ID A0A1K1W6U4_9GAMM Unreviewed; 398 AA.
AC A0A1K1W6U4;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=SAM-dependent methyltransferase {ECO:0000313|EMBL:SFX33090.1};
GN ORFNames=SAMN02745752_01318 {ECO:0000313|EMBL:SFX33090.1};
OS Marinospirillum alkaliphilum DSM 21637.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Oceanospirillales;
OC Oceanospirillaceae; Marinospirillum.
OX NCBI_TaxID=1122209 {ECO:0000313|EMBL:SFX33090.1, ECO:0000313|Proteomes:UP000182350};
RN [1] {ECO:0000313|EMBL:SFX33090.1, ECO:0000313|Proteomes:UP000182350}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 21637 {ECO:0000313|EMBL:SFX33090.1,
RC ECO:0000313|Proteomes:UP000182350};
RA Jaros S., Januszkiewicz K., Wedrychowicz H.;
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the methyltransferase superfamily. RlmI family.
CC {ECO:0000256|ARBA:ARBA00038091}.
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DR EMBL; FPJW01000003; SFX33090.1; -; Genomic_DNA.
DR RefSeq; WP_072325548.1; NZ_FPJW01000003.1.
DR AlphaFoldDB; A0A1K1W6U4; -.
DR STRING; 1122209.SAMN02745752_01318; -.
DR OrthoDB; 9805492at2; -.
DR Proteomes; UP000182350; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR CDD; cd02440; AdoMet_MTases; 1.
DR CDD; cd21153; PUA_RlmI; 1.
DR CDD; cd11572; RlmI_M_like; 1.
DR Gene3D; 2.30.130.10; PUA domain; 1.
DR Gene3D; 3.30.750.80; RNA methyltransferase domain (HRMD) like; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR015947; PUA-like_sf.
DR InterPro; IPR036974; PUA_sf.
DR InterPro; IPR041532; RlmI-like_PUA.
DR InterPro; IPR019614; SAM-dep_methyl-trfase.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR42873:SF1; METHYLTRANS_SAM DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR42873; RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE; 1.
DR Pfam; PF10672; Methyltrans_SAM; 1.
DR Pfam; PF17785; PUA_3; 1.
DR SUPFAM; SSF88697; PUA domain-like; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS50890; PUA; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW ECO:0000313|EMBL:SFX33090.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000182350};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:SFX33090.1}.
FT DOMAIN 6..71
FT /note="RlmI-like PUA"
FT /evidence="ECO:0000259|Pfam:PF17785"
FT DOMAIN 115..307
FT /note="S-adenosylmethionine-dependent methyltransferase"
FT /evidence="ECO:0000259|Pfam:PF10672"
SQ SEQUENCE 398 AA; 44180 MW; B9F9B8E40C1AB9E2 CRC64;
MTLERLRLKK NADRRLKAGH LWIYSNEVDT AVTPLKGLQP GEQRLVESAS GQPLGVAYVH
PNNLICARLI SEKPDQSLDL ALLKTRIRQA LTLRETFYQK PFYRLVYGES DLLPGLIVDR
FDAVLVVQLN TAGMDALRDE VLLALREVIQ PQAIVWRNDA GARQLEGLDA EVGLAWGELP
DQVLAEENGC VFDVPVLDGQ KTGWFYDHQP NRAALLPLVK GKRVLDVFSY RGAWGMPLAK
AGAREVVFLD ASAAALEGVQ LNAALNGVAD RVSTLCADAF EGLQQLQQAG EQFDLVILDP
PAFIKRKKDQ GPGEHAYQRL NREAMKLLPP EDGLLLSGSC SMHLAEERLQ DLVRIAARRQ
QQMAQLVWRG GQGADHPVHP AIPETRYLKA LLFRLVSQ
//
