ID A0A1J7K0S8_9PEZI Unreviewed; 1247 AA.
AC A0A1J7K0S8;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE RecName: Full=PNPLA domain-containing protein {ECO:0000259|PROSITE:PS51635};
GN ORFNames=CONLIGDRAFT_53333 {ECO:0000313|EMBL:OIW35316.1};
OS Coniochaeta ligniaria NRRL 30616.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Sordariomycetidae; Coniochaetales; Coniochaetaceae; Coniochaeta.
OX NCBI_TaxID=1408157 {ECO:0000313|EMBL:OIW35316.1, ECO:0000313|Proteomes:UP000182658};
RN [1] {ECO:0000313|EMBL:OIW35316.1, ECO:0000313|Proteomes:UP000182658}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL 30616 {ECO:0000313|EMBL:OIW35316.1,
RC ECO:0000313|Proteomes:UP000182658};
RG DOE Joint Genome Institute;
RA Jimenez D.J., Hector R.E., Riley R., Sun H., Grigoriev I.V.,
RA Van Elsas J.D., Nichols N.N.;
RT "Draft genome sequence of Coniochaeta ligniaria NRRL30616, a
RT lignocellulolytic fungus for bioabatement of inhibitors in plant biomass
RT hydrolysates.";
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KV875093; OIW35316.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1J7K0S8; -.
DR STRING; 1408157.A0A1J7K0S8; -.
DR InParanoid; A0A1J7K0S8; -.
DR OrthoDB; 2093603at2759; -.
DR Proteomes; UP000182658; Unassembled WGS sequence.
DR GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0046486; P:glycerolipid metabolic process; IEA:UniProt.
DR GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-UniRule.
DR CDD; cd07216; Pat17_PNPLA8_PNPLA9_like3; 1.
DR Gene3D; 3.40.1090.10; Cytosolic phospholipase A2 catalytic domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 2.
DR InterPro; IPR016035; Acyl_Trfase/lysoPLipase.
DR InterPro; IPR002182; NB-ARC.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR002641; PNPLA_dom.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR24185; CALCIUM-INDEPENDENT PHOSPHOLIPASE A2-GAMMA; 1.
DR PANTHER; PTHR24185:SF1; CALCIUM-INDEPENDENT PHOSPHOLIPASE A2-GAMMA; 1.
DR Pfam; PF00931; NB-ARC; 1.
DR Pfam; PF01734; Patatin; 1.
DR Pfam; PF13424; TPR_12; 1.
DR SMART; SM00028; TPR; 3.
DR SUPFAM; SSF52151; FabD/lysophospholipase-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF48452; TPR-like; 2.
DR PROSITE; PS51635; PNPLA; 1.
DR PROSITE; PS50005; TPR; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Lipid degradation {ECO:0000256|ARBA:ARBA00022963};
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00023098};
KW Reference proteome {ECO:0000313|Proteomes:UP000182658};
KW TPR repeat {ECO:0000256|PROSITE-ProRule:PRU00339}.
FT DOMAIN 13..214
FT /note="PNPLA"
FT /evidence="ECO:0000259|PROSITE:PS51635"
FT REPEAT 799..832
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REGION 879..898
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1221..1247
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1247 AA; 140208 MW; 8AB88B8EC5D2800C CRC64;
MSIPDENGPL YLLSLDGGGI RGVSELVMLD CIMRRLQKKK GLDELPKPCD YFDLIAGTST
GGLIAILLGR LRMTTQEALD AYDDVAETLF SRSNRKYLAK SQFKSTTLED VVKEIVAQRS
SSDLLKYQDK DEQKGKAFVC AIDEKELGAI HRLRTYNIDG TSDEGLKDCK VWEAARATTA
APLNFKPMTI QRDSDKTTYI DAALGYNNPV EQLLEEAGNI FHSKRTLGAI VSLGTGTRKL
GLASPEDVNG LGYGLSIVAT LKNETTDTER PHKRLQAKFK KFPNTYFRFN VPDGADEVKL
AEWRKMGELK KLTTDYIGNE AVDQEINDLV EVLSKRKTAG LTLGHICLLD SKQLLMNSHL
AQHMGTSSNF FTGRTKVLES LEDRFFLREP GERGRREFLI CGMGGAGKTQ IALKFVETKA
KLLFKRCFWI DATDGATAQE GYQEFASEAF PDKEVTTVSM AAVQKWMADL DEEWLLVLDN
SNEENMRQFV PPGNTGNIIY TSRRHNLAAS LQPEWVAEVN DMEPEDAITL LLRTAGHIPY
NRELRAEASP VVAELGCLPL AIDQAGAYIR RMGGSLSDYL ALFKSQRQRL LQDPDFKGLL
RDPRFKGTDP RNQAVYATFD ISYNALREIA HEHEGSVKGE DARNALKILR LICFYHNDTL
VLEMFDRASI WGERVAPKLN YPLGKGKDAL DNLIAVRDNV WDSNPVMFGL MVLEDFSLVK
WDHYRLHVSM HVLVHDWALT SIGKKDMARL AGYAKAILFG SISYDTHVES YRFHRRIYPH
VEACLRRANM SQEDTRAQAG YQMKLGTLYE QSGQFESARD AFHKSIGLWK TERGPDDHLT
LRAMSLLASL EKADGKLGEA AFVLLQILEL RQMRIDDLSS RQDKRNPEDL KRQARRGVES
DDDEQLLKRL RLKSAMDWAQ LAVVYMGQSH LDAAEHAMLQ TVEIRKAVAP ETAAWAERHL
TKIRLARAQD ATYNLDDSPR ADSRRSVEDA RASLAEAIEE HGHDHRDTIR ALGALAKAEM
DAGNGEAAEE IAKEFARRCT EVYGEDGRKT LAAIELYSKV LQHNEQHIDA AGMRTLILTY
SQRTLGIYHP DTIEALLKLG VGLGFQGRFE EAVIIATRAV ELLEGIHGAT HRAVLSFRKT
LEIVKSNAAR ATPNTRRQMA RDALRKYHEH GGGDHYVVDD DFVDRWANVV HLSMFWPTGI
GEPEEVYFAE RPPVVNSVVV AEEEEQQARP TQQELPLDRE SLADEFA
//
