ID A0A1J9QJS8_9EURO Unreviewed; 1698 AA.
AC A0A1J9QJS8;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:OJD15469.1};
GN ORFNames=AJ78_04264 {ECO:0000313|EMBL:OJD15469.1};
OS Emergomyces pasteurianus Ep9510.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Ajellomycetaceae; Emergomyces.
OX NCBI_TaxID=1447872 {ECO:0000313|EMBL:OJD15469.1, ECO:0000313|Proteomes:UP000182235};
RN [1] {ECO:0000313|EMBL:OJD15469.1, ECO:0000313|Proteomes:UP000182235}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UAMH 9510 {ECO:0000313|EMBL:OJD15469.1,
RC ECO:0000313|Proteomes:UP000182235};
RG The Broad Institute Genomics Platform;
RA Cuomo C.A., Munoz J.F., Imamovic A., Priest M.E., Young S., Clay O.K.,
RA McEwen J.G.;
RT "Emmonsia species relationships and genome sequence.";
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OJD15469.1}.
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DR EMBL; LGRN01000154; OJD15469.1; -; Genomic_DNA.
DR STRING; 1447872.A0A1J9QJS8; -.
DR VEuPathDB; FungiDB:AJ78_04264; -.
DR OrthoDB; 5476208at2759; -.
DR Proteomes; UP000182235; Unassembled WGS sequence.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
DR GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
DR CDD; cd06224; REM; 1.
DR Gene3D; 1.10.840.10; Ras guanine-nucleotide exchange factors catalytic domain; 1.
DR Gene3D; 1.20.870.10; Son of sevenless (SoS) protein Chain: S domain 1; 1.
DR InterPro; IPR008937; Ras-like_GEF.
DR InterPro; IPR000651; Ras-like_Gua-exchang_fac_N.
DR InterPro; IPR023578; Ras_GEF_dom_sf.
DR InterPro; IPR001895; RASGEF_cat_dom.
DR InterPro; IPR036964; RASGEF_cat_dom_sf.
DR PANTHER; PTHR23113; GUANINE NUCLEOTIDE EXCHANGE FACTOR; 1.
DR PANTHER; PTHR23113:SF364; GUANINE NUCLEOTIDE EXCHANGE FACTOR LTE1; 1.
DR Pfam; PF00617; RasGEF; 1.
DR Pfam; PF00618; RasGEF_N; 1.
DR SMART; SM00147; RasGEF; 1.
DR SMART; SM00229; RasGEFN; 1.
DR SUPFAM; SSF48366; Ras GEF; 1.
DR PROSITE; PS50009; RASGEF_CAT; 1.
DR PROSITE; PS50212; RASGEF_NTER; 1.
PE 4: Predicted;
KW Guanine-nucleotide releasing factor {ECO:0000256|ARBA:ARBA00022658,
KW ECO:0000256|PROSITE-ProRule:PRU00168};
KW Reference proteome {ECO:0000313|Proteomes:UP000182235}.
