ID A0A1K1SEP7_9PSEU Unreviewed; 943 AA.
AC A0A1K1SEP7;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=beta-galactosidase {ECO:0000256|ARBA:ARBA00012756};
DE EC=3.2.1.23 {ECO:0000256|ARBA:ARBA00012756};
DE AltName: Full=Lactase {ECO:0000256|ARBA:ARBA00032230};
GN ORFNames=SAMN04489730_5519 {ECO:0000313|EMBL:SFW82859.1};
OS Amycolatopsis australiensis.
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Amycolatopsis.
OX NCBI_TaxID=546364 {ECO:0000313|EMBL:SFW82859.1, ECO:0000313|Proteomes:UP000182740};
RN [1] {ECO:0000313|EMBL:SFW82859.1, ECO:0000313|Proteomes:UP000182740}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 44671 {ECO:0000313|EMBL:SFW82859.1,
RC ECO:0000313|Proteomes:UP000182740};
RA Jaros S., Januszkiewicz K., Wedrychowicz H.;
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Hydrolysis of terminal non-reducing beta-D-galactose residues
CC in beta-D-galactosides.; EC=3.2.1.23;
CC Evidence={ECO:0000256|ARBA:ARBA00001412};
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 2 family.
CC {ECO:0000256|ARBA:ARBA00007401}.
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DR EMBL; FPJG01000006; SFW82859.1; -; Genomic_DNA.
DR RefSeq; WP_072478991.1; NZ_FPJG01000006.1.
DR AlphaFoldDB; A0A1K1SEP7; -.
DR STRING; 546364.SAMN04489730_5519; -.
DR OrthoDB; 9762066at2; -.
DR Proteomes; UP000182740; Unassembled WGS sequence.
DR GO; GO:0009341; C:beta-galactosidase complex; IEA:InterPro.
DR GO; GO:0004565; F:beta-galactosidase activity; IEA:UniProtKB-EC.
DR GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR GO; GO:1901575; P:organic substance catabolic process; IEA:UniProt.
DR Gene3D; 2.70.98.10; -; 1.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 2.
DR InterPro; IPR004199; B-gal_small/dom_5.
DR InterPro; IPR036156; Beta-gal/glucu_dom_sf.
DR InterPro; IPR011013; Gal_mutarotase_sf_dom.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR014718; GH-type_carb-bd.
DR InterPro; IPR006101; Glyco_hydro_2.
DR InterPro; IPR023232; Glyco_hydro_2_AS.
DR InterPro; IPR006103; Glyco_hydro_2_cat.
DR InterPro; IPR023230; Glyco_hydro_2_CS.
DR InterPro; IPR006104; Glyco_hydro_2_N.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR032312; LacZ_4.
DR PANTHER; PTHR46323; BETA-GALACTOSIDASE; 1.
DR PANTHER; PTHR46323:SF2; BETA-GALACTOSIDASE; 1.
DR Pfam; PF02929; Bgal_small_N; 1.
DR Pfam; PF02836; Glyco_hydro_2_C; 1.
DR Pfam; PF02837; Glyco_hydro_2_N; 1.
DR Pfam; PF16353; LacZ_4; 1.
DR PRINTS; PR00132; GLHYDRLASE2.
DR SMART; SM01038; Bgal_small_N; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF49303; beta-Galactosidase/glucuronidase domain; 2.
DR SUPFAM; SSF74650; Galactose mutarotase-like; 1.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
DR PROSITE; PS00719; GLYCOSYL_HYDROL_F2_1; 1.
DR PROSITE; PS00608; GLYCOSYL_HYDROL_F2_2; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801}.
FT DOMAIN 676..940
FT /note="Beta galactosidase small chain/"
FT /evidence="ECO:0000259|SMART:SM01038"
SQ SEQUENCE 943 AA; 103350 MW; 53B232C6A5FE0F94 CRC64;
MSYVEDPGPG YGALPPRAAF TSDAPSLSLN GTWRFRLSPS VAAAPPGVEG DEFDDSAWDE
LPVPSLWQLH GHGRPAYTNV HYPFPVDPPH VPSENPTGDH RLRFDLPADW PAGPAVLRFD
GIDSCGRIWL NGVELGVTKG SRLPSEFEVG PLLRPRGNVL AVRVHQWSAG SYLEDQDMWW
LSGIFRSVTL LARPAGGIGD HWIRADYDHE SGLGTVRVET GPDVVLDIPE LGVSGHPAGE
PLALPVEPWS AETPRLYAGT LSTAAERVPV RIGFRTVTIE DGQLEVNGRR LLLRGVNRHE
HDPRTGRVVS PETALADVLL MKRHHVNAVR TSHYPPDPAF LELCDEYGLW VIDECDLETH
GFGPLGWDRN PSGEPMWAEA CLDRMRRTVE RDKNRPSVIL WSLGNESHTG ENLARMAAWV
RHRDPTRPVH YEGDHDCSYV DVHSRMYATP SEVERIGQRD DANARRRELP FLLCEYGHAM
GNGPGGLLEY RELFERYPNC QGGFVWEWID HGLVTADHFA YGGDFGEPIH DGNFVIDGLV
FPDRTPSPGL AEYAKIIEPV RVGPDPAGIR VSNHYDFRST AHLAFTWVLE DEGTAVARGV
LDVPVVHSGQ SVVVPRPDLP VTRGESWLTV SAVLADATAW APAGHVAGWG QLLVSPAPPR
PSRPARGPVF RTAGRLILGD GEFDPATGAM TTFGGHAVRG PRLDVWRATT DNDRGASAGR
PDASLWREAG LHRMQHRVIG VDADGDELVV RTRVAPPAQA FGFFADYTWT AFDDGLRLRV
AVTPDGPVPE TIPRLGLTMA VPGTFGSAEW FGGGPGEAYP DSRQAARIGR FSSSVDGLQT
PYVYPQENGN RIDVRWARLT DPDGRGIRID GDPRFAFTAR RWTAAELEAA RHTSDLVAGP
WVHVTLDTAQ HGLGSASCGP GVLPPYRLVP QKTEFSLLFS TSR
//
