ID   A0A1K1RLX2_9PSEU        Unreviewed;       392 AA.
AC   A0A1K1RLX2;
DT   15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT   15-FEB-2017, sequence version 1.
DT   27-MAR-2024, entry version 18.
DE   SubName: Full=Signal transduction histidine kinase {ECO:0000313|EMBL:SFW72702.1};
GN   ORFNames=SAMN04489730_3492 {ECO:0000313|EMBL:SFW72702.1};
OS   Amycolatopsis australiensis.
OC   Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC   Pseudonocardiaceae; Amycolatopsis.
OX   NCBI_TaxID=546364 {ECO:0000313|EMBL:SFW72702.1, ECO:0000313|Proteomes:UP000182740};
RN   [1] {ECO:0000313|EMBL:SFW72702.1, ECO:0000313|Proteomes:UP000182740}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 44671 {ECO:0000313|EMBL:SFW72702.1,
RC   ECO:0000313|Proteomes:UP000182740};
RA   Jaros S., Januszkiewicz K., Wedrychowicz H.;
RL   Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FPJG01000006; SFW72702.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1K1RLX2; -.
DR   STRING; 546364.SAMN04489730_3492; -.
DR   Proteomes; UP000182740; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR   CDD; cd16917; HATPase_UhpB-NarQ-NarX-like; 1.
DR   Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR   InterPro; IPR003594; HATPase_C.
DR   InterPro; IPR036890; HATPase_C_sf.
DR   PANTHER; PTHR24421; NITRATE/NITRITE SENSOR PROTEIN NARX-RELATED; 1.
DR   PANTHER; PTHR24421:SF37; SIGNAL TRANSDUCTION HISTIDINE-PROTEIN KINASE_PHOSPHATASE UHPB; 1.
DR   Pfam; PF02518; HATPase_c; 1.
DR   SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
PE   4: Predicted;
KW   Kinase {ECO:0000313|EMBL:SFW72702.1}; Membrane {ECO:0000256|SAM:Phobius};
KW   Transferase {ECO:0000313|EMBL:SFW72702.1};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        42..71
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        83..105
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        136..155
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        161..181
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          298..386
FT                   /note="Histidine kinase/HSP90-like ATPase"
FT                   /evidence="ECO:0000259|Pfam:PF02518"
SQ   SEQUENCE   392 AA;  40630 MW;  68CC7D8DDE57383B CRC64;
     MRVVLLGGAG ALAGGSGRFG LSLVQGAVPR LVLVPVVFRL ALFLQAVWAA DGLAAPALGI
     AVALYVVPNL LEVAWVFRRG TGIPAVLAAD TAYTVVSSVV AAAFAADVPG LLALTWPNIM
     GTVMVWTLLR GAPAGAAAIA AAVLLRYGMA AVAGTSAPAT WILFALLAAA VTALAIVLLV
     AGSMRFALGL GEQRGRAAER ERHRRDVHDT VLQVMESLAL PAPRDAVDPV GSLDQVRRTA
     RAHALRLRLS LDGDAPAEPG GLEHRLGALA VEMTADGLRV DLVTLAKPAE VPESVVHALH
     DAAREALRNT LKHAKTTRAV VCLEEREGLV TVSVRDHGTG FDVAARPPGF GIENSIHARM
     AEVGGTARIH SAPGQGTRVV LSAPLELRFP VG
//