ID   A0A1J9QGU7_9EURO        Unreviewed;       685 AA.
AC   A0A1J9QGU7;
DT   15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT   15-FEB-2017, sequence version 1.
DT   27-MAR-2024, entry version 29.
DE   RecName: Full=RNase III domain-containing protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=AJ78_04573 {ECO:0000313|EMBL:OJD15148.1};
OS   Emergomyces pasteurianus Ep9510.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Onygenales; Ajellomycetaceae; Emergomyces.
OX   NCBI_TaxID=1447872 {ECO:0000313|EMBL:OJD15148.1, ECO:0000313|Proteomes:UP000182235};
RN   [1] {ECO:0000313|EMBL:OJD15148.1, ECO:0000313|Proteomes:UP000182235}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=UAMH 9510 {ECO:0000313|EMBL:OJD15148.1,
RC   ECO:0000313|Proteomes:UP000182235};
RG   The Broad Institute Genomics Platform;
RA   Cuomo C.A., Munoz J.F., Imamovic A., Priest M.E., Young S., Clay O.K.,
RA   McEwen J.G.;
RT   "Emmonsia species relationships and genome sequence.";
RL   Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the AB hydrolase superfamily.
CC       {ECO:0000256|ARBA:ARBA00008645}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OJD15148.1}.
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DR   EMBL; LGRN01000173; OJD15148.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1J9QGU7; -.
DR   STRING; 1447872.A0A1J9QGU7; -.
DR   ESTHER; 9euro-a0a1j9qgu7; ABHD11-Acetyl_transferase.
DR   VEuPathDB; FungiDB:AJ78_04573; -.
DR   OrthoDB; 5475137at2759; -.
DR   Proteomes; UP000182235; Unassembled WGS sequence.
DR   GO; GO:0004525; F:ribonuclease III activity; IEA:InterPro.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006396; P:RNA processing; IEA:InterPro.
DR   CDD; cd00593; RIBOc; 1.
DR   Gene3D; 3.30.160.20; -; 1.
DR   Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR   Gene3D; 1.10.1520.10; Ribonuclease III domain; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR000073; AB_hydrolase_1.
DR   InterPro; IPR014720; dsRBD_dom.
DR   InterPro; IPR000999; RNase_III_dom.
DR   InterPro; IPR036389; RNase_III_sf.
DR   PANTHER; PTHR46118; PROTEIN ABHD11; 1.
DR   PANTHER; PTHR46118:SF4; PROTEIN ABHD11; 1.
DR   Pfam; PF00561; Abhydrolase_1; 1.
DR   Pfam; PF00636; Ribonuclease_3; 1.
DR   SMART; SM00535; RIBOc; 1.
DR   SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR   SUPFAM; SSF54768; dsRNA-binding domain-like; 1.
DR   SUPFAM; SSF69065; RNase III domain-like; 1.
DR   PROSITE; PS50137; DS_RBD; 1.
DR   PROSITE; PS50142; RNASE_3_2; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Reference proteome {ECO:0000313|Proteomes:UP000182235};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|PROSITE-
KW   ProRule:PRU00266}.
FT   DOMAIN          136..252
FT                   /note="RNase III"
FT                   /evidence="ECO:0000259|PROSITE:PS50142"
FT   DOMAIN          282..357
FT                   /note="DRBM"
FT                   /evidence="ECO:0000259|PROSITE:PS50137"
FT   REGION          1..49
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        31..48
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   685 AA;  76660 MW;  33ACBBC17D12DCF6 CRC64;
     MDTKRKLEHD SSRAMTTGNS VKRHKGLRSP EPDTFSSSSG TSSERALKRT AKIQSRLEKL
     RKLTRKLLSH PEQVQAVHGS GQDVIVALAE LGKAFSPTKS TPESLYYSQS PRNRLHLRSL
     QLHAQKALPP LPPVLDKQLQ TAMFTHEGIN NPTTVSLPER NYERMELLGD AYIEIIATRL
     VWDTFPRLPA GRLSQIRELL VKNETLAEYA TLYGLDQKLL VPPDIRNQTK TWTKVKGDVF
     EAYVAAIILS NRENGVQLVE DWLTQLWIPK LEQIEKEKPV LRYKEELAKL IMDKGIKLSY
     VDEKKSASHP GGLQTFFIGV YLTGWGHKNK CLGSGTGLSK VIAGNEAARK ALENPMTHRA
     AAAKQAFQAA KLEGEAAAAA PVHLGPALYH YLKPIETMRS RIARVCRSSY RSFSTSPGRS
     RAQLAYQTWP AQNDSTTIDE RRNPIVFMHG LFGSKQNNRS ISKALGNHLK TRIYALDLRN
     HGDSPHLPEH DYTTMADDVE EFIHNLKLAK PILIGHSMGA KTAMTVALRS PELISSLISV
     DNAPVSAKLG SQFSKYVKGM QEIEGANITK QSEADRILQQ YEESLPIRQF LLTNLMRSKV
     DNTLKFRVPV QLLGESLDEL AGFPFNASDN VKFEGPSLFI RGTKSRYVQK KSFPVIAHFF
     PNYKLVDVDA GHWVISENPE GFKNG
//