ID   A0A1J9QKG3_9EURO        Unreviewed;       239 AA.
AC   A0A1J9QKG3;
DT   15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT   15-FEB-2017, sequence version 1.
DT   27-MAR-2024, entry version 30.
DE   RecName: Full=Vacuolar protein sorting-associated protein 28 {ECO:0000256|PIRNR:PIRNR017535};
DE   AltName: Full=ESCRT-I complex subunit VPS28 {ECO:0000256|PIRNR:PIRNR017535};
GN   ORFNames=ACJ73_07965 {ECO:0000313|EMBL:OJD20699.1};
OS   Blastomyces percursus.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Onygenales; Ajellomycetaceae; Blastomyces.
OX   NCBI_TaxID=1658174 {ECO:0000313|EMBL:OJD20699.1, ECO:0000313|Proteomes:UP000242791};
RN   [1] {ECO:0000313|EMBL:OJD20699.1, ECO:0000313|Proteomes:UP000242791}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=EI222 {ECO:0000313|EMBL:OJD20699.1,
RC   ECO:0000313|Proteomes:UP000242791};
RA   Cuomo C.A., Schwartz I.S., Kenyon C., De Hoog G.S., Govender N.P.,
RA   Botha A., Moreno L., De Vries M., Munoz J.F., Stielow J.B.;
RT   "Emmonsia species relationships and genome sequence.";
RL   Submitted (AUG-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Component of the ESCRT-I complex (endosomal sorting complex
CC       required for transport I), a regulator of vesicular trafficking
CC       process. {ECO:0000256|PIRNR:PIRNR017535}.
CC   -!- SIMILARITY: Belongs to the VPS28 family.
CC       {ECO:0000256|PIRNR:PIRNR017535, ECO:0000256|PROSITE-ProRule:PRU00642}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OJD20699.1}.
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DR   EMBL; LGTZ01001745; OJD20699.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1J9QKG3; -.
DR   STRING; 1658174.A0A1J9QKG3; -.
DR   VEuPathDB; FungiDB:ACJ73_07965; -.
DR   OrthoDB; 5486880at2759; -.
DR   Proteomes; UP000242791; Unassembled WGS sequence.
DR   GO; GO:0000813; C:ESCRT I complex; IEA:UniProtKB-UniRule.
DR   GO; GO:0032509; P:endosome transport via multivesicular body sorting pathway; IEA:InterPro.
DR   GO; GO:0072666; P:establishment of protein localization to vacuole; IEA:UniProt.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-UniRule.
DR   GO; GO:0043162; P:ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway; IEA:UniProt.
DR   GO; GO:0007034; P:vacuolar transport; IEA:UniProt.
DR   Gene3D; 1.20.120.1130; -; 1.
DR   Gene3D; 1.20.1440.200; -; 1.
DR   InterPro; IPR037202; ESCRT_assembly_dom.
DR   InterPro; IPR007143; Vps28.
DR   InterPro; IPR017899; VPS28_C.
DR   InterPro; IPR037206; VPS28_C_sf.
DR   InterPro; IPR017898; VPS28_N.
DR   InterPro; IPR038358; VPS28_N_sf.
DR   PANTHER; PTHR12937; VACUOLAR PROTEIN SORTING 28, ISOFORM 2 VPS28; 1.
DR   PANTHER; PTHR12937:SF0; VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 28 HOMOLOG; 1.
DR   Pfam; PF03997; VPS28; 1.
DR   PIRSF; PIRSF017535; VPS28; 1.
DR   SUPFAM; SSF140111; Endosomal sorting complex assembly domain; 1.
DR   SUPFAM; SSF140427; VPS28 C-terminal domain-like; 1.
DR   PROSITE; PS51310; VPS28_C; 1.
DR   PROSITE; PS51313; VPS28_N; 1.
PE   3: Inferred from homology;
KW   Endosome {ECO:0000256|ARBA:ARBA00022753, ECO:0000256|PIRNR:PIRNR017535};
KW   Protein transport {ECO:0000256|ARBA:ARBA00022927,
KW   ECO:0000256|PIRNR:PIRNR017535};
KW   Reference proteome {ECO:0000313|Proteomes:UP000242791};
KW   Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|PIRNR:PIRNR017535}.
FT   DOMAIN          21..129
FT                   /note="VPS28 N-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS51313"
FT   DOMAIN          145..239
FT                   /note="VPS28 C-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS51310"
SQ   SEQUENCE   239 AA;  26718 MW;  79484C678DECA046 CRC64;
     MYQHRPLSYA PTPYSYTPNT ALSASINLDE EVKLSSTSAE RDLYESLAEI YSIILTLDGL
     EKAYIKDAIT ESEYTETCAR LLKQYKSSLS DETVAQEFVD LDTFRRTWGL ECPRATERLR
     IGVPVTVEQA SHSAAPAPSG PGTNASGSLI LAATENFITF LDALKLNMVS KDALHPLLSE
     IIQSVNRVTD QDFEHRGKII QWLIALNQMR ATEELSEDQA RELAFEIEQA YQGFKDTLS
//