ID A0A1L0GLD5_9ASCO Unreviewed; 971 AA.
AC A0A1L0GLD5;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=CIC11C00000001030 {ECO:0000313|EMBL:SGZ56989.1};
GN ORFNames=SAMEA4029010_CIC11G00000001030 {ECO:0000313|EMBL:SGZ56989.1};
OS [Candida] intermedia.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Metschnikowiaceae; Metschnikowiaceae incertae sedis;
OC Candida/Metschnikowiaceae.
OX NCBI_TaxID=45354 {ECO:0000313|EMBL:SGZ56989.1, ECO:0000313|Proteomes:UP000182334};
RN [1] {ECO:0000313|EMBL:SGZ56989.1, ECO:0000313|Proteomes:UP000182334}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 141442 {ECO:0000313|EMBL:SGZ56989.1,
RC ECO:0000313|Proteomes:UP000182334};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; LT635761; SGZ56989.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1L0GLD5; -.
DR STRING; 45354.A0A1L0GLD5; -.
DR OrthoDB; 25690at2759; -.
DR Proteomes; UP000182334; Chromosome vi.
DR GO; GO:0005933; C:cellular bud; IEA:UniProt.
DR GO; GO:0005096; F:GTPase activator activity; IEA:UniProt.
DR GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd06093; PX_domain; 1.
DR Gene3D; 3.30.1520.10; Phox-like domain; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR InterPro; IPR001683; PX_dom.
DR InterPro; IPR036871; PX_dom_sf.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR InterPro; IPR000198; RhoGAP_dom.
DR PANTHER; PTHR23176:SF129; RHO GTPASE ACTIVATING PROTEIN AT 16F, ISOFORM E-RELATED; 1.
DR PANTHER; PTHR23176; RHO/RAC/CDC GTPASE-ACTIVATING PROTEIN; 1.
DR Pfam; PF00169; PH; 1.
DR Pfam; PF00787; PX; 1.
DR Pfam; PF00620; RhoGAP; 1.
DR SMART; SM00233; PH; 1.
DR SMART; SM00324; RhoGAP; 1.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF64268; PX domain; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
DR PROSITE; PS50238; RHOGAP; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000182334}.
FT DOMAIN 526..637
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT DOMAIN 762..971
FT /note="Rho-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50238"
FT REGION 92..131
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 164..184
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 319..379
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 715..734
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 93..124
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 164..178
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 971 AA; 108711 MW; 4EC8967E09A96A28 CRC64;
MSDSGSDSKD DGLHHQMIED QDEMVNRMLL PSHPNFDRRE HTSEEFIELL LSEINDLKIA
LKSKDIMITN FQAQLEHFNV DSTGVLIANT HSHLRTPDED VPQRSARRKL SQKGPEEAVS
SAESDSRRES IASITSNGPI AAIDGMPLSS NFRSELSAAL GITTSNELSP QTSRHDLNVP
GLDETPRILN SDDVVDLTVL NTNIQGVEFD QNASNKDVEG TANELVSSRK ASNPSVNSYK
SRIKLPPTLK QPDLTCNAPS TPLINQESHP MNNQISFKNK ADLAAEAAKN QEPRLPLTPD
GLSSNGKFFA RTEASGQLSE DSHSYFGSPF TNSPPNSSMT PTTNSNMEIS KTPNTHTFAS
TDSFHSYQRP SSQTPGSSFH VLSTPKLEDE SVELFIKPEE FQSIRIHVVS TISANTKKAD
DPNCTLSIND KETSKEMWRI RKTLSQLVAF DAEIRPVVEF FGLPPLPEKS LFSSTTPLKV
DSRRISLQNY FNTLFVMPHV PRLVLFRICR FLSLDFVNLL DDFRTGAKKE GFLIRRYKGL
GLGTAWKVRW CQVDGPELEI YDSPGGNLLE LIKLIGSQIG RQSSDTVAEQ RGYRHAFLIL
ENAKISKLSA SSSKHFFCSE SDSERDEWVA AMVEYTENDP LASNDDQNSL QELDSPHVML
NEDFDQSNRY LSGTSSNYAH LSFEADSSFV TILDESQREA KRATRKKSRF PFRNRVSTHS
ETHVNQQENQ IVSSPQRSEL PMQTYLDQMK LSDEPARVIF GRDIEEAFRL SNHSYNGRQV
PSICYRCLDF LSKTGAVYEE GIFRLSGSAS SIRQLKENFN SVHDVDLFES PLRPDMHTVA
GLLKTYLREL PNPVFGRKAY SELQSLVSQT GGSPNSSTVY MMRDFLRDSG LVSKVNFDFC
VTIFGYLRSV ITKSSTNKMS LRNVCIVFVP TLNISIDILS VCLTDFDCIF GNGDPIPDEK
RLVLDLQIPT F
//
