ID A0A1K2FNJ3_9ACTN Unreviewed; 681 AA.
AC A0A1K2FNJ3;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Efem/EfeO family lipoprotein {ECO:0000313|EMBL:SFY48599.1};
GN ORFNames=STEPF1_01824 {ECO:0000313|EMBL:SFY48599.1};
OS Streptomyces sp. F-1.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=463642 {ECO:0000313|EMBL:SFY48599.1, ECO:0000313|Proteomes:UP000095403};
RN [1] {ECO:0000313|EMBL:SFY48599.1, ECO:0000313|Proteomes:UP000095403}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Streptomyces sp. F1 {ECO:0000313|EMBL:SFY48599.1};
RA Jaros S., Januszkiewicz K., Wedrychowicz H.;
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the EfeM/EfeO family.
CC {ECO:0000256|ARBA:ARBA00005989}.
CC -!- SIMILARITY: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC
CC 9.A.10.1) family. {ECO:0000256|ARBA:ARBA00008333}.
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DR EMBL; FKJI03000003; SFY48599.1; -; Genomic_DNA.
DR RefSeq; WP_070023375.1; NZ_FKJI03000003.1.
DR AlphaFoldDB; A0A1K2FNJ3; -.
DR OrthoDB; 7260758at2; -.
DR Proteomes; UP000095403; Unassembled WGS sequence.
DR GO; GO:0033573; C:high-affinity iron permease complex; IEA:InterPro.
DR GO; GO:0005381; F:iron ion transmembrane transporter activity; IEA:InterPro.
DR CDD; cd14656; Imelysin-like_EfeO; 1.
DR Gene3D; 1.20.1420.20; M75 peptidase, HXXE motif; 1.
DR InterPro; IPR004923; FTR1/Fip1/EfeU.
DR InterPro; IPR018976; Imelysin-like.
DR InterPro; IPR034981; Imelysin-like_EfeO/Algp7.
DR InterPro; IPR038352; Imelysin_sf.
DR NCBIfam; NF041756; EfeU; 1.
DR PANTHER; PTHR31632; IRON TRANSPORTER FTH1; 1.
DR PANTHER; PTHR31632:SF2; PLASMA MEMBRANE IRON PERMEASE; 1.
DR Pfam; PF03239; FTR1; 1.
DR Pfam; PF09375; Peptidase_M75; 1.
PE 3: Inferred from homology;
KW Lipoprotein {ECO:0000313|EMBL:SFY48599.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000095403};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..30
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 42..62
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 74..93
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 109..129
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 149..170
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 182..202
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 247..265
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 301..322
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 439..668
FT /note="Imelysin-like"
FT /evidence="ECO:0000259|Pfam:PF09375"
FT REGION 272..296
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 681 AA; 71794 MW; 9A36E6084C34192F CRC64;
MWDDAFPSFL IGLREGLEAG LIVSILVATL VRAEARSRLP QVWTGVLAAM AVAMSFGAVL
TFTAASMPQT AQEAFGGTLS VIAVAFVTAM VFWMRRSARN LSSELKQKVT GALAMGSGML
VLTSFLAVGR EGLETALFLW TTAQAAGESA GPLAGAAIGL VLAAGLCWGL YRRVLKINLT
KFFTATGVVL VVIAAGVLGY GLRDLQEGGV LPGRTAYAVD LAGSIDAGSW YSTLVQGVFN
LMPTMTWLQV VAYVGYLVVV MTLFVRGVRA TAPKPKPEPA ERPAAEAPAG PRSRTGRRPA
WVVPVAVVAV PAVIAALVVA LGRPKPAGDQ TVAVSETDCG KGFTAPTPGR QTFRMHNTGR
QASEVYLVDP STNAVYGEIE GLAPGTTRDL VATVAGGTYA WRCVPASGKA VTSKPVTVRG
GGAAKPVTPV SEQDLAGPLK AYKAYVGHGL DTLVGQTGTL RRDIEGGHLD KARTDWLTAH
RTYASLGAAY GTFEDFDKKI DGRADGLPGG EHDKDFTGFL RLEYGLWHGQ SAKELTGPAR
QLDTDAAGLR KAFPSQDFDP GDLPLRAHEI LENTLQFELT GDTDEGSGTN LATADANLTG
TRELLTVLEP LLTSRSPRLL PTVDADIDRV HKLLDAAHDG GHWTPVEKLP AAGRQRLDGA
TGQLLEDLAP VPDLLEIRKS A
//
