ID   A0A1J9QQ89_9EURO        Unreviewed;       421 AA.
AC   A0A1J9QQ89;
DT   15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT   15-FEB-2017, sequence version 1.
DT   27-MAR-2024, entry version 17.
DE   RecName: Full=3-beta hydroxysteroid dehydrogenase/isomerase domain-containing protein {ECO:0000259|Pfam:PF01073};
GN   ORFNames=AJ78_02495 {ECO:0000313|EMBL:OJD17421.1};
OS   Emergomyces pasteurianus Ep9510.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Onygenales; Ajellomycetaceae; Emergomyces.
OX   NCBI_TaxID=1447872 {ECO:0000313|EMBL:OJD17421.1, ECO:0000313|Proteomes:UP000182235};
RN   [1] {ECO:0000313|EMBL:OJD17421.1, ECO:0000313|Proteomes:UP000182235}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=UAMH 9510 {ECO:0000313|EMBL:OJD17421.1,
RC   ECO:0000313|Proteomes:UP000182235};
RG   The Broad Institute Genomics Platform;
RA   Cuomo C.A., Munoz J.F., Imamovic A., Priest M.E., Young S., Clay O.K.,
RA   McEwen J.G.;
RT   "Emmonsia species relationships and genome sequence.";
RL   Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC       {ECO:0000256|ARBA:ARBA00004406}; Peripheral membrane protein
CC       {ECO:0000256|ARBA:ARBA00004406}.
CC   -!- SIMILARITY: Belongs to the 3-beta-HSD family.
CC       {ECO:0000256|ARBA:ARBA00009219}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OJD17421.1}.
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DR   EMBL; LGRN01000068; OJD17421.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1J9QQ89; -.
DR   STRING; 1447872.A0A1J9QQ89; -.
DR   VEuPathDB; FungiDB:AJ78_02495; -.
DR   OrthoDB; 1133at2759; -.
DR   Proteomes; UP000182235; Unassembled WGS sequence.
DR   GO; GO:0003854; F:3-beta-hydroxy-delta5-steroid dehydrogenase activity; IEA:InterPro.
DR   GO; GO:0006694; P:steroid biosynthetic process; IEA:InterPro.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR002225; 3Beta_OHSteriod_DH/Estase.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   PANTHER; PTHR43245; BIFUNCTIONAL POLYMYXIN RESISTANCE PROTEIN ARNA; 1.
DR   PANTHER; PTHR43245:SF51; SHORT CHAIN DEHYDROGENASE_REDUCTASE FAMILY 42E, MEMBER 2; 1.
DR   Pfam; PF01073; 3Beta_HSD; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000182235}.
FT   DOMAIN          92..331
FT                   /note="3-beta hydroxysteroid dehydrogenase/isomerase"
FT                   /evidence="ECO:0000259|Pfam:PF01073"
SQ   SEQUENCE   421 AA;  46446 MW;  C5C7C1D5DDF39585 CRC64;
     MATPTTLELG SVLVTGGCGF LGSHVVDQLL NFPSEAGRAE KGQVLQSPIR KPTGEPDTRF
     AVPRLAGRYP TYKNTKVSVL DLRTAHNRYP GADYYEADIM SVEQLLEVFR KVKPDVVIHT
     VSPPPMQSEP ELLYRINVDG TKNLLEVAGG MKGGWGGVCK AFVYTSSSSV VHDCHSDLIR
     ADERWPLITG KLQYEYYTET KAQAETLVLD FNKTSPTGML TTSIRPAGIY GERDTTLTKG
     LTDHARKSSP FVLRFQLGEN DNLFDFTYAG NVAYAHMLAA QCLLATFKRI ESGAAVPLDH
     ERVDGEAFNV TNDSPVYFWD MARSVWALMG KIVEPEKAIA LPEGALTVIG GLLEMAFGLF
     GKKPRMSRKE VRFSCMTRYY SCEKAKERIG YVPVVPLEEG VVRSVGTVLE REQGAEAKKA
     L
//