ID A0A1K0GRW3_9ACTN Unreviewed; 326 AA.
AC A0A1K0GRW3;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 24-JAN-2024, entry version 25.
DE RecName: Full=Probable cell division protein WhiA {ECO:0000256|HAMAP-Rule:MF_01420};
GN Name=whiA {ECO:0000256|HAMAP-Rule:MF_01420};
GN ORFNames=BG844_12265 {ECO:0000313|EMBL:OJF13956.1};
OS Couchioplanes caeruleus subsp. caeruleus.
OC Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC Micromonosporaceae; Couchioplanes.
OX NCBI_TaxID=56427 {ECO:0000313|EMBL:OJF13956.1, ECO:0000313|Proteomes:UP000182486};
RN [1] {ECO:0000313|EMBL:OJF13956.1, ECO:0000313|Proteomes:UP000182486}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 43634 {ECO:0000313|EMBL:OJF13956.1,
RC ECO:0000313|Proteomes:UP000182486};
RA Sheehan J., Caffrey P.;
RT "Couchioplanes caeruleus draft genome sequence.";
RL Submitted (SEP-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Involved in cell division and chromosome segregation.
CC {ECO:0000256|HAMAP-Rule:MF_01420}.
CC -!- SIMILARITY: Belongs to the WhiA family. {ECO:0000256|HAMAP-
CC Rule:MF_01420}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OJF13956.1}.
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DR EMBL; MEIA01000126; OJF13956.1; -; Genomic_DNA.
DR RefSeq; WP_071805306.1; NZ_MEIA01000126.1.
DR AlphaFoldDB; A0A1K0GRW3; -.
DR Proteomes; UP000182486; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-UniRule.
DR GO; GO:0043937; P:regulation of sporulation; IEA:InterPro.
DR Gene3D; 3.10.28.10; Homing endonucleases; 1.
DR HAMAP; MF_01420; HTH_type_WhiA; 1.
DR InterPro; IPR027434; Homing_endonucl.
DR InterPro; IPR018478; Sporu_reg_WhiA_N_dom.
DR InterPro; IPR003802; Sporulation_regulator_WhiA.
DR InterPro; IPR023054; Sporulation_regulator_WhiA_C.
DR InterPro; IPR039518; WhiA_LAGLIDADG_dom.
DR NCBIfam; TIGR00647; DNA_bind_WhiA; 1.
DR PANTHER; PTHR37307; CELL DIVISION PROTEIN WHIA-RELATED; 1.
DR PANTHER; PTHR37307:SF1; CELL DIVISION PROTEIN WHIA-RELATED; 1.
DR Pfam; PF02650; HTH_WhiA; 1.
DR Pfam; PF14527; LAGLIDADG_WhiA; 1.
DR Pfam; PF10298; WhiA_N; 1.
PE 3: Inferred from homology;
KW Cell cycle {ECO:0000256|ARBA:ARBA00023306, ECO:0000256|HAMAP-
KW Rule:MF_01420};
KW Cell division {ECO:0000256|ARBA:ARBA00022618, ECO:0000256|HAMAP-
KW Rule:MF_01420};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|HAMAP-
KW Rule:MF_01420}; Reference proteome {ECO:0000313|Proteomes:UP000182486}.
FT DOMAIN 19..104
FT /note="Sporulation transcription regulator WhiA N-terminal"
FT /evidence="ECO:0000259|Pfam:PF10298"
FT DOMAIN 128..218
FT /note="WhiA LAGLIDADG-like"
FT /evidence="ECO:0000259|Pfam:PF14527"
FT DOMAIN 221..303
FT /note="Sporulation regulator WhiA C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02650"
SQ SEQUENCE 326 AA; 34908 MW; 8F74044F2F4A72DD CRC64;
MAMTAAVKDE LSRVDVPKPC CRRAEMAALL RFAGGLHIVS GRVVVEAELD TGAVARRLRR
EIADVYGYPS EVHVLASGGL RKGSHYIVRI VKDGEALARQ TGLLDVRGRP VRGLPPHVVS
ANVCCAVAAW RGAFMAHGSL TEPGRSSALE ITCPGPEAAL ALRGAARRIG ITAKEREVRG
VDRVVIKDGD AIAALLTRVG AHASVLAWEE RRVRREVRAT ANRLANFDDA NLRRSARAAV
AAAARVTRAL EILADEAPNH LTSAGRLRLE HRQASLEELG ALADPPLTKD AIAGRIRRLL
ALADKRARDL GIPDTEAAVT PEMMAC
//
