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Database: UniProt
Entry: A0A1K2FZN6_9ACTN
LinkDB: A0A1K2FZN6_9ACTN
Original site: A0A1K2FZN6_9ACTN 
ID   A0A1K2FZN6_9ACTN        Unreviewed;       234 AA.
AC   A0A1K2FZN6;
DT   15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT   15-FEB-2017, sequence version 1.
DT   03-JUL-2019, entry version 16.
DE   RecName: Full=Urease subunit gamma/beta {ECO:0000256|HAMAP-Rule:MF_01955};
DE            EC=3.5.1.5 {ECO:0000256|HAMAP-Rule:MF_01955};
DE   AltName: Full=Urea amidohydrolase subunit gamma/beta {ECO:0000256|HAMAP-Rule:MF_01955};
GN   Name=ureA_3 {ECO:0000313|EMBL:SFY53032.1};
GN   Synonyms=ureAB {ECO:0000256|HAMAP-Rule:MF_01955};
GN   ORFNames=STEPF1_06307 {ECO:0000313|EMBL:SFY53032.1};
OS   Streptomyces sp. F-1.
OC   Bacteria; Actinobacteria; Streptomycetales; Streptomycetaceae;
OC   Streptomyces.
OX   NCBI_TaxID=463642 {ECO:0000313|EMBL:SFY53032.1, ECO:0000313|Proteomes:UP000095403};
RN   [1] {ECO:0000313|EMBL:SFY53032.1, ECO:0000313|Proteomes:UP000095403}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Streptomyces sp. F1 {ECO:0000313|EMBL:SFY53032.1};
RA   Jaros S., Januszkiewicz K., Wedrychowicz H.;
RL   Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=2 H(+) + H2O + urea = CO2 + 2 NH4(+);
CC         Xref=Rhea:RHEA:20557, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:16199, ChEBI:CHEBI:16526, ChEBI:CHEBI:28938;
CC         EC=3.5.1.5; Evidence={ECO:0000256|HAMAP-Rule:MF_01955,
CC         ECO:0000256|SAAS:SAAS01115730};
CC   -!- PATHWAY: Nitrogen metabolism; urea degradation; CO(2) and NH(3)
CC       from urea (urease route): step 1/1. {ECO:0000256|HAMAP-
CC       Rule:MF_01955, ECO:0000256|SAAS:SAAS00108095}.
CC   -!- SUBUNIT: Heterohexamer of 3 UreC (alpha) and 3 UreAB (gamma/beta)
CC       subunits. {ECO:0000256|HAMAP-Rule:MF_01955}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_01955}.
CC   -!- SIMILARITY: In the C-terminal section; belongs to the urease beta
CC       subunit family. {ECO:0000256|HAMAP-Rule:MF_01955}.
CC   -!- SIMILARITY: In the N-terminal section; belongs to the urease gamma
CC       subunit family. {ECO:0000256|HAMAP-Rule:MF_01955}.
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DR   EMBL; FKJI03000033; SFY53032.1; -; Genomic_DNA.
DR   RefSeq; WP_070023042.1; NZ_FKJI03000033.1.
DR   BioCyc; GCF_900079405:G1FMJ-6942-MONOMER; -.
DR   UniPathway; UPA00258; UER00370.
DR   Proteomes; UP000095403; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0016151; F:nickel cation binding; IEA:InterPro.
DR   GO; GO:0009039; F:urease activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0043419; P:urea catabolic process; IEA:UniProtKB-UniPathway.
DR   CDD; cd00407; Urease_beta; 1.
DR   CDD; cd00390; Urease_gamma; 1.
DR   Gene3D; 2.10.150.10; -; 1.
DR   Gene3D; 3.30.280.10; -; 1.
DR   HAMAP; MF_01955; Urease_beta_gamma; 1.
DR   InterPro; IPR002019; Urease_beta.
DR   InterPro; IPR036461; Urease_betasu_sf.
DR   InterPro; IPR008223; Urease_gamma-beta_su.
DR   InterPro; IPR002026; Urease_gamma/gamma-beta_su.
DR   InterPro; IPR036463; Urease_gamma_sf.
DR   Pfam; PF00699; Urease_beta; 1.
DR   Pfam; PF00547; Urease_gamma; 1.
DR   PIRSF; PIRSF001225; Urease_gammabeta; 1.
DR   SUPFAM; SSF51278; SSF51278; 1.
DR   SUPFAM; SSF54111; SSF54111; 1.
DR   TIGRFAMs; TIGR00192; urease_beta; 1.
DR   TIGRFAMs; TIGR00193; urease_gam; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000095403};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_01955};
KW   Hydrolase {ECO:0000256|HAMAP-Rule:MF_01955,
KW   ECO:0000256|SAAS:SAAS00108092, ECO:0000313|EMBL:SFY53032.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000095403}.
FT   REGION        1    101       Urease gamma. {ECO:0000256|HAMAP-Rule:
FT                                MF_01955}.
FT   REGION      102    234       Urease beta. {ECO:0000256|HAMAP-Rule:
FT                                MF_01955}.
SQ   SEQUENCE   234 AA;  24366 MW;  5356618F71E364AC CRC64;
     MRLTPTERDR LLLFGAAELA RARRARGLRL NVPEATALIA DTVCEAARDG RRLAEAIEAA
     RAVLGPEDVL PGVADVVTEV MVEAVFDDGS RLAVVCDPIG GGLGDDAPGA LLPGPAHADP
     EPVVRLTVTN TATVPVSVTS HFHFFEANPR LDFDRAAAYG MRLAVPAGSS VRFGPGESEE
     VGLVPIGGER IAIGFAGLVD GPLDAPGARQ EALRRAAACG YLGARSAEEK GQDR
//
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