ID A0A1J7IT00_LUPAN Unreviewed; 443 AA.
AC A0A1J7IT00;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=Enhancer of polycomb-like protein {ECO:0000256|RuleBase:RU361124};
GN ORFNames=TanjilG_08842 {ECO:0000313|EMBL:OIW17564.1};
OS Lupinus angustifolius (Narrow-leaved blue lupine).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC genistoids sensu lato; core genistoids; Genisteae; Lupinus.
OX NCBI_TaxID=3871 {ECO:0000313|EMBL:OIW17564.1, ECO:0000313|Proteomes:UP000188354};
RN [1] {ECO:0000313|EMBL:OIW17564.1, ECO:0000313|Proteomes:UP000188354}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Tanjil {ECO:0000313|Proteomes:UP000188354};
RC TISSUE=Whole plant {ECO:0000313|EMBL:OIW17564.1};
RX PubMed=27557478; DOI=10.1111/pbi.12615;
RA Hane J.K., Ming Y., Kamphuis L.G., Nelson M.N., Garg G., Atkins C.A.,
RA Bayer P.E., Bravo A., Bringans S., Cannon S., Edwards D., Foley R.,
RA Gao L.L., Harrison M.J., Huang W., Hurgobin B., Li S., Liu C.W.,
RA McGrath A., Morahan G., Murray J., Weller J., Jian J., Singh K.B.;
RT "A comprehensive draft genome sequence for lupin (Lupinus angustifolius),
RT an emerging health food: insights into plant-microbe interactions and
RT legume evolution.";
RL Plant Biotechnol. J. 15:318-330(2017).
CC -!- FUNCTION: Component of the NuA4 histone acetyltransferase complex which
CC is involved in transcriptional activation of selected genes principally
CC by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is
CC also involved in DNA repair. Involved in gene silencing by neighboring
CC heterochromatin, blockage of the silencing spreading along the
CC chromosome, and required for cell cycle progression through G2/M.
CC {ECO:0000256|ARBA:ARBA00025513}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|RuleBase:RU361124}.
CC -!- SIMILARITY: Belongs to the enhancer of polycomb family.
CC {ECO:0000256|ARBA:ARBA00008035, ECO:0000256|RuleBase:RU361124}.
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DR EMBL; CM007362; OIW17564.1; -; Genomic_DNA.
DR RefSeq; XP_019418931.1; XM_019563386.1.
DR RefSeq; XP_019418940.1; XM_019563395.1.
DR AlphaFoldDB; A0A1J7IT00; -.
DR STRING; 3871.A0A1J7IT00; -.
DR EnsemblPlants; OIW17564; OIW17564; TanjilG_08842.
DR GeneID; 109329663; -.
DR Gramene; OIW17564; OIW17564; TanjilG_08842.
DR KEGG; lang:109329663; -.
DR OMA; YWAAKRQ; -.
DR OrthoDB; 1343374at2759; -.
DR Proteomes; UP000188354; Chromosome LG02.
DR GO; GO:0035267; C:NuA4 histone acetyltransferase complex; IEA:InterPro.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:InterPro.
DR InterPro; IPR024943; Enhancer_polycomb.
DR InterPro; IPR019542; Enhancer_polycomb-like_N.
DR PANTHER; PTHR14898; ENHANCER OF POLYCOMB; 1.
DR PANTHER; PTHR14898:SF0; ENHANCER OF POLYCOMB-LIKE PROTEIN; 1.
DR Pfam; PF10513; EPL1; 1.
PE 3: Inferred from homology;
KW Cell cycle {ECO:0000256|ARBA:ARBA00023306};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU361124};
KW Reference proteome {ECO:0000313|Proteomes:UP000188354};
KW Transcription {ECO:0000256|ARBA:ARBA00023163,
KW ECO:0000256|RuleBase:RU361124};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015,
KW ECO:0000256|RuleBase:RU361124}.
FT DOMAIN 52..137
FT /note="Enhancer of polycomb-like N-terminal"
FT /evidence="ECO:0000259|Pfam:PF10513"
FT COILED 245..285
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 443 AA; 51597 MW; D4545E1F73375208 CRC64;
MTRLSFRPRP LDIHKKLPIV KSIKEFEDDD TPTSTRNSLF LRIAPDVDNE VHPVPSRRLA
SEIPTPQFVV VDTYERDYSC TFSQPNTYLR ARGAWAEIGD FVEYDLDNED EDWLLEFNEE
RKIMTPEMFE SLIFKFEVLD LKARERAGLI TPTLGSPIPV LLRLDAAIEV LQAQPVKYAI
IQSVYDYWKE KRERWQKPIL RRLQPPPPAN DANPFNVFRP REKAHRLHTR RMQRRENNLP
SFEKLRQVRR NLDQAKSMLQ ALIKREEKKR EVVDSEVTLQ RMQMKYKHET EFLEDSLALP
GFTEEEYFDS DDMITGHPHT WSSAVPSLPS YDTNLLTVPT VLPKQEFKRQ YVPQGWPRKL
DPLDPVMLFT KPLLPEKLAM AGILPPSDSS TANGVSAQSY EFRGRIGRGG RIIFDRRNPL
LQTAIDCGNS YYIPPKPRPS FNM
//