaria NRRL 30616.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Sordariomycetidae; Coniochaetales; Coniochaetaceae; Coniochaeta.
OX   NCBI_TaxID=1408157 {ECO:0000313|EMBL:OIW22959.1, ECO:0000313|Proteomes:UP000182658};
RN   [1] {ECO:0000313|EMBL:OIW22959.1, ECO:0000313|Proteomes:UP000182658}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NRRL 30616 {ECO:0000313|EMBL:OIW22959.1,
RC   ECO:0000313|Proteomes:UP000182658};
RG   DOE Joint Genome Institute;
RA   Jimenez D.J., Hector R.E., Riley R., Sun H., Grigoriev I.V.,
RA   Van Elsas J.D., Nichols N.N.;
RT   "Draft genome sequence of Coniochaeta ligniaria NRRL30616, a
RT   lignocellulolytic fungus for bioabatement of inhibitors in plant biomass
RT   hydrolysates.";
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; KV875109; OIW22959.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1J7I5P1; -.
DR   STRING; 1408157.A0A1J7I5P1; -.
DR   InParanoid; A0A1J7I5P1; -.
DR   OrthoDB; 4070889at2759; -.
DR   Proteomes; UP000182658; Unassembled WGS sequence.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.1280.10; Di-copper center containing domain from catechol oxidase; 1.
DR   InterPro; IPR008922; Di-copper_centre_dom_sf.
DR   InterPro; IPR002227; Tyrosinase_Cu-bd.
DR   PANTHER; PTHR11474:SF125; TYROSINASE COPPER-BINDING DOMAIN-CONTAINING PROTEIN-RELATED; 1.
DR   PANTHER; PTHR11474; TYROSINASE FAMILY MEMBER; 1.
DR   Pfam; PF00264; Tyrosinase; 1.
DR   PRINTS; PR00092; TYROSINASE.
DR   SUPFAM; SSF48056; Di-copper centre-containing domain; 1.
DR   PROSITE; PS00497; TYROSINASE_1; 1.
DR   PROSITE; PS00498; TYROSINASE_2; 1.
PE   4: Predicted;
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Monooxygenase {ECO:0000256|ARBA:ARBA00023033};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023033};
KW   Reference proteome {ECO:0000313|Proteomes:UP000182658};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..24
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           25..394
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5012588727"
FT   DOMAIN          123..140
FT                   /note="Tyrosinase copper-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS00497"
FT   DOMAIN          315..326
FT                   /note="Tyrosinase copper-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS00498"
SQ   SEQUENCE   394 AA;  42459 MW;  C000646B044B8FD4 CRC64;
     MMFSPLRTST ALLLLSAISA PVTGYTPAST AETDVLAALA AGKLALYYTQ QRRAGNHTSC
     TLENVAVRRE WSTLSSSDRI AYTNAVNCLM SKPSLNNASE VPGAKSRFDD FVAVHINQTL
     FIHGTANFLS WHRFFTWTYE QALRNECGYT GYQPYWNWGK SAFDPIHSPY FDGTPTSVGG
     NGVFEPHNCT SGLPTGLNCI PPGEGGGCVT AGPFANMSVN MGPISPTLAE PDAVPASSLY
     AYNPRCLKRD VSSWVSSRWT TDRNSSDLIA RSGDIVAFQT TMQGDFASGV YGVHTGGHFV
     LGGDPGGDLF ASPGDPAFYL HHAQIDRTWW VWQNLDPEER TRAIGGSISL LDPTARNGTL
     EDVIDLGVNA EAITIEKVMS TVGLTGGPLC YVYV
//