ID   A0A1K1MJH7_9FIRM        Unreviewed;       114 AA.
AC   A0A1K1MJH7;
DT   15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT   15-FEB-2017, sequence version 1.
DT   27-MAR-2024, entry version 18.
DE   SubName: Full=Histidine triad (HIT) family protein {ECO:0000313|EMBL:SFW23243.1};
GN   ORFNames=SAMN02910447_00999 {ECO:0000313|EMBL:SFW23243.1};
OS   Ruminococcus sp. YE71.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae;
OC   Ruminococcus.
OX   NCBI_TaxID=244362 {ECO:0000313|EMBL:SFW23243.1, ECO:0000313|Proteomes:UP000182164};
RN   [1] {ECO:0000313|EMBL:SFW23243.1, ECO:0000313|Proteomes:UP000182164}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=YE71 {ECO:0000313|EMBL:SFW23243.1,
RC   ECO:0000313|Proteomes:UP000182164};
RA   Jaros S., Januszkiewicz K., Wedrychowicz H.;
RL   Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FPIR01000004; SFW23243.1; -; Genomic_DNA.
DR   RefSeq; WP_072417126.1; NZ_FPIR01000004.1.
DR   AlphaFoldDB; A0A1K1MJH7; -.
DR   STRING; 244362.SAMN02910447_00999; -.
DR   Proteomes; UP000182164; Unassembled WGS sequence.
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   CDD; cd01276; PKCI_related; 1.
DR   Gene3D; 3.30.428.10; HIT-like; 1.
DR   InterPro; IPR019808; Histidine_triad_CS.
DR   InterPro; IPR001310; Histidine_triad_HIT.
DR   InterPro; IPR011146; HIT-like.
DR   InterPro; IPR036265; HIT-like_sf.
DR   PANTHER; PTHR23089:SF33; ADENOSINE 5'-MONOPHOSPHORAMIDASE HINT1; 1.
DR   PANTHER; PTHR23089; HISTIDINE TRIAD HIT PROTEIN; 1.
DR   Pfam; PF01230; HIT; 1.
DR   PRINTS; PR00332; HISTRIAD.
DR   SUPFAM; SSF54197; HIT-like; 1.
DR   PROSITE; PS00892; HIT_1; 1.
DR   PROSITE; PS51084; HIT_2; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000182164}.
FT   DOMAIN          5..114
FT                   /note="HIT"
FT                   /evidence="ECO:0000259|PROSITE:PS51084"
FT   MOTIF           98..102
FT                   /note="Histidine triad motif"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR601310-3,
FT                   ECO:0000256|PROSITE-ProRule:PRU00464"
FT   ACT_SITE        100
FT                   /note="Tele-AMP-histidine intermediate"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR601310-1"
SQ   SEQUENCE   114 AA;  12697 MW;  02109D7B3445E86A CRC64;
     MNDCLFCKII AGEIPSTKIF EDEQVYVFAD IAPTAPIHWL VIPKTHIAKL SDITPENSAV
     IAHIYEVISK LAAEHEEFRD GFRVVTNCGE RAGQSVFHIH FHVLAGRDLA WPAG
//