ID A0A1L1RUU9_CHICK Unreviewed; 172 AA.
AC A0A1L1RUU9; A0A1D5PNS5;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 2.
DT 27-MAR-2024, entry version 36.
DE SubName: Full=Myosin light chain 12B {ECO:0000313|Ensembl:ENSGALP00010003167.1};
GN Name=MYL12B {ECO:0000313|Ensembl:ENSGALP00010003167.1};
OS Gallus gallus (Chicken).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC Phasianinae; Gallus.
OX NCBI_TaxID=9031 {ECO:0000313|Ensembl:ENSGALP00010003167.1, ECO:0000313|Proteomes:UP000000539};
RN [1] {ECO:0000313|Ensembl:ENSGALP00010003167.1}
RP IDENTIFICATION.
RC STRAIN=broiler {ECO:0000313|Ensembl:ENSGALP00010003167.1};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBUNIT: Myosin is a hexamer of 2 heavy chains and 4 light chains.
CC {ECO:0000256|ARBA:ARBA00011445}.
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DR RefSeq; XP_001233329.2; XM_001233328.4.
DR AlphaFoldDB; A0A1L1RUU9; -.
DR SMR; A0A1L1RUU9; -.
DR STRING; 9031.ENSGALP00000059245; -.
DR PaxDb; 9031-ENSGALP00000023926; -.
DR Ensembl; ENSGALT00010005328.1; ENSGALP00010003167.1; ENSGALG00010002352.1.
DR GeneID; 770011; -.
DR KEGG; gga:770011; -.
DR CTD; 103910; -.
DR VEuPathDB; HostDB:geneid_770011; -.
DR GeneTree; ENSGT00940000153607; -.
DR InParanoid; A0A1L1RUU9; -.
DR OMA; FECFDEN; -.
DR OrthoDB; 312751at2759; -.
DR Reactome; R-GGA-445355; Smooth Muscle Contraction.
DR Reactome; R-GGA-5627123; RHO GTPases activate PAKs.
DR Proteomes; UP000000539; Chromosome 2.
DR Bgee; ENSGALG00000038635; Expressed in ovary and 14 other cell types or tissues.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0030016; C:myofibril; IBA:GO_Central.
DR GO; GO:0001725; C:stress fiber; IBA:GO_Central.
DR GO; GO:0005509; F:calcium ion binding; IBA:GO_Central.
DR CDD; cd00051; EFh; 1.
DR Gene3D; 1.10.238.10; EF-hand; 2.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR InterPro; IPR002048; EF_hand_dom.
DR PANTHER; PTHR23049:SF71; MYOSIN REGULATORY LIGHT CHAIN 12B; 1.
DR PANTHER; PTHR23049; MYOSIN REGULATORY LIGHT CHAIN 2; 1.
DR Pfam; PF13499; EF-hand_7; 2.
DR SMART; SM00054; EFh; 2.
DR SUPFAM; SSF47473; EF-hand; 1.
DR PROSITE; PS00018; EF_HAND_1; 1.
DR PROSITE; PS50222; EF_HAND_2; 2.
PE 4: Predicted;
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000000539};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 29..64
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 98..133
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
SQ SEQUENCE 172 AA; 19883 MW; FFBFD24124A2C740 CRC64;
MSSKKAKTKT TKKRPQRATS NVFAMFDQSQ IQEFKEAFNM IDQNRDGFID KEDLHDMLAS
LGKNPTDEYL DAMMNEAPGP INFTMFLTMF GEKLNGTDPE DVIRNAFACF DEEATGFIQE
DYLRELLTTM GDRFTDEEVD ELYREAPIDK KGNFNYIEFT RILKHGAKDK DD
//
