ID A0A1J9PT38_9EURO Unreviewed; 607 AA.
AC A0A1J9PT38;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 08-NOV-2023, entry version 22.
DE RecName: Full=Dioxygenase {ECO:0008006|Google:ProtNLM};
GN ORFNames=AJ78_00433 {ECO:0000313|EMBL:OJD19576.1};
OS Emergomyces pasteurianus Ep9510.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Ajellomycetaceae; Emergomyces.
OX NCBI_TaxID=1447872 {ECO:0000313|EMBL:OJD19576.1, ECO:0000313|Proteomes:UP000182235};
RN [1] {ECO:0000313|EMBL:OJD19576.1, ECO:0000313|Proteomes:UP000182235}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UAMH 9510 {ECO:0000313|EMBL:OJD19576.1,
RC ECO:0000313|Proteomes:UP000182235};
RG The Broad Institute Genomics Platform;
RA Cuomo C.A., Munoz J.F., Imamovic A., Priest M.E., Young S., Clay O.K.,
RA McEwen J.G.;
RT "Emmonsia species relationships and genome sequence.";
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Fe(2+); Xref=ChEBI:CHEBI:29033;
CC Evidence={ECO:0000256|PIRSR:PIRSR604294-1};
CC Note=Binds 1 Fe(2+) ion per subunit. {ECO:0000256|PIRSR:PIRSR604294-1};
CC -!- SIMILARITY: Belongs to the carotenoid oxygenase family.
CC {ECO:0000256|ARBA:ARBA00006787}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OJD19576.1}.
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DR EMBL; LGRN01000007; OJD19576.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1J9PT38; -.
DR STRING; 1447872.A0A1J9PT38; -.
DR VEuPathDB; FungiDB:AJ78_00433; -.
DR OrthoDB; 294919at2759; -.
DR Proteomes; UP000182235; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:InterPro.
DR InterPro; IPR004294; Carotenoid_Oase.
DR PANTHER; PTHR10543; BETA-CAROTENE DIOXYGENASE; 1.
DR PANTHER; PTHR10543:SF24; CAROTENOID ISOMEROOXYGENASE; 1.
DR Pfam; PF03055; RPE65; 1.
PE 3: Inferred from homology;
KW Iron {ECO:0000256|ARBA:ARBA00023004, ECO:0000256|PIRSR:PIRSR604294-1};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW ECO:0000256|PIRSR:PIRSR604294-1};
KW Reference proteome {ECO:0000313|Proteomes:UP000182235}.
FT REGION 507..529
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 220
FT /ligand="Fe cation"
FT /ligand_id="ChEBI:CHEBI:24875"
FT /ligand_note="catalytic"
FT /evidence="ECO:0000256|PIRSR:PIRSR604294-1"
FT BINDING 270
FT /ligand="Fe cation"
FT /ligand_id="ChEBI:CHEBI:24875"
FT /ligand_note="catalytic"
FT /evidence="ECO:0000256|PIRSR:PIRSR604294-1"
FT BINDING 344
FT /ligand="Fe cation"
FT /ligand_id="ChEBI:CHEBI:24875"
FT /ligand_note="catalytic"
FT /evidence="ECO:0000256|PIRSR:PIRSR604294-1"
FT BINDING 592
FT /ligand="Fe cation"
FT /ligand_id="ChEBI:CHEBI:24875"
FT /ligand_note="catalytic"
FT /evidence="ECO:0000256|PIRSR:PIRSR604294-1"
SQ SEQUENCE 607 AA; 66970 MW; 9B31520B52044583 CRC64;
MEAVDTSIKS FNDWPNHQGF NSTYEERTPV ELKVTGDIPV WAAGVLYRTG TGRSEIETDQ
KKIFKVAHWF DGMSVVHRFQ ILPPDSAHPS VRVFYNSRSC CDGLIENIRK TGKGKEMSFG
ARYEPCTSYF QKVMSLFRPA PPRTSADQHS MSITLSVNFP GVSNKAIKKI SGHASGIQTL
TNKTDAAVFQ TLDPETLEPV GVASQQILHP DLKGPISAAH AKSDPVTGDV YNFNLQLGKC
PIYRIFHVSA VTGKTSILAT ITNARAAYLH SFFLTENYVI LCVWNSFYTA GGLAILWHKN
IIDAIADYDP SKPATWYVID RRPADRDGKG LVATYRSDPF FCFHTINAYE EPSPDGSGTT
DIVADLTTYS SLDVLKRFYL SNIVSTSPDA SKYATGIGDA GRGVYKRFRL PSLPPLSSSS
KSIRSKPNRV TLDFKANHFN SPELPILNPQ YVTHRHRYVY GVIDTGKSTF IDGLVKFDTE
TKQALYWNEW GQNAGEPIFV ARRNMPKQAD EGGSSRTGSE SGSEKAADTR GDMIEEIEKE
KDPEVLDEDD GVLLSVVLDG LQGKSYLLVL DAKNMKEVGR AEVAGPIGFG FHGTHLSTVS
NGRGLDF
//
