ID A0A1L0BD00_9ASCO Unreviewed; 358 AA.
AC A0A1L0BD00;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 24-JAN-2024, entry version 29.
DE RecName: Full=histone acetyltransferase {ECO:0000256|ARBA:ARBA00013184};
DE EC=2.3.1.48 {ECO:0000256|ARBA:ARBA00013184};
GN ORFNames=SAMEA4029010_CIC11G00000001867 {ECO:0000313|EMBL:SGZ49503.1};
OS [Candida] intermedia.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Metschnikowiaceae; Metschnikowiaceae incertae sedis;
OC Candida/Metschnikowiaceae.
OX NCBI_TaxID=45354 {ECO:0000313|EMBL:SGZ49503.1, ECO:0000313|Proteomes:UP000182334};
RN [1] {ECO:0000313|EMBL:SGZ49503.1, ECO:0000313|Proteomes:UP000182334}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 141442 {ECO:0000313|EMBL:SGZ49503.1,
RC ECO:0000313|Proteomes:UP000182334};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the MYST (SAS/MOZ) family.
CC {ECO:0000256|ARBA:ARBA00010107}.
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DR EMBL; LT635757; SGZ49503.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1L0BD00; -.
DR STRING; 45354.A0A1L0BD00; -.
DR OrthoDB; 118560at2759; -.
DR Proteomes; UP000182334; Chromosome ii.
DR GO; GO:0004402; F:histone acetyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR Gene3D; 3.40.630.30; -; 1.
DR Gene3D; 3.30.60.60; N-acetyl transferase-like; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR016181; Acyl_CoA_acyltransferase.
DR InterPro; IPR002717; HAT_MYST-type.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR10615; HISTONE ACETYLTRANSFERASE; 1.
DR PANTHER; PTHR10615:SF180; HISTONE ACETYLTRANSFERASE SAS2; 1.
DR Pfam; PF01853; MOZ_SAS; 1.
DR SUPFAM; SSF55729; Acyl-CoA N-acyltransferases (Nat); 1.
DR PROSITE; PS51726; MYST_HAT; 1.
PE 3: Inferred from homology;
KW Acetylation {ECO:0000256|ARBA:ARBA00022990};
KW Chromatin regulator {ECO:0000256|ARBA:ARBA00022853};
KW Reference proteome {ECO:0000313|Proteomes:UP000182334};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 31..338
FT /note="MYST-type HAT"
FT /evidence="ECO:0000259|PROSITE:PS51726"
FT REGION 1..25
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 254
FT /note="Proton donor/acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR602717-51"
SQ SEQUENCE 358 AA; 40947 MW; 3830FC34A5BAE0D3 CRC64;
MDPISPQGVT LPLPKPHSRR KTPRDTEYGV LESRNINRVS FGDYEFNTWY GNSAYFLANG
DLELGIDTLA KNIGAKRKFS AAALEGFWLD RLHVCEFCFK YTDNENKMVQ HRSVCQLAHP
FPPLGKLLYA DMKAPYLVKK VRGFRHELFC QNLALFGKLF LDDKSVYYNV KAFDFYILYG
YDVHDDEIAG SILRKRLKPM GFFSKEVNSW EADNNLACIC IFPPYQRLGL GSLLIEFLYA
LAGATPGQTW LGPEFPLSPY GKVAYLGYWS KRLAFVLLND FRGRDSVTLA ELASRTGFRK
DDILFTLEYM EVLQESKKES VEDDSVSLIL LNLHLWCSKH HVSESVMASM MNTLCLLI
//
