ID A0A1J9QKY1_9EURO Unreviewed; 732 AA.
AC A0A1J9QKY1;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 13-SEP-2023, entry version 27.
DE RecName: Full=Alpha-actinin {ECO:0008006|Google:ProtNLM};
GN ORFNames=AJ78_03309 {ECO:0000313|EMBL:OJD16532.1};
OS Emergomyces pasteurianus Ep9510.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Ajellomycetaceae; Emergomyces.
OX NCBI_TaxID=1447872 {ECO:0000313|EMBL:OJD16532.1, ECO:0000313|Proteomes:UP000182235};
RN [1] {ECO:0000313|EMBL:OJD16532.1, ECO:0000313|Proteomes:UP000182235}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UAMH 9510 {ECO:0000313|EMBL:OJD16532.1,
RC ECO:0000313|Proteomes:UP000182235};
RG The Broad Institute Genomics Platform;
RA Cuomo C.A., Munoz J.F., Imamovic A., Priest M.E., Young S., Clay O.K.,
RA McEwen J.G.;
RT "Emmonsia species relationships and genome sequence.";
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the alpha-actinin family.
CC {ECO:0000256|ARBA:ARBA00010255}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OJD16532.1}.
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DR EMBL; LGRN01000103; OJD16532.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1J9QKY1; -.
DR STRING; 1447872.A0A1J9QKY1; -.
DR VEuPathDB; FungiDB:AJ78_03309; -.
DR OrthoDB; 2872403at2759; -.
DR Proteomes; UP000182235; Unassembled WGS sequence.
DR GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0016043; P:cellular component organization; IEA:UniProt.
DR CDD; cd21215; CH_SpAIN1-like_rpt1; 1.
DR CDD; cd21291; CH_SpAIN1-like_rpt2; 1.
DR CDD; cd00051; EFh; 1.
DR Gene3D; 1.20.58.60; -; 2.
DR Gene3D; 1.10.418.10; Calponin-like domain; 2.
DR Gene3D; 1.10.238.10; EF-hand; 2.
DR InterPro; IPR001589; Actinin_actin-bd_CS.
DR InterPro; IPR001715; CH_dom.
DR InterPro; IPR036872; CH_dom_sf.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR014837; EF-hand_Ca_insen.
DR InterPro; IPR002048; EF_hand_dom.
DR PANTHER; PTHR11915:SF435; SPECTRIN BETA CHAIN, NON-ERYTHROCYTIC 5; 1.
DR PANTHER; PTHR11915; SPECTRIN/FILAMIN RELATED CYTOSKELETAL PROTEIN; 1.
DR Pfam; PF00307; CH; 2.
DR Pfam; PF08726; EFhand_Ca_insen; 1.
DR SMART; SM00033; CH; 2.
DR SMART; SM01184; efhand_Ca_insen; 1.
DR SUPFAM; SSF47576; Calponin-homology domain, CH-domain; 1.
DR SUPFAM; SSF47473; EF-hand; 1.
DR SUPFAM; SSF46966; Spectrin repeat; 2.
DR PROSITE; PS00019; ACTININ_1; 1.
DR PROSITE; PS00020; ACTININ_2; 1.
DR PROSITE; PS50021; CH; 2.
DR PROSITE; PS50222; EF_HAND_2; 1.
PE 3: Inferred from homology;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203};
KW Reference proteome {ECO:0000313|Proteomes:UP000182235};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 91..196
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT DOMAIN 205..311
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT DOMAIN 565..600
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT REGION 1..35
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 713..732
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 732 AA; 83983 MW; CBC6D1C172874085 CRC64;
MPLPHPPQAI NHHHHHHPSS SSFSSHYPPP QSRHLHNHYA VFPNRTPNRT SSPYHCLDSN
SYFYPQRVGA GIGFAIPDRV MLLTEEKQWI TVQQKTFTKW LNNKLKVRDL AIDDLVKDLS
DGVILIHILE ILGNESLGRY ASKPKLRVQK FENANKSLDY VKGRGIPMTN IGAEDIVDGN
RKIILGLIWT LILRFTISDI SEEGMTAKEG LLLWCQRKTA CYPGVEVRDF SASWNDGLAF
CALLDIHRPD LIDFDSLDKN DHKGNMQLAF DIASNDIGIP DLLDVEDVCD VAKPDERSLM
TYIAYWFHAF SQLERVENAG RRVEKFVINM QGAWEMQNSF ERRMKELLQA IRAQRAEWHK
SSFEGTYADA KEQARKFGAY KRNQKRKWVA EKSDLAALLG NIKTKLSTYR LRAYEPPSEL
RLEVLDQEWS ALTQNERERS QLINETIRDI KNALRRSFAD KANDFALTLN TLSLAISGLE
GDVEDQLSHV KRLNDNLPPL DAFLETIAEL EERCIEANIE ENDFTTYTYD ELAYELGLVK
SSVSKKLAFL ENQTVARNMT NLTPIQLEEF ESVFRHFDRD SSNTLHEIEF SAALASLGLV
YDEDEMHEVF LETCGPARVE RNAGVSFEQF IRFMVSVTED QNTAEQVFQS FKEVADGKPY
VTELDLRHSL IPEELIDNLL QSMPRHNGPD LLEDRDLPKY DYITFMEKMM DVDGDDEDER
GESNNSRLVN GI
//
