ID   A0A1K1P293_9FIRM        Unreviewed;       225 AA.
AC   A0A1K1P293;
DT   15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT   15-FEB-2017, sequence version 1.
DT   24-JAN-2024, entry version 17.
DE   SubName: Full=Vitamin B12 dependent methionine synthase, activation domain {ECO:0000313|EMBL:SFW41692.1};
GN   ORFNames=SAMN02910447_02474 {ECO:0000313|EMBL:SFW41692.1};
OS   Ruminococcus sp. YE71.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae;
OC   Ruminococcus.
OX   NCBI_TaxID=244362 {ECO:0000313|EMBL:SFW41692.1, ECO:0000313|Proteomes:UP000182164};
RN   [1] {ECO:0000313|EMBL:SFW41692.1, ECO:0000313|Proteomes:UP000182164}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=YE71 {ECO:0000313|EMBL:SFW41692.1,
RC   ECO:0000313|Proteomes:UP000182164};
RA   Jaros S., Januszkiewicz K., Wedrychowicz H.;
RL   Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FPIR01000013; SFW41692.1; -; Genomic_DNA.
DR   RefSeq; WP_072418517.1; NZ_FPIR01000013.1.
DR   AlphaFoldDB; A0A1K1P293; -.
DR   STRING; 244362.SAMN02910447_02474; -.
DR   Proteomes; UP000182164; Unassembled WGS sequence.
DR   GO; GO:0008705; F:methionine synthase activity; IEA:InterPro.
DR   Gene3D; 3.40.109.40; -; 1.
DR   InterPro; IPR017342; S-AdoMet-dep_Met_synth_prd.
DR   InterPro; IPR004223; VitB12-dep_Met_synth_activ_dom.
DR   InterPro; IPR037010; VitB12-dep_Met_synth_activ_sf.
DR   Pfam; PF02965; Met_synt_B12; 1.
DR   PIRSF; PIRSF037984; Met_synth_TM0269_prd; 1.
DR   SUPFAM; SSF56507; Methionine synthase activation domain-like; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000182164}.
FT   DOMAIN          83..191
FT                   /note="AdoMet activation"
FT                   /evidence="ECO:0000259|Pfam:PF02965"
SQ   SEQUENCE   225 AA;  24855 MW;  EFB6CD6EE4795CCA CRC64;
     MPDSIRLKID IDEAIRYMGY REAPNKQQLE TIRGLAELIE KDTKPAWVYR VFPIIETEDG
     IELKGTKLVL TGSSVRKHLK GCDSAVLLCA TISAKADEII RQKEREDIAL GFMTDCLASA
     AVESICNEIE RMLAEKFSTK FFTWRFSPGY GDLPLDVQPY IIEVLGAGKR AGVTCTPSLM
     MIPSKSVTAV IGLSDVPIDR GRRGCAVCNL SGTCEFRKRG VRCGT
//