FT DOMAIN 374..499
FT /note="N-terminal Ras-GEF"
FT /evidence="ECO:0000259|PROSITE:PS50212"
FT DOMAIN 1450..1693
FT /note="Ras-GEF"
FT /evidence="ECO:0000259|PROSITE:PS50009"
FT REGION 1..34
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 55..78
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 182..247
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 543..675
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 765..810
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 921..997
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1153..1176
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1244..1317
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..30
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 186..242
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 547..566
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 567..581
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 582..617
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 765..786
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 957..972
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 976..997
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1266..1288
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1698 AA; 188178 MW; F1F0B2390C60BE56 CRC64;
MQSQFRHVER TPLTPVQSEG KTSGIFTGRA ENGSQVKLPH NHALRSEKHA FGQLHTTSKG
GTMQNKSPPA NGRQTTNSLR RIKNSSEVLR QKALKRSNTI DVTPEGIGNA MLGGREARNF
TVGNVGHNGK MYLRPTNQSR SQLLPLTRAP TVPSNKQFLH PETNQEDNAR WARHSMWSNS
QLSELRPHMV REDSNESKYD ISKTPDDQGS RRHSLDEIPS SDSRNRKELR IVIERPESER
PKSADQTPVP AIEVPIPHFR LGGFRFTPGG KPTLRSSAYT RTSVSEHFRS STSTGYDSGT
APRASQLLNQ GSKTPRTYSV VPSVYTGPRA FSELPATVPA PSVFYKLREP IEPSIFDFLV
HIMDDPSVVR YVKGSNEISA ATPARIVAQI SSDSFMDYEL VSDFFLTFRS YLSPSNLLSL
LLARLQWAIN RPEEDGRIIR IRTFAALRHW ILNYFVDDFV VNRDLRVQFC QRLNQIYENV
RSCSNNSASD LKILLDLKRC WNGRCALYWD SPTFVNDSHP DDKVAPGGVA GSRDARLSRL
SDIHAPSHIV ESQTDNTVSH YPASPSKSIH HNEKDTRYFH PHTRNFSTAS DQNLPPSSES
VKSLQAASCS FPSKGQKRGS VHSPRPKGPH PVLVASSQRP SPTSPRPSTA AMIPAWRRPA
HSHKRSGSFS DSVRDDRAPL PALNLDNQGQ FLLQALPYAE SIIRGNVYAP VDPSVPTIAP
ASPTIEVAAQ VNFLRSETAT KVENYAKSAP GVKTLIGTIR RALHNRQSGN SSSPHATNTS
PLPSLKGKTS ALPLNVGVGS DTYRERRSGP DARAIPRIDV LCNDALQRYR QLVLRESLKS
GTVSEIAAAE EQEKDRSPMP VDRLNPESQF RFGLGLDRIP SQLTTGSKSI VIVDDTRFDI
PLMSGALHTI CNMPSQFQAP PLHNSEEAVD ASSPISHPDT LMGAPGPSLE RFDSNSVPTT
RDSRHSEEYV RLSGKRSSSM VRSGSKTPVQ TRSSSRLRKY ASYHSGMIKF GKHSSIGSTS
ELASGCGSSR GSREKPLARM LRRRPGGDLR KIQNAHDLQA GPRVRSFVSG TSYTESITES
VLYMNGDGTA GTPSNENHDR QDVLLPMERY SVVGAPPSQH VRVSFEAAVA GFSKIPDDED
GGIESTLLKL EGRWEKPLPA TPQDPEDQSY SSHDRTDKHW GRMEKFNHHQ HPAEPSIVPV
FQSDNGQQLA VNTAPDTESF AGSEDSYCSI PLLERGLSDE SMKSPVFNQS IPVPQPLFSP
NDEPATDKLE SSHPSIDMVE ETESLKRIRQ GSRPPTLPSS SRKPNYEDVG DDDYGSELSS
EISVIEKDEE VDRHYGRSAT TDVNASFPGL GVLSHPLTHP PSPPMTVQYP GSASSYAAPV
DAVTYHRQPI TPDLSPNCKN MPNTITQRSL DMNHLSSNVL SSSETQTYVQ GAPTMVSSNY
HHLPFILGCE SLTLAQQFTL VEKAALNEVD WKDLVDMRWS QSSQSTLNWA DYLSHHDRRG
IDIVVARFNL MVKWAVSEVV LTRDITERAQ TITKLIHVAM HSRRLRNYST MLQITIALCS
VDCTRLTKTW ELVADGEKQL LKDMESLAQP IRNFQKLRLE METTNLQDGC VPFVGLYVQD
LTYNSQKPAQ IASTRDGEPL VNFERYRTAA TIVKSLLRLI DASTKYTFEP VYGVIERCLW
ISALSDEKIV GLSTALAQ
//
