ID A0A1L1SRA5_MOUSE Unreviewed; 180 AA.
AC A0A1L1SRA5;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE RecName: Full=High mobility group protein 20A {ECO:0000256|ARBA:ARBA00039787};
DE AltName: Full=HMG box-containing protein 20A {ECO:0000256|ARBA:ARBA00043040};
GN Name=Hmg20a {ECO:0000313|Ensembl:ENSMUSP00000149375.2,
GN ECO:0000313|MGI:MGI:1914117};
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000149375.2, ECO:0000313|Proteomes:UP000000589};
RN [1] {ECO:0000313|Ensembl:ENSMUSP00000149375.2, ECO:0000313|Proteomes:UP000000589}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000149375.2,
RC ECO:0000313|Proteomes:UP000000589};
RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA Eichler E.E., Ponting C.P.;
RT "Lineage-specific biology revealed by a finished genome assembly of the
RT mouse.";
RL PLoS Biol. 7:E1000112-E1000112(2009).
RN [2] {ECO:0007829|PubMed:21183079}
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=21183079; DOI=10.1016/j.cell.2010.12.001;
RA Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R.,
RA Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.;
RT "A tissue-specific atlas of mouse protein phosphorylation and expression.";
RL Cell 143:1174-1189(2010).
RN [3] {ECO:0000313|Ensembl:ENSMUSP00000149375.2}
RP IDENTIFICATION.
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000149375.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; A0A1L1SRA5; -.
DR SMR; A0A1L1SRA5; -.
DR jPOST; A0A1L1SRA5; -.
DR ProteomicsDB; 352984; -.
DR Antibodypedia; 1449; 372 antibodies from 33 providers.
DR Ensembl; ENSMUST00000214771.2; ENSMUSP00000149375.2; ENSMUSG00000032329.5.
DR AGR; MGI:1914117; -.
DR MGI; MGI:1914117; Hmg20a.
DR VEuPathDB; HostDB:ENSMUSG00000032329; -.
DR GeneTree; ENSGT00940000158464; -.
DR ChiTaRS; Hmg20a; mouse.
DR Proteomes; UP000000589; Chromosome 9.
DR Bgee; ENSMUSG00000032329; Expressed in humerus cartilage element and 270 other cell types or tissues.
DR ExpressionAtlas; A0A1L1SRA5; baseline and differential.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-UniRule.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR Gene3D; 1.10.30.10; High mobility group box domain; 1.
DR InterPro; IPR009071; HMG_box_dom.
DR InterPro; IPR036910; HMG_box_dom_sf.
DR PANTHER; PTHR46040; HIGH MOBILITY GROUP PROTEIN 2; 1.
DR PANTHER; PTHR46040:SF1; HIGH MOBILITY GROUP PROTEIN 20A-RELATED; 1.
DR Pfam; PF00505; HMG_box; 1.
DR SMART; SM00398; HMG; 1.
DR SUPFAM; SSF47095; HMG-box; 1.
DR PROSITE; PS50118; HMG_BOX_2; 1.
PE 1: Evidence at protein level;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00267};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00267};
KW Proteomics identification {ECO:0007829|EPD:A0A1L1SRA5,
KW ECO:0007829|MaxQB:A0A1L1SRA5};
KW Reference proteome {ECO:0000313|Proteomes:UP000000589}.
FT DOMAIN 102..149
FT /note="HMG box"
FT /evidence="ECO:0000259|PROSITE:PS50118"
FT DNA_BIND 102..149
FT /note="HMG box"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00267"
FT REGION 1..108
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 38..69
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 70..84
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 180 AA; 19844 MW; E176D4DD46270F24 CRC64;
MESLMASSTL PPLFADEDGS KESNDLATSG LTHPEGPYGS AATSTTNPEF VEDLSQGQLL
QSEASNAVEG NEQRPEDEQR SKRGGWSKGR KRKKPLRDSN APKSPLTGYV RFMNERREQL
RAKRPEVPFP EITRMLGNEW SKLPPEEKQV MVPASGVSLG FDYISEIVWG AGEIWGLGHA
//
