ID A0A1J9RC66_9EURO Unreviewed; 955 AA.
AC A0A1J9RC66;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 13-SEP-2023, entry version 23.
DE RecName: Full=SPX domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=ACJ73_03048 {ECO:0000313|EMBL:OJD25580.1};
OS Blastomyces percursus.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Ajellomycetaceae; Blastomyces.
OX NCBI_TaxID=1658174 {ECO:0000313|EMBL:OJD25580.1, ECO:0000313|Proteomes:UP000242791};
RN [1] {ECO:0000313|EMBL:OJD25580.1, ECO:0000313|Proteomes:UP000242791}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=EI222 {ECO:0000313|EMBL:OJD25580.1,
RC ECO:0000313|Proteomes:UP000242791};
RA Cuomo C.A., Schwartz I.S., Kenyon C., De Hoog G.S., Govender N.P.,
RA Botha A., Moreno L., De Vries M., Munoz J.F., Stielow J.B.;
RT "Emmonsia species relationships and genome sequence.";
RL Submitted (AUG-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the SYG1 (TC 2.A.94) family.
CC {ECO:0000256|ARBA:ARBA00009665}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OJD25580.1}.
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DR EMBL; LGTZ01000350; OJD25580.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1J9RC66; -.
DR STRING; 1658174.A0A1J9RC66; -.
DR VEuPathDB; FungiDB:ACJ73_03048; -.
DR OrthoDB; 7162at2759; -.
DR Proteomes; UP000242791; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR CDD; cd14475; SPX_SYG1_like; 1.
DR InterPro; IPR004342; EXS_C.
DR InterPro; IPR004331; SPX_dom.
DR PANTHER; PTHR10783:SF103; XENOTROPIC AND POLYTROPIC RETROVIRUS RECEPTOR 1; 1.
DR PANTHER; PTHR10783; XENOTROPIC AND POLYTROPIC RETROVIRUS RECEPTOR 1-RELATED; 1.
DR Pfam; PF03124; EXS; 2.
DR Pfam; PF03105; SPX; 1.
DR PROSITE; PS51380; EXS; 1.
DR PROSITE; PS51382; SPX; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000242791};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 502..520
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 540..560
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1..447
FT /note="SPX"
FT /evidence="ECO:0000259|PROSITE:PS51382"
FT DOMAIN 639..833
FT /note="EXS"
FT /evidence="ECO:0000259|PROSITE:PS51380"
FT REGION 62..175
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 201..223
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 844..878
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 893..955
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 123..141
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 844..860
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 894..926
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 927..945
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 955 AA; 109688 MW; B21B316597F7D35B CRC64;
MKFAKELEED LVPEWRAKFL NYKAGKKKVK AISRALRQAE QQSPFAHRRR LSQIFQHEDR
PSFDFPRSHS LSHQASPLAR AQKSPAFLER PEPALRDPSG GKYGDTLPVV VVPERRPLKS
PGSRFNEQPS SYGSIVASPP QHVSPSIPPS LELPGPALDL EDPHPRPGTS VRSIPWSGVD
ATRSIKAAGD AAGNGTVELT NTRSENSTSC NPRETSNVGL LRGHSVPSRV LNNQKARLKN
VFTSRTHSDH TIMRGPVDAS MALKHKESEF FAFLDKELAK IESFYHMKEK EASERLAVLR
SQLHLMRDTR VAEIRTNKRN LEVKARLVAS KSDTAASVMK WKTPLGDKLN NARSRKTSKA
MEQLATPAGP VPMNSHPDEQ RDFVRHEDLY DVSYRSAKRK LKIALLEFYR GLELLKAYAD
LNRKAFRKMN KKYDKVTGTR PTGRYVSEKV NKAWFVQSEV VENHMVSVED LYTRYFERGN
RKVAVRKLRG KASRTYDYSS NAFRNGLMLA GGVAFGVHGL THAVRRLFYG DSEIRLYTAY
LLQIYGGYFL AVFHFLLFCL DCKIWGASKI NYAFVFEFDT RHALDWRQLS EWRLLLAGFY
PVEFRDFFLG DMYCSQTYAM SNISLFFCLY SKGWDDAPRC NSSHSRVMGF LSTVPSIWRS
FQCIRRYLDT KNVFPHIVNL GKYSFSILYY MTLSLYRIHK VDELRAIFIT CACINAIYTS
IWDLAMDWSL GNPYSKHPFL RDSLAFRRRW VYYVAMAIDP ILRFNWIFYA ISPHDYQHSA
ILSFILSFSE VCRRGMWSIF RVENEHCTNV ARFRASRDVP LPYEIPSPAR TSVERLEEQY
NPLRQGSLLD NSQTATGVDL ENRPCSIRQR KMPTPPELTR TLSRVGTMVA NAHAQDFERR
KQPGILNDTS KDELSSSRHV RENSSTDEEA EEDDEEYDEE NDEEHAFQDA ERVVS
//
