ID A0A1J9QWJ6_9EURO Unreviewed; 737 AA.
AC A0A1J9QWJ6;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=Homeobox domain-containing protein {ECO:0000259|PROSITE:PS50071};
GN ORFNames=ACJ73_04035 {ECO:0000313|EMBL:OJD24603.1};
OS Blastomyces percursus.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Ajellomycetaceae; Blastomyces.
OX NCBI_TaxID=1658174 {ECO:0000313|EMBL:OJD24603.1, ECO:0000313|Proteomes:UP000242791};
RN [1] {ECO:0000313|EMBL:OJD24603.1, ECO:0000313|Proteomes:UP000242791}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=EI222 {ECO:0000313|EMBL:OJD24603.1,
RC ECO:0000313|Proteomes:UP000242791};
RA Cuomo C.A., Schwartz I.S., Kenyon C., De Hoog G.S., Govender N.P.,
RA Botha A., Moreno L., De Vries M., Munoz J.F., Stielow J.B.;
RT "Emmonsia species relationships and genome sequence.";
RL Submitted (AUG-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PROSITE-ProRule:PRU00108, ECO:0000256|RuleBase:RU000682}.
CC -!- SIMILARITY: Belongs to the engrailed homeobox family.
CC {ECO:0000256|ARBA:ARBA00010896}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OJD24603.1}.
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DR EMBL; LGTZ01000528; OJD24603.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1J9QWJ6; -.
DR STRING; 1658174.A0A1J9QWJ6; -.
DR VEuPathDB; FungiDB:ACJ73_04035; -.
DR OrthoDB; 4638766at2759; -.
DR Proteomes; UP000242791; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:InterPro.
DR CDD; cd00086; homeodomain; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR017970; Homeobox_CS.
DR InterPro; IPR001356; Homeobox_dom.
DR PANTHER; PTHR24341; HOMEOBOX PROTEIN ENGRAILED; 1.
DR PANTHER; PTHR24341:SF6; HOMEOBOX PROTEIN INVECTED-RELATED; 1.
DR Pfam; PF00046; Homeodomain; 1.
DR SMART; SM00389; HOX; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR PROSITE; PS00027; HOMEOBOX_1; 1.
DR PROSITE; PS50071; HOMEOBOX_2; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00108};
KW Homeobox {ECO:0000256|ARBA:ARBA00023155, ECO:0000256|PROSITE-
KW ProRule:PRU00108};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00108}; Reference proteome {ECO:0000313|Proteomes:UP000242791}.
FT DOMAIN 64..124
FT /note="Homeobox"
FT /evidence="ECO:0000259|PROSITE:PS50071"
FT DNA_BIND 66..125
FT /note="Homeobox"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00108"
FT REGION 117..254
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 464..483
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 676..696
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 708..737
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 121..157
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 158..224
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 231..254
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 723..737
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 737 AA; 82454 MW; D0962DF0A5EA89CC CRC64;
MSYLHHPFPF GGHAIPVDQP VGYGVPIRHP QLGPSVDTYL LPNAPIDLAE YYRQTSLLED
FEEYTENLSR PRLTKEQVDT LEAQFQAHPK PNSNVKRQLA AQTNLTLPRV ANWFQNRRAK
AKQQKRQEEF ERMQASEKGE HWKINEDPQK EGEPKQQSEP LESSTSPTQQ PDSTSSSSIP
LSPAKQEKQQ QAFDSTAKSG RPESPQKAMN VAMPSSTQFN QPRENSDPYR HESSGITYHL
SQSPAGKNDD REFTSSLSRW NGMEENHAIW PSPQRAEDNF DFSHSNRHHG NPLEIRVQGS
PHFPTIQFNH EPDGWGCNSM PHLVEEQRHN SQDPGDCFYQ IPSHALQSPL YTEEPRRGSY
SSEQSELADT LYHTEIINNV IELSPQNTPH LNLAQLHHQV EPSTNWRYPD KEVDIAGRRK
RPRPAAIGIS SMSRSYGSSS MSPTTRIHGM GAGHVLRHAK STQNLSPNHT SRYPGIRKAS
APQRSPLGIT SFAEASRFNC ANTTDMMSTV PGLVTTTLAP PTPLTPEDLR TLLPPTPNDS
QYCVSPTDDM GCVRFFPMSQ PMQVHIESPP TTPLHLGVPP HLQYQSMGVP MSASSQHITF
QQYALSVPTN QMNSGLWPNV CSMSSPETSH LQQPTIHMPQ PTHISPIAYE ESLDSGNPAL
VEDTVTSQNE LPQCTVKSCG MPTTSSPQGS TPGSQKVTEF LIQEFPEQQE AHRRAAEQLP
PQKPMNYTFS NHTPNDF
//
