ID   A0A1J9R6G3_9EURO        Unreviewed;       875 AA.
AC   A0A1J9R6G3;
DT   15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT   15-FEB-2017, sequence version 1.
DT   27-MAR-2024, entry version 33.
DE   RecName: Full=RING-type domain-containing protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=ACJ73_05431 {ECO:0000313|EMBL:OJD23221.1};
OS   Blastomyces percursus.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Onygenales; Ajellomycetaceae; Blastomyces.
OX   NCBI_TaxID=1658174 {ECO:0000313|EMBL:OJD23221.1, ECO:0000313|Proteomes:UP000242791};
RN   [1] {ECO:0000313|EMBL:OJD23221.1, ECO:0000313|Proteomes:UP000242791}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=EI222 {ECO:0000313|EMBL:OJD23221.1,
RC   ECO:0000313|Proteomes:UP000242791};
RA   Cuomo C.A., Schwartz I.S., Kenyon C., De Hoog G.S., Govender N.P.,
RA   Botha A., Moreno L., De Vries M., Munoz J.F., Stielow J.B.;
RT   "Emmonsia species relationships and genome sequence.";
RL   Submitted (AUG-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OJD23221.1}.
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DR   EMBL; LGTZ01000848; OJD23221.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1J9R6G3; -.
DR   STRING; 1658174.A0A1J9R6G3; -.
DR   VEuPathDB; FungiDB:ACJ73_05431; -.
DR   OrthoDB; 1752784at2759; -.
DR   Proteomes; UP000242791; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0046486; P:glycerolipid metabolic process; IEA:UniProt.
DR   GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-UniRule.
DR   CDD; cd07199; Pat17_PNPLA8_PNPLA9_like; 1.
DR   Gene3D; 3.40.1090.10; Cytosolic phospholipase A2 catalytic domain; 1.
DR   InterPro; IPR016035; Acyl_Trfase/lysoPLipase.
DR   InterPro; IPR002641; PNPLA_dom.
DR   InterPro; IPR001841; Znf_RING.
DR   InterPro; IPR017907; Znf_RING_CS.
DR   PANTHER; PTHR24185; CALCIUM-INDEPENDENT PHOSPHOLIPASE A2-GAMMA; 1.
DR   PANTHER; PTHR24185:SF1; CALCIUM-INDEPENDENT PHOSPHOLIPASE A2-GAMMA; 1.
DR   Pfam; PF01734; Patatin; 1.
DR   SUPFAM; SSF52151; FabD/lysophospholipase-like; 1.
DR   SUPFAM; SSF57850; RING/U-box; 1.
DR   PROSITE; PS51635; PNPLA; 1.
DR   PROSITE; PS00518; ZF_RING_1; 1.
DR   PROSITE; PS50089; ZF_RING_2; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Lipid degradation {ECO:0000256|ARBA:ARBA00022963};
KW   Lipid metabolism {ECO:0000256|ARBA:ARBA00023098};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000242791};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW   ProRule:PRU00175}.
FT   DOMAIN          327..373
FT                   /note="RING-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50089"
FT   DOMAIN          392..604
FT                   /note="PNPLA"
FT                   /evidence="ECO:0000259|PROSITE:PS51635"
SQ   SEQUENCE   875 AA;  97998 MW;  178594700F622840 CRC64;
     MAHYGNFAGP IIVEVASGSG MVQIYKRTTF LSSPPIPEFL QTAIQRAARR RTHQAAPRHA
     TAMRAYQSSG LTPHDVGGLE AVQSLLMKWA TIGSASTLPD TIRPRIIVVT GKDNDSITQA
     LLNEEFFLLD IANDALFHSA FADISISRHP PGELFPDARY LDLHADIARE LHLARSARKI
     HQVLFSATHM NAFYEDGLRH VTANMFTPFD FIHASRRLNP VSGSLVPHLS TVLNQGVNKR
     MPYEDLVSYT ASAILMDAYP PLMHGIAYEQ VLGNCALADL MCQNVDHQLE RLFEFMSMKG
     DSSSHIHRYN LNQRRKHLAL LRLNSVCLVC VIRCAEYRLP CGHALCDSCV ERFGEGCAGA
     ESEYVVTTCP LCNTPTALKV RVKPSTFAAR LFSIDGGGLL GIIPAELLVF MQKRLLCNLQ
     LRNLIDYFIG TSSGGDISLD IGICQNGAEK CSERFQQLAK GFFGGQQRGC VSKLRRLAKI
     WTADGMYDSR ALEHVFRQHY GATLRMFDTP RTMIAGWRVA VTSTSVADGT PFLFTNYNGE
     TPLRNDCVYG CLRTMVDDEP FVWQAARATS AAPVLFPSID IPSVGSFQDG GMKQRHNNPI
     RSGLSEVRRL WPRTPKPHVV ISLGTGTVSR ALKTSDSRNI LLDGWLPRIY RSYMSSFDGE
     ETWNELQGEL DDQTSKNYFR LNYSFTGARP SIVDISAMEN ISRSIQKNPP AADKMEEALL
     TLLASSLFFE LDSIPEFQNG FFRCVGTIRC YGPTRPIIRS LLALRPAHHE FYKDDINLGL
     YLSEDDICVE FQRYCQPVRF SVRHLQEKIT MTLRSDGTAL LLNGFPNATQ WYIDEQGLDG
     VFGASNHGAP FRIQCDTCER RLNGKEKKRK YMYTR
//