ID A0A1L3J460_9FLAO Unreviewed; 715 AA.
AC A0A1L3J460;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Sodium:proton antiporter {ECO:0000313|EMBL:APG59918.1};
GN ORFNames=LPB144_05605 {ECO:0000313|EMBL:APG59918.1};
OS Christiangramia salexigens.
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC Flavobacteriaceae; Christiangramia.
OX NCBI_TaxID=1913577 {ECO:0000313|EMBL:APG59918.1, ECO:0000313|Proteomes:UP000182510};
RN [1] {ECO:0000313|EMBL:APG59918.1, ECO:0000313|Proteomes:UP000182510}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LPB0144 {ECO:0000313|EMBL:APG59918.1,
RC ECO:0000313|Proteomes:UP000182510};
RA Kim E., Yi H.;
RT "Gramella sp. LPB0144 isolated from marine environment.";
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; CP018153; APG59918.1; -; Genomic_DNA.
DR RefSeq; WP_072552568.1; NZ_CP018153.1.
DR AlphaFoldDB; A0A1L3J460; -.
DR STRING; 1913577.LPB144_05605; -.
DR KEGG; grl:LPB144_05605; -.
DR OrthoDB; 9793589at2; -.
DR Proteomes; UP000182510; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015297; F:antiporter activity; IEA:InterPro.
DR GO; GO:1902600; P:proton transmembrane transport; IEA:InterPro.
DR Gene3D; 1.20.1530.20; -; 1.
DR InterPro; IPR006153; Cation/H_exchanger.
DR InterPro; IPR038770; Na+/solute_symporter_sf.
DR PANTHER; PTHR43562:SF4; NA(+)_H(+) ANTIPORTER NHAS5; 1.
DR PANTHER; PTHR43562; NAPA-TYPE SODIUM/HYDROGEN ANTIPORTER; 1.
DR Pfam; PF00999; Na_H_Exchanger; 1.
DR SUPFAM; SSF52402; Adenine nucleotide alpha hydrolases-like; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000182510};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 16..34
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 41..60
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 66..87
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 99..119
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 125..145
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 157..181
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 193..216
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 228..254
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 274..294
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 306..326
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 338..361
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 373..395
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 21..394
FT /note="Cation/H+ exchanger"
FT /evidence="ECO:0000259|Pfam:PF00999"
SQ SEQUENCE 715 AA; 78886 MW; 07746DDD512CDA5E CRC64;
MIFLILQEIT LPLSNPVLKF LLILVIILIA PLLLNKIKVP ALLGLIIAGA IIGPNGFNLM
ERDSGIILSG TAGLLYIMFL AGLEIDLKDF KDNRNKSMVF GMYTFLIPMG LGILTGLYIL
EFSMLTSVLL ASMFASHTLI AYPIVSKLGV TKNRAVNITI GGTMITDTLA LLVLAVIVGM
AHGEVNVLFW TRLSISILLC GLIIVFLFPI IAKWFFKNFN DNVSQYIFVL VLVFSGAFLA
ELAGIEAIIG AFLTGLSINR LIPHSSPLMN RIEFVGNAIF IPFFLIGVGM LINYKIFFMN
FETIKVGAVM VVVATSAKFI AAWLTQKSFK FTTDERRIIF GLSNAQAAAT LAAVLIGYNI
IIGTTASGED IRLLNETVLN GTILMILVTC TIASFEAQAG AKNIALAGGA SNGFSRLNTD
EKILIPVSNA ENTEELIQLA LSLKSKVNTR GLYALSIVNN NLEPAIAENN SNRLLDIASK
TASATDNHLK KLIRYDLNIL NGITSVLKEQ KITDLILGLH IKKDISDSFL GSLTESILSR
SGSTTFIYKP RQPLGTIKRH LIFIPENAEK EIGFINWVLK IWNLAENTGA QLVFYANDKT
LKILEEINSK HSINCEFKSA SIWDEFISSE FKTREDDNLI IILSRKNKPS FHEKMQKLPS
YLNERFQENG FILVYPIQSG VENSSVSDLF NPSLYDSVGK LEELGKIFSK NWNRS
//
