ID   A0A1L4BR74_9GAMM        Unreviewed;      1302 AA.
AC   A0A1L4BR74;
DT   15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT   15-MAR-2017, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   SubName: Full=ATP-dependent RNA helicase HrpA {ECO:0000313|EMBL:API86343.1};
GN   ORFNames=F7310_02790 {ECO:0000313|EMBL:API86343.1};
OS   Francisella uliginis.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Thiotrichales;
OC   Francisellaceae; Francisella.
OX   NCBI_TaxID=573570 {ECO:0000313|EMBL:API86343.1, ECO:0000313|Proteomes:UP000184222};
RN   [1] {ECO:0000313|EMBL:API86343.1, ECO:0000313|Proteomes:UP000184222}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=TX077310 {ECO:0000313|EMBL:API86343.1,
RC   ECO:0000313|Proteomes:UP000184222};
RX   PubMed=27881415;
RA   Challacombe J.F., Petersen J.M., Gallegos-Graves V., Hodge D., Pillai S.,
RA   Kuske C.R.;
RT   "Whole genome relationships among Francisella bacteria of diverse origin
RT   define new species and provide specific regions for detection.";
RL   Appl. Environ. Microbiol. 0:0-0(2016).
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DR   EMBL; CP016796; API86343.1; -; Genomic_DNA.
DR   RefSeq; WP_072711600.1; NZ_CP016796.1.
DR   STRING; 573570.F7310_02790; -.
DR   KEGG; frx:F7310_02790; -.
DR   OrthoDB; 9805617at2; -.
DR   Proteomes; UP000184222; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0003724; F:RNA helicase activity; IEA:InterPro.
DR   CDD; cd18791; SF2_C_RHA; 1.
DR   Gene3D; 1.20.120.1080; -; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR011709; DEAD-box_helicase_OB_fold.
DR   InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR   InterPro; IPR007502; Helicase-assoc_dom.
DR   InterPro; IPR014001; Helicase_ATP-bd.
DR   InterPro; IPR001650; Helicase_C.
DR   InterPro; IPR024590; HrpA_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010222; RNA_helicase_HrpA.
DR   NCBIfam; TIGR01967; DEAH_box_HrpA; 1.
DR   PANTHER; PTHR18934; ATP-DEPENDENT RNA HELICASE; 1.
DR   PANTHER; PTHR18934:SF83; PRE-MRNA-SPLICING FACTOR ATP-DEPENDENT RNA HELICASE DHX16; 1.
DR   Pfam; PF00270; DEAD; 1.
DR   Pfam; PF11898; DUF3418; 1.
DR   Pfam; PF21010; HA2_C; 1.
DR   Pfam; PF00271; Helicase_C; 1.
DR   Pfam; PF07717; OB_NTP_bind; 1.
DR   SMART; SM00487; DEXDc; 1.
DR   SMART; SM00847; HA2; 1.
DR   SMART; SM00490; HELICc; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR   PROSITE; PS51194; HELICASE_CTER; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Helicase {ECO:0000313|EMBL:API86343.1};
KW   Hydrolase {ECO:0000313|EMBL:API86343.1};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT   DOMAIN          70..231
FT                   /note="Helicase ATP-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51192"
FT   DOMAIN          252..420
FT                   /note="Helicase C-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS51194"
FT   COILED          1211..1238
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   1302 AA;  150161 MW;  EA746CA4A2B0FCF6 CRC64;
     MPNFKNQASS LLNQISTKLR GKYISLLKRG SVDSKLIKEL NDLAKQTDQK ILPKITYPDL
     PVADKVGDIK KLIDENQVIV VAGETGSGKS TQLPKICLDL GLGKRGLIGH TQPRRIAARS
     IANRVASEIG DQSKVSFKIR FSDQTSENTL IKVMTDGVLL SEIKNDRFLS QYEVIIIDEA
     HERSLNIDFL LGCIKKILPF RPDLKVIITS ATIDHQKFTS YFQKSKEIAV SGRTYPVEIC
     YQNDEDFDEF SMQERILYAI DELGKGDVLV FLPTERDIHE TLAYLNKQDL RFTEVLPLFS
     RLSNKDQNKI FNPESSTRRI ILATNVAETS LTVPRIKYVI DSGLARVSRY SYRTKVQRLP
     IEKISQASAN QRAGRCGRLS AGVCIRLYSE EDFNNRKEYT DPEILRTNLA SVILQMLFLK
     LGSIQEFPFI DPPDSKFVKD GFKLLFELQA ISELNYSKPK ITADGIKMAI MPLDPKLAKI
     VIEGHRQKAL KEIVSIVSFL SVQDPRERPL SFQQKADEKH SIDKDKSSDF IAILNLANRL
     NSDLKGLSNR EKKDYYKKNF ISPVRFNEWN DIYRQIVEVI HGFGWKLGYQ GEVDKKACHS
     EQVAERSRST GSHLIREIPD QVRNDDKGNI KYENLHKAIA SGFLSNIGFN YENAEYLGAR
     GLKFFIFPGS SQFKRKPKWL LSSEIVETTK TYARNVAKIE PEWLEALAKH LVKKHYDEPT
     WSKKRRAVVV NERITLYGLE IISKRSVQYS RINPQEAREI FIREALVNGD FESKVYFYQQ
     NLKLIEQVED LENKSRRKDI LVDEQVMYQH YDELMPEDVC SGVTFDKWLK TISKNEQQKL
     VFDLDSLMQH SAEGITQQKF PDVLAVGDMH LPLEYHFDPL DERDGATVTV PIVFLNDINP
     SVLEWGIYGF LYDKIIALLR ALPKNIRKNC VPVPTYAQAI FESIDFEVDK YKPLKSIIAK
     HITRMVGFIV DETVWQNEEL EKHLVLNIKV VDENGEELAI DKDIHVLKQK LQNLVQKPRL
     TTNDKIYYDW EFGNIEQNSQ IKEYGINVKV YNCLEISKDG VKLSