ID A0A1J9QF17_9EURO Unreviewed; 526 AA.
AC A0A1J9QF17;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=Pseudouridine synthase RsuA/RluA-like domain-containing protein {ECO:0000259|Pfam:PF00849};
GN ORFNames=ACJ73_01533 {ECO:0000313|EMBL:OJD27072.1};
OS Blastomyces percursus.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Ajellomycetaceae; Blastomyces.
OX NCBI_TaxID=1658174 {ECO:0000313|EMBL:OJD27072.1, ECO:0000313|Proteomes:UP000242791};
RN [1] {ECO:0000313|EMBL:OJD27072.1, ECO:0000313|Proteomes:UP000242791}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=EI222 {ECO:0000313|EMBL:OJD27072.1,
RC ECO:0000313|Proteomes:UP000242791};
RA Cuomo C.A., Schwartz I.S., Kenyon C., De Hoog G.S., Govender N.P.,
RA Botha A., Moreno L., De Vries M., Munoz J.F., Stielow J.B.;
RT "Emmonsia species relationships and genome sequence.";
RL Submitted (AUG-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the pseudouridine synthase RluA family.
CC {ECO:0000256|ARBA:ARBA00010876}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OJD27072.1}.
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DR EMBL; LGTZ01000141; OJD27072.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1J9QF17; -.
DR STRING; 1658174.A0A1J9QF17; -.
DR VEuPathDB; FungiDB:ACJ73_01533; -.
DR OrthoDB; 5479603at2759; -.
DR Proteomes; UP000242791; Unassembled WGS sequence.
DR GO; GO:0009982; F:pseudouridine synthase activity; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0001522; P:pseudouridine synthesis; IEA:InterPro.
DR CDD; cd02557; PseudoU_synth_ScRIB2; 1.
DR CDD; cd00165; S4; 1.
DR Gene3D; 3.30.2350.10; Pseudouridine synthase; 1.
DR Gene3D; 3.10.290.10; RNA-binding S4 domain; 1.
DR InterPro; IPR020103; PsdUridine_synth_cat_dom_sf.
DR InterPro; IPR006224; PsdUridine_synth_RluA-like_CS.
DR InterPro; IPR006225; PsdUridine_synth_RluC/D.
DR InterPro; IPR006145; PsdUridine_synth_RsuA/RluA.
DR InterPro; IPR036986; S4_RNA-bd_sf.
DR NCBIfam; TIGR00005; rluA_subfam; 1.
DR PANTHER; PTHR21600; MITOCHONDRIAL RNA PSEUDOURIDINE SYNTHASE; 1.
DR PANTHER; PTHR21600:SF40; PSEUDOURIDYLATE SYNTHASE RPUSD2; 1.
DR Pfam; PF00849; PseudoU_synth_2; 1.
DR SUPFAM; SSF55174; Alpha-L RNA-binding motif; 1.
DR SUPFAM; SSF55120; Pseudouridine synthase; 1.
DR PROSITE; PS01129; PSI_RLU; 1.
DR PROSITE; PS50889; S4; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000242791};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00182}.
FT DOMAIN 133..330
FT /note="Pseudouridine synthase RsuA/RluA-like"
FT /evidence="ECO:0000259|Pfam:PF00849"
FT REGION 258..289
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 177
FT /evidence="ECO:0000256|PIRSR:PIRSR606225-1"
SQ SEQUENCE 526 AA; 58481 MW; 8FC41D2C808DB0C1 CRC64;
MALTTVDQPS LVEKKEDFEP PPDVVVTPCD PLPRPYYIEG GLRRVAPYHY TYNTFCKERW
RGRGLLDVFG AEFRDRPREY YQKAIEDGAV CINGKAVSID TKIRNGDVIS HTLHRHEPPV
TSQPIGIIHE DNDMIVIDKP AGVPVHPAGR YNYNSILEIM KSERGNCWVP YPCNRLDRLT
SGVMFIGKHP KGAEQIGEKL RSRTVRKEYV ARVKGKFPDG VVLCDQPMLK ISPILGLNRA
RASGKEARTK FRRIAYYPPH KPVEKSSGSP TGPATPPATL PDRMNISDSP TDTPTGAAIP
VPMSIDEEGY SIVHCLPLTG RTHQLRVHLQ YLGHPITNDP IYSNRRVFGH SLGKADATGE
NDEQIIYRLS KMGKTEPADS LSYQTFQTPP PESVSKNDPA VVDDLLAKEH EVMVNDYLKR
KGEKMNGKQC ETCGTDLYTD PGVHELGIFL HAVAYADITG AWKYKSKMPG WALPPEGMEG
PTTVPDWVDD EDEEVVGKGQ HGDSALVEGL GAVNVTELID KNTREQ
//
