ID   A0A1K2FJ51_9ACTN        Unreviewed;       432 AA.
AC   A0A1K2FJ51;
DT   15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT   15-FEB-2017, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   RecName: Full=HpcH/HpaI aldolase/citrate lyase domain-containing protein {ECO:0000259|Pfam:PF03328};
GN   ORFNames=STEPF1_00940 {ECO:0000313|EMBL:SFY47729.1};
OS   Streptomyces sp. F-1.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=463642 {ECO:0000313|EMBL:SFY47729.1, ECO:0000313|Proteomes:UP000095403};
RN   [1] {ECO:0000313|EMBL:SFY47729.1, ECO:0000313|Proteomes:UP000095403}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Streptomyces sp. F1 {ECO:0000313|EMBL:SFY47729.1};
RA   Jaros S., Januszkiewicz K., Wedrychowicz H.;
RL   Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC         Evidence={ECO:0000256|ARBA:ARBA00001946};
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DR   EMBL; FKJI03000002; SFY47729.1; -; Genomic_DNA.
DR   RefSeq; WP_070026493.1; NZ_FKJI03000002.1.
DR   AlphaFoldDB; A0A1K2FJ51; -.
DR   OrthoDB; 9808769at2; -.
DR   Proteomes; UP000095403; Unassembled WGS sequence.
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   Gene3D; 3.20.20.60; Phosphoenolpyruvate-binding domains; 1.
DR   InterPro; IPR005000; Aldolase/citrate-lyase_domain.
DR   InterPro; IPR015813; Pyrv/PenolPyrv_Kinase-like_dom.
DR   InterPro; IPR040442; Pyrv_Kinase-like_dom_sf.
DR   PANTHER; PTHR32308:SF10; CITRATE LYASE SUBUNIT BETA; 1.
DR   PANTHER; PTHR32308; LYASE BETA SUBUNIT, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G13030)-RELATED; 1.
DR   Pfam; PF03328; HpcH_HpaI; 1.
DR   SUPFAM; SSF51621; Phosphoenolpyruvate/pyruvate domain; 1.
PE   4: Predicted;
KW   Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000095403}.
FT   DOMAIN          187..294
FT                   /note="HpcH/HpaI aldolase/citrate lyase"
FT                   /evidence="ECO:0000259|Pfam:PF03328"
SQ   SEQUENCE   432 AA;  45769 MW;  8F11A512DB87FB7F CRC64;
     MGQQEKVATS LTGAVGEEIS ALLAPVDAEL ARRYPGDPGT RQPVHTVYVP GDAFAADTVR
     SWGDRALAAL DEHAPDAASF AAVLGLADDL AEPVYSRVRA KLEREPIEDL RVDFEDGYGP
     RPDAEEDAAA ARAARLIAEA AGSGTAAPYT GIRMKCMEAA VRERGIRTLD VFLTGLMAAG
     GLPDGLVLTL PKVTYPEQVS AFVRILEAFE KTHGLDAGRL GFEIQIETSQ AILATDGTAT
     VARMIQAAEG RATGLHYGTF DYSACLGVSA AYQASDHPAA DHAKAVMQVA AAGTGVRVSD
     GSTNVLPVGP TDRVHDAWRL HYGLTRRALA RAYYQGWDMH PGHIPTRYAA VFAFYREGFE
     QAADRLARYA SRAGGDVMDE PATAKALGGY LLRGLDCGAL DPAEVQERTG LTRAALEGFA
     APRRGDLTAS AQ
//