ID A0A1K0GRP3_9ACTN Unreviewed; 970 AA.
AC A0A1K0GRP3;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 24-JAN-2024, entry version 26.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:OJF15094.1};
GN ORFNames=BG844_06475 {ECO:0000313|EMBL:OJF15094.1};
OS Couchioplanes caeruleus subsp. caeruleus.
OC Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC Micromonosporaceae; Couchioplanes.
OX NCBI_TaxID=56427 {ECO:0000313|EMBL:OJF15094.1, ECO:0000313|Proteomes:UP000182486};
RN [1] {ECO:0000313|EMBL:OJF15094.1, ECO:0000313|Proteomes:UP000182486}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 43634 {ECO:0000313|EMBL:OJF15094.1,
RC ECO:0000313|Proteomes:UP000182486};
RA Sheehan J., Caffrey P.;
RT "Couchioplanes caeruleus draft genome sequence.";
RL Submitted (SEP-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OJF15094.1}.
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DR EMBL; MEIA01000069; OJF15094.1; -; Genomic_DNA.
DR RefSeq; WP_071803821.1; NZ_MEIA01000069.1.
DR AlphaFoldDB; A0A1K0GRP3; -.
DR Proteomes; UP000182486; Unassembled WGS sequence.
DR GO; GO:0004315; F:3-oxoacyl-[acyl-carrier-protein] synthase activity; IEA:InterPro.
DR GO; GO:0006633; P:fatty acid biosynthetic process; IEA:InterPro.
DR CDD; cd00833; PKS; 1.
DR Gene3D; 3.30.70.3290; -; 1.
DR Gene3D; 3.40.47.10; -; 1.
DR Gene3D; 1.10.1200.10; ACP-like; 1.
DR Gene3D; 3.40.366.10; Malonyl-Coenzyme A Acyl Carrier Protein, domain 2; 1.
DR InterPro; IPR001227; Ac_transferase_dom_sf.
DR InterPro; IPR036736; ACP-like_sf.
DR InterPro; IPR014043; Acyl_transferase.
DR InterPro; IPR016035; Acyl_Trfase/lysoPLipase.
DR InterPro; IPR018201; Ketoacyl_synth_AS.
DR InterPro; IPR014031; Ketoacyl_synth_C.
DR InterPro; IPR014030; Ketoacyl_synth_N.
DR InterPro; IPR016036; Malonyl_transacylase_ACP-bd.
DR InterPro; IPR032821; PKS_assoc.
DR InterPro; IPR020841; PKS_Beta-ketoAc_synthase_dom.
DR InterPro; IPR009081; PP-bd_ACP.
DR InterPro; IPR006162; Ppantetheine_attach_site.
DR InterPro; IPR016039; Thiolase-like.
DR PANTHER; PTHR43775; FATTY ACID SYNTHASE; 1.
DR PANTHER; PTHR43775:SF37; FATTY ACID SYNTHASE; 1.
DR Pfam; PF00698; Acyl_transf_1; 1.
DR Pfam; PF16197; KAsynt_C_assoc; 1.
DR Pfam; PF00109; ketoacyl-synt; 1.
DR Pfam; PF02801; Ketoacyl-synt_C; 1.
DR Pfam; PF00550; PP-binding; 1.
DR SMART; SM00827; PKS_AT; 1.
DR SMART; SM00825; PKS_KS; 1.
DR SUPFAM; SSF47336; ACP-like; 1.
DR SUPFAM; SSF52151; FabD/lysophospholipase-like; 1.
DR SUPFAM; SSF55048; Probable ACP-binding domain of malonyl-CoA ACP transacylase; 1.
DR SUPFAM; SSF53901; Thiolase-like; 1.
DR PROSITE; PS50075; CARRIER; 1.
DR PROSITE; PS00606; KS3_1; 1.
DR PROSITE; PS52004; KS3_2; 1.
DR PROSITE; PS00012; PHOSPHOPANTETHEINE; 1.
PE 4: Predicted;
KW Phosphopantetheine {ECO:0000256|ARBA:ARBA00022450};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000182486};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 2..438
FT /note="Ketosynthase family 3 (KS3)"
FT /evidence="ECO:0000259|PROSITE:PS52004"
FT DOMAIN 897..970
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
SQ SEQUENCE 970 AA; 102003 MW; 1F177EB8F1E21A05 CRC64;
MNGDIAIVGM AGRFPGAADV GEFWSHVVAG RITVSELTRG ELLAAGVRAD RLDDPAYVPA
RGVLADLELF DAAFFGITPR DAEIMDPQHR LLMQTAWAAL ESAGLATDRP FGRVGVFAGA
GFNYYALHHV FTRPDLVDTQ GLLSVVLGNE KDHLATKIAY RLNLGGPAVT VQTACSTSLV
AVHLACQSLR TGDADVALAG GACVAVPQQE GYLYETKGIM SPDGACRPFD ASANGTVPGN
GVAMVALKRA EDARRDGDTV YALIKGSAVN NDGGMKVGYT APGIAGQVDV LERAYAAAGV
DPATVGYLEA HGTATEVGDA IELSALTEVF RRGAHVTDLQ EFSAAGGLCS IGSVKANVGH
LDAAAGVTAL IKAALALHLR QIPPLAGLKQ ARPELLDGST PFTVDSVARR WDSTGGPRRA
GVSSFGLGGT NAHVVLEEAD AVAVPGPPAA GGRAELIVLS GRSPEVVREA AERWSDHLRQ
RPDLAVGDVA LTSQAYRRHF PHRLAVAATD LPTVLARLRR APVREAARRP SVVFLFPGQG
AEVPAMSRDL YDRYPSFRDD LDHGARLLEP VLRWDLRDVL VGTDPEGIVH RTDVTQPALA
LHELALGRLL MSWGVRPAAL IGHSVGEFAA AALAGEMAAD DMLRLVATRG ALMQDAPEGG
MLAVLAPLST VAAHLTGLDD LDLAAHNAPE STVVAGPVAQ LAVFRERLDA AEVRSRALPA
QRAFHSRMMA DAARLLAAEA ERIAQQPRSI PVVSSLDGEL LGRGSTRSEG YWSAQLRSPV
RYHDALLTAL GLPDPVLVEV GPGASLTGLA RQAPEGRSVP GLALQPRPSA RSGAGDVLNG
LGGLWTAGAA VDWAAVRGEN GARRIALPTY PFTRTRHWLD AAPAEAAADP APPPAATGED
EKVREIIDLW SRMLGTPEIG PEANFFALGG ESLQFIRMIT QVRRRFGVQI PVDELANDPT
PRTLAALVTP
//
