ID A0A1K1NIP2_RUMFL Unreviewed; 251 AA.
AC A0A1K1NIP2;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 24-JAN-2024, entry version 16.
DE SubName: Full=Cobalt-precorrin 4 C11-methyltransferase {ECO:0000313|EMBL:SFW35196.1};
GN ORFNames=SAMN02910280_2046 {ECO:0000313|EMBL:SFW35196.1};
OS Ruminococcus flavefaciens.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae;
OC Ruminococcus.
OX NCBI_TaxID=1265 {ECO:0000313|EMBL:SFW35196.1, ECO:0000313|Proteomes:UP000183461};
RN [1] {ECO:0000313|EMBL:SFW35196.1, ECO:0000313|Proteomes:UP000183461}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=YL228 {ECO:0000313|EMBL:SFW35196.1,
RC ECO:0000313|Proteomes:UP000183461};
RA Jaros S., Januszkiewicz K., Wedrychowicz H.;
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the precorrin methyltransferase family.
CC {ECO:0000256|ARBA:ARBA00005879}.
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DR EMBL; FPIP01000004; SFW35196.1; -; Genomic_DNA.
DR RefSeq; WP_072300297.1; NZ_FPIP01000004.1.
DR AlphaFoldDB; A0A1K1NIP2; -.
DR Proteomes; UP000183461; Unassembled WGS sequence.
DR GO; GO:0046026; F:precorrin-4 C11-methyltransferase activity; IEA:InterPro.
DR GO; GO:0009236; P:cobalamin biosynthetic process; IEA:InterPro.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR CDD; cd11641; Precorrin-4_C11-MT; 1.
DR InterPro; IPR000878; 4pyrrol_Mease.
DR InterPro; IPR035996; 4pyrrol_Methylase_sf.
DR InterPro; IPR014777; 4pyrrole_Mease_sub1.
DR InterPro; IPR014776; 4pyrrole_Mease_sub2.
DR InterPro; IPR006362; Cbl_synth_CobM/CibF.
DR NCBIfam; TIGR01465; cobM_cbiF; 1.
DR PANTHER; PTHR45790:SF4; COBALT-PRECORRIN-4 C(11)-METHYLTRANSFERASE; 1.
DR PANTHER; PTHR45790; SIROHEME SYNTHASE-RELATED; 1.
DR Pfam; PF00590; TP_methylase; 1.
DR SUPFAM; SSF53790; Tetrapyrrole methylase; 1.
PE 3: Inferred from homology;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW ECO:0000313|EMBL:SFW35196.1};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:SFW35196.1}.
FT DOMAIN 1..207
FT /note="Tetrapyrrole methylase"
FT /evidence="ECO:0000259|Pfam:PF00590"
SQ SEQUENCE 251 AA; 26986 MW; 1F7AEA800EDC675D CRC64;
MVHFVGAGSG AADLITLRGK KLLEEADVVI YAGSLVNPEL LDYTKSGCEI YNSAVMTLDE
VIDVMEKAEN VGKTTVRLHT GDPCVYGAVR EQMDRLDKLG IDYDVCPGVS SFCGAAAALK
VEYTLPDVSQ TVILTRMAGR TPVPEKESIE SLAAHHATMV IFLSTGMLEE LSERLINGGY
STETPAAIVY KATWADEKVC RCTVGSLAET AAKNGITKTA LITVGDFLGD VRSLSKLYSA
DFETKFRKAS K
//
