ID A0A1L3JFT5_9FLAO Unreviewed; 213 AA.
AC A0A1L3JFT5;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Alkyl hydroperoxide reductase {ECO:0000313|EMBL:APG63996.1};
GN ORFNames=LPB136_00815 {ECO:0000313|EMBL:APG63996.1};
OS Tenacibaculum todarodis.
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC Flavobacteriaceae; Tenacibaculum.
OX NCBI_TaxID=1850252 {ECO:0000313|EMBL:APG63996.1, ECO:0000313|Proteomes:UP000181898};
RN [1] {ECO:0000313|EMBL:APG63996.1, ECO:0000313|Proteomes:UP000181898}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LPB0136 {ECO:0000313|EMBL:APG63996.1,
RC ECO:0000313|Proteomes:UP000181898};
RA Kim E., Yi H.;
RT "Tenacibaculum sp. LPB0136, isolated from marine environment.";
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Thiol-specific peroxidase that catalyzes the reduction of
CC hydrogen peroxide and organic hydroperoxides to water and alcohols,
CC respectively. Plays a role in cell protection against oxidative stress
CC by detoxifying peroxides. {ECO:0000256|ARBA:ARBA00037420}.
CC -!- SIMILARITY: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
CC {ECO:0000256|ARBA:ARBA00009796}.
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DR EMBL; CP018155; APG63996.1; -; Genomic_DNA.
DR RefSeq; WP_072554318.1; NZ_CP018155.1.
DR AlphaFoldDB; A0A1L3JFT5; -.
DR STRING; 1850252.LPB136_00815; -.
DR KEGG; ten:LPB136_00815; -.
DR OrthoDB; 9812811at2; -.
DR Proteomes; UP000181898; Chromosome.
DR GO; GO:0051920; F:peroxiredoxin activity; IEA:InterPro.
DR CDD; cd03015; PRX_Typ2cys; 1.
DR Gene3D; 3.40.30.10; Glutaredoxin; 1.
DR InterPro; IPR000866; AhpC/TSA.
DR InterPro; IPR024706; Peroxiredoxin_AhpC-typ.
DR InterPro; IPR019479; Peroxiredoxin_C.
DR InterPro; IPR036249; Thioredoxin-like_sf.
DR InterPro; IPR013766; Thioredoxin_domain.
DR PANTHER; PTHR10681; THIOREDOXIN PEROXIDASE; 1.
DR PANTHER; PTHR10681:SF128; THIOREDOXIN-DEPENDENT PEROXIDE REDUCTASE, MITOCHONDRIAL; 1.
DR Pfam; PF10417; 1-cysPrx_C; 1.
DR Pfam; PF00578; AhpC-TSA; 1.
DR PIRSF; PIRSF000239; AHPC; 1.
DR SUPFAM; SSF52833; Thioredoxin-like; 1.
DR PROSITE; PS51352; THIOREDOXIN_2; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000181898}.
FT DOMAIN 3..180
FT /note="Thioredoxin"
FT /evidence="ECO:0000259|PROSITE:PS51352"
FT ACT_SITE 52
FT /note="Cysteine sulfenic acid (-SOH) intermediate; for
FT peroxidase activity"
FT /evidence="ECO:0000256|PIRSR:PIRSR000239-1"
SQ SEQUENCE 213 AA; 23720 MW; 6758CBCD7B84D04B CRC64;
MATAVGKQFP DLNVDAMNEM GDTFKINVLE EAKNNNKKVL LFWYPKDFTF VCPTELHAFQ
AALGEFEKRN TIVIGASCDT PEVHFAWLNQ SKDNGGIEGV TYPLLADSNR NLSSILGILD
ISEEVYDEAT QTVQVVGDNV TYRATYLIDE EGTVFHEGIN HMPVGRNVNE FLRLIDAYSH
VQKNGEVCPA NWEEGKDAMK PNAKGTAEYL ASH
//