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Database: UniProt
Entry: A0A1K2FQS4_9ACTN
LinkDB: A0A1K2FQS4_9ACTN
Original site: A0A1K2FQS4_9ACTN 
ID   A0A1K2FQS4_9ACTN        Unreviewed;       601 AA.
AC   A0A1K2FQS4;
DT   15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT   15-FEB-2017, sequence version 1.
DT   13-FEB-2019, entry version 12.
DE   SubName: Full=3-hydroxybutyryl-CoA dehydrogenase {ECO:0000313|EMBL:SFY49848.1};
DE            EC=1.1.1.157 {ECO:0000313|EMBL:SFY49848.1};
GN   Name=hbd_1 {ECO:0000313|EMBL:SFY49848.1};
GN   ORFNames=STEPF1_03088 {ECO:0000313|EMBL:SFY49848.1};
OS   Streptomyces sp. F-1.
OC   Bacteria; Actinobacteria; Streptomycetales; Streptomycetaceae;
OC   Streptomyces.
OX   NCBI_TaxID=463642 {ECO:0000313|EMBL:SFY49848.1, ECO:0000313|Proteomes:UP000095403};
RN   [1] {ECO:0000313|EMBL:SFY49848.1, ECO:0000313|Proteomes:UP000095403}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Streptomyces sp. F1 {ECO:0000313|EMBL:SFY49848.1};
RA   Jaros S., Januszkiewicz K., Wedrychowicz H.;
RL   Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FKJI03000006; SFY49848.1; -; Genomic_DNA.
DR   RefSeq; WP_070022776.1; NZ_FKJI03000006.1.
DR   BioCyc; GCF_900079405:G1FMJ-2289-MONOMER; -.
DR   Proteomes; UP000095403; Unassembled WGS sequence.
DR   GO; GO:0003857; F:3-hydroxyacyl-CoA dehydrogenase activity; IEA:InterPro.
DR   GO; GO:0008691; F:3-hydroxybutyryl-CoA dehydrogenase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006631; P:fatty acid metabolic process; IEA:InterPro.
DR   Gene3D; 1.10.1040.10; -; 1.
DR   InterPro; IPR006176; 3-OHacyl-CoA_DH_NAD-bd.
DR   InterPro; IPR006108; 3HC_DH_C.
DR   InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR   InterPro; IPR013328; 6PGD_dom2.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   Pfam; PF00725; 3HCDH; 2.
DR   Pfam; PF02737; 3HCDH_N; 2.
DR   SUPFAM; SSF48179; SSF48179; 2.
DR   SUPFAM; SSF51735; SSF51735; 2.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000095403};
KW   Oxidoreductase {ECO:0000313|EMBL:SFY49848.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000095403}.
FT   DOMAIN       15    193       3HCDH_N. {ECO:0000259|Pfam:PF02737}.
FT   DOMAIN      196    292       3HCDH. {ECO:0000259|Pfam:PF00725}.
FT   DOMAIN      322    499       3HCDH_N. {ECO:0000259|Pfam:PF02737}.
FT   DOMAIN      502    598       3HCDH. {ECO:0000259|Pfam:PF00725}.
SQ   SEQUENCE   601 AA;  63135 MW;  E05E57CD69C4A62B CRC64;
     MATPLSHTPP SALTKVAVVG LGTMGTGITE VLVKAGREVV GIDVGEAQAA RALAALEAST
     ARAVERGRLT GAERADALAR VRVTTDLTAA ADADLVIEVA PESYEIKHQI FRELDGIVRP
     ETILATGTNA LSVTRLAADS ARPERVLGLH FFNPAPAMKL VEIVSSVLTA PQVVAAVTDL
     ALELGKEPVA VGDRPGFVAD GLLFGYLNQA AAMYEARYAS REDIDAAMRL GCGLPMGPLA
     LLDLIGVDTA RTVLEAMYAE SHDRLHAPAP ILKQLSEAGL TGRKSGRGFY TYEAPGSATV
     VPDALTPAAG GARAEGREVR SVGVAGSGTM ASGIAEVFAK AGYGVVLAAR SEEKAQAAKA
     RIGTSLARSV DKGRLTAEAA AETLDRITPA GSYDAFADVD LAVEAVAEDL EVKRQLFQTL
     DKVCKPGAVL ATTTSSLPVV ACARATSRPQ DVIGMHFFNP APAMKLVEVV RTVLTADDVH
     ATVREVCAKI RKHPVDCGDR AGFIVNALLF PYLNNAIKMV QEHYASLDDI DAAMRLGGGY
     PMGPFELLDV VGLDVSLAIE KVLHREFRDP GLAPAPLLEH LVAAGCLGRK TGRGFREYAR
     R
//
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