ID A0A1L3MF86_9MICO Unreviewed; 254 AA.
AC A0A1L3MF86;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 24-JAN-2024, entry version 21.
DE RecName: Full=uroporphyrinogen-III C-methyltransferase {ECO:0000256|ARBA:ARBA00012162};
DE EC=2.1.1.107 {ECO:0000256|ARBA:ARBA00012162};
GN Name=cobA {ECO:0000313|EMBL:QOK23808.1};
GN ORFNames=ASJ30_05300 {ECO:0000313|EMBL:APH01025.1}, IGS73_05330
GN {ECO:0000313|EMBL:QOK23808.1};
OS Janibacter indicus.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Intrasporangiaceae;
OC Janibacter.
OX NCBI_TaxID=857417 {ECO:0000313|EMBL:APH01025.1, ECO:0000313|Proteomes:UP000182938};
RN [1] {ECO:0000313|EMBL:APH01025.1, ECO:0000313|Proteomes:UP000182938}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=YFY001 {ECO:0000313|EMBL:APH01025.1,
RC ECO:0000313|Proteomes:UP000182938};
RA Zhang Y., Guo Z.;
RL Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:QOK23808.1, ECO:0000313|Proteomes:UP000593998}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TT2 {ECO:0000313|EMBL:QOK23808.1,
RC ECO:0000313|Proteomes:UP000593998};
RA Lee K., Ganzorig M.;
RT "Janibacter indicus TT2 genome sequence.";
RL Submitted (OCT-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the precorrin methyltransferase family.
CC {ECO:0000256|ARBA:ARBA00005879}.
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DR EMBL; CP013290; APH01025.1; -; Genomic_DNA.
DR EMBL; CP062789; QOK23808.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1L3MF86; -.
DR KEGG; jte:ASJ30_05300; -.
DR Proteomes; UP000182938; Chromosome.
DR Proteomes; UP000593998; Chromosome.
DR GO; GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR GO; GO:0019354; P:siroheme biosynthetic process; IEA:InterPro.
DR CDD; cd11642; SUMT; 1.
DR InterPro; IPR000878; 4pyrrol_Mease.
DR InterPro; IPR035996; 4pyrrol_Methylase_sf.
DR InterPro; IPR014777; 4pyrrole_Mease_sub1.
DR InterPro; IPR014776; 4pyrrole_Mease_sub2.
DR InterPro; IPR006366; CobA/CysG_C.
DR NCBIfam; TIGR01469; cobA_cysG_Cterm; 1.
DR PANTHER; PTHR45790:SF3; S-ADENOSYL-L-METHIONINE-DEPENDENT UROPORPHYRINOGEN III METHYLTRANSFERASE, CHLOROPLASTIC; 1.
DR PANTHER; PTHR45790; SIROHEME SYNTHASE-RELATED; 1.
DR Pfam; PF00590; TP_methylase; 1.
DR SUPFAM; SSF53790; Tetrapyrrole methylase; 1.
PE 3: Inferred from homology;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW ECO:0000313|EMBL:QOK23808.1};
KW Porphyrin biosynthesis {ECO:0000256|ARBA:ARBA00023244};
KW Reference proteome {ECO:0000313|Proteomes:UP000182938};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:QOK23808.1}.
FT DOMAIN 10..222
FT /note="Tetrapyrrole methylase"
FT /evidence="ECO:0000259|Pfam:PF00590"
SQ SEQUENCE 254 AA; 25296 MW; D1108AEBA07623DA CRC64;
MTDATTATGR VILVGGGPGD PGLLTVAGRD ALAAADVVVT DRLGPVAALD EIAPQAEIVH
VGKIPRGEFT PQERINELLV EHARAGRTVV RLKGGDGYLF GRGGEEWNHC VAAGVPVEAV
PGVSSAFSVP ALAGIPVTHR GLSQGVAVVS GHVAPDDPCS EVDWAALATS RLTIVILMGV
ATLGAIAEAL VAAGLSPDTP AACIADGATP QQRSVRAPLS QIASAADEGG FAPPAITVVG
DVVGALDSPA PTSP
//
