ID A0A1J9R7B9_9PEZI Unreviewed; 307 AA.
AC A0A1J9R7B9;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=6-phosphogluconate dehydrogenase 2 {ECO:0000313|EMBL:OJD37422.1};
GN ORFNames=BKCO1_7000167 {ECO:0000313|EMBL:OJD37422.1};
OS Diplodia corticola.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Dothideomycetes incertae sedis; Botryosphaeriales; Botryosphaeriaceae;
OC Diplodia.
OX NCBI_TaxID=236234 {ECO:0000313|EMBL:OJD37422.1, ECO:0000313|Proteomes:UP000183809};
RN [1] {ECO:0000313|EMBL:OJD37422.1, ECO:0000313|Proteomes:UP000183809}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 112549 {ECO:0000313|EMBL:OJD37422.1,
RC ECO:0000313|Proteomes:UP000183809};
RA Fernandes I., De Jonge R., Van De Peer Y., Devreese B., Alves A.,
RA Esteves A.C.;
RT "Proteomics and genomics reveal pathogen-plant mechanisms compatible with a
RT hemibiotrophic lifestyle of Diplodia corticola.";
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the HIBADH-related family. NP60 subfamily.
CC {ECO:0000256|ARBA:ARBA00007598}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OJD37422.1}.
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DR EMBL; MNUE01000007; OJD37422.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1J9R7B9; -.
DR STRING; 236234.A0A1J9R7B9; -.
DR OrthoDB; 2715114at2759; -.
DR Proteomes; UP000183809; Unassembled WGS sequence.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR GO; GO:0050661; F:NADP binding; IEA:InterPro.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR013328; 6PGD_dom2.
DR InterPro; IPR006115; 6PGDH_NADP-bd.
DR InterPro; IPR029154; HIBADH-like_NADP-bd.
DR InterPro; IPR015815; HIBADH-related.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR43580:SF3; 6-PHOSPHOGLUCONATE DEHYDROGENASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_2G11600); 1.
DR PANTHER; PTHR43580; OXIDOREDUCTASE GLYR1-RELATED; 1.
DR Pfam; PF14833; NAD_binding_11; 1.
DR Pfam; PF03446; NAD_binding_2; 1.
DR PIRSF; PIRSF000103; HIBADH; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 3: Inferred from homology;
KW NAD {ECO:0000256|ARBA:ARBA00023027};
KW Reference proteome {ECO:0000313|Proteomes:UP000183809}.
FT DOMAIN 5..156
FT /note="6-phosphogluconate dehydrogenase NADP-binding"
FT /evidence="ECO:0000259|Pfam:PF03446"
FT DOMAIN 173..292
FT /note="3-hydroxyisobutyrate dehydrogenase-like NAD-binding"
FT /evidence="ECO:0000259|Pfam:PF14833"
FT ACT_SITE 179
FT /evidence="ECO:0000256|PIRSR:PIRSR000103-1"
SQ SEQUENCE 307 AA; 32625 MW; 33E6996CE6254CE4 CRC64;
MAPQLAWIGL GNMGRGMCSN LVEKGNLEKP LIIYNRTKKR ADDLSTKLPS GKSTVVSSVE
DTVRQADIIF TCVGDDKAIN ETIDSALAGD VNGKLFVDCS TVHPETTDAL ATRISSKGAG
FVAGPVFGAP AMADAGQLIF VLAGEAPWVE KAKPYTTGVM GKAIIDFSGQ AHGKATLLKV
IGNTFIFNMI EALSVGHTLA EKSGLGTDNL HQFIETMFPG PYTAYSNRMR SGDYYKREEP
LFQVDLARKD ARHALSLAES SGAKLRAVEV IDSHLEGVQK ACGAKGDVAG IYGAVRQESG
LPFENGP
//
