ID A0A1J8QJM1_9AGAM Unreviewed; 1160 AA.
AC A0A1J8QJM1;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 24-JAN-2024, entry version 26.
DE RecName: Full=PIN domain-like protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=AZE42_03967 {ECO:0000313|EMBL:OJA13616.1};
OS Rhizopogon vesiculosus.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Agaricomycetidae; Boletales; Suillineae; Rhizopogonaceae; Rhizopogon.
OX NCBI_TaxID=180088 {ECO:0000313|EMBL:OJA13616.1, ECO:0000313|Proteomes:UP000183567};
RN [1] {ECO:0000313|EMBL:OJA13616.1, ECO:0000313|Proteomes:UP000183567}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AM-OR11-056 {ECO:0000313|EMBL:OJA13616.1,
RC ECO:0000313|Proteomes:UP000183567};
RA Mujic A.B., Kuo A., Tritt A., Lipzen A., Chen C., Johnson J., Sharma A.,
RA Barry K., Grigoriev I.V., Spatafora J.W.;
RT "Comparative genomics of the ectomycorrhizal sister species Rhizopogon
RT vinicolor and Rhizopogon vesiculosus (Basidiomycota: Boletales) reveals a
RT divergence of the mating type B locus.";
RL Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the XPG/RAD2 endonuclease family. XPG subfamily.
CC {ECO:0000256|ARBA:ARBA00005283}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OJA13616.1}.
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DR EMBL; LVVM01004089; OJA13616.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1J8QJM1; -.
DR STRING; 180088.A0A1J8QJM1; -.
DR OrthoDB; 5479162at2759; -.
DR Proteomes; UP000183567; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0004519; F:endonuclease activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0003697; F:single-stranded DNA binding; IEA:InterPro.
DR GO; GO:0006289; P:nucleotide-excision repair; IEA:InterPro.
DR CDD; cd09904; H3TH_XPG; 1.
DR CDD; cd09868; PIN_XPG_RAD2; 2.
DR Gene3D; 1.10.150.20; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR Gene3D; 3.40.50.1010; 5'-nuclease; 2.
DR InterPro; IPR036279; 5-3_exonuclease_C_sf.
DR InterPro; IPR008918; HhH2.
DR InterPro; IPR029060; PIN-like_dom_sf.
DR InterPro; IPR006086; XPG-I_dom.
DR InterPro; IPR006084; XPG/Rad2.
DR InterPro; IPR001044; XPG/Rad2_eukaryotes.
DR InterPro; IPR019974; XPG_CS.
DR InterPro; IPR006085; XPG_DNA_repair_N.
DR PANTHER; PTHR16171:SF7; DNA EXCISION REPAIR PROTEIN ERCC-5; 1.
DR PANTHER; PTHR16171; DNA REPAIR PROTEIN COMPLEMENTING XP-G CELLS-RELATED; 1.
DR Pfam; PF00867; XPG_I; 1.
DR Pfam; PF00752; XPG_N; 1.
DR PRINTS; PR00853; XPGRADSUPER.
DR PRINTS; PR00066; XRODRMPGMNTG.
DR SMART; SM00279; HhH2; 1.
DR SMART; SM00484; XPGI; 1.
DR SMART; SM00485; XPGN; 1.
DR SUPFAM; SSF47807; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR SUPFAM; SSF88723; PIN domain-like; 1.
DR PROSITE; PS00841; XPG_1; 1.
DR PROSITE; PS00842; XPG_2; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nuclease {ECO:0000256|ARBA:ARBA00022722};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000183567}.
FT DOMAIN 1..98
FT /note="XPG N-terminal"
FT /evidence="ECO:0000259|SMART:SM00485"
FT DOMAIN 770..839
FT /note="XPG-I"
FT /evidence="ECO:0000259|SMART:SM00484"
FT REGION 154..184
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 447..489
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 531..550
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 563..617
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 630..689
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1025..1160
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 729..760
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 168..184
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 447..461
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 531..545
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 636..659
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1025..1039
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1093..1107
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1141..1160
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1160 AA; 128409 MW; 3775D996421930AF CRC64;
MGVKSLWSLL SPVGRPVPLE TIEGKVLAID SSIWIYQFQA TMRDKDGRAL VNAHVLGFLR
RICKLLFYGI RPVFVFDGGA PALKRNTISE RKKKKSGAAA TYAKVAERLL AAQLRREALV
HAPASHPPSS KGKQKAPSGP VVLDENAVYL EDIDGSAPKT PAKKKAEQTP PSSKKKNRFH
DHDPYRLPEV DLEARIANVT RSQAPDPRLA TEEELRAFIE EMRPEDFDVT SEAFRELPTE
VQYEIVGDLR LKSRQTSYTR LQNMLRKAVT PLDFSREQIK NLKQRNALTQ QLLTTTDSIG
KAHITIPVRI ASERNREYVL VKNEGADGGW VLGIRDEGTR SKPIEIDQEE PTLQSDSEED
MEMEEVSIPG IGTPDPDLRE FQSSMALHAI GQRSQPFVPK PVQRRIKSTP LFELDDDDDI
PRPPIRDEFD DIEVALAIQA SLEDHAADYN PSTSEPSSSK LGPPATPQPK PALQTHDSDD
DLYTSPSRLE TALSIAGAGP PRRISGALHD LSPQISFGKA PLLVSPKIVS HPLPSVQSSS
PESDESMDEV LPVPVSQSLE APDRLAAPAV VSTHPEPPQS PQVVHNAELD SDEDMEEVVV
IDEGHDQESL DSSTPVTLSA PEAVVVAKER RASPHPSFQL SETLEDHSLL SSSGVVTSRA
PIPENDDESA IEWSRSPSPV HGAVPESTEQ GVSATSAAAE TWDAAQEMDP HVEQGEFARF
MSQVKGKDLE VVRHEIDEEI RTLNQQKKAA MRDSEDITQQ MISQIMLMLR LFGIPYITAP
MEAEAQCAEL VSLGLVEGII TDDSDVFLFG GMRVFKNMFN QSKTVECFLL SDLSRELGLE
RDTLIHLAYL LGSDYVEGLS GVGPVVAMEL LKEFPGEDGL HKFKDWWSKV QSGRDREEDN
KTRFRNRFKK KFKDLYLPLE WPNPLVRDAY YHPTVDSSEE PFKWGMPDLD ALRHFLHEEL
GWIQSKVDDL LLPIIQIMNK RNQAASMNRQ GNLTSFFDVA PGSGSYAPKK RQAYGSKRLQ
QVVTDFRKQQ AQRKRGSTST AAPDEADDLI PEDDHEPAIK KRKTGAKQKS QTKTIIGAAQ
QKRPRSVARG KSRGSHTRAS TSRAGAEPGS ESGDDYVGND DGPSATKASK PHLRPRARPV
TKGNRKPDRY DGLAADSEGS
//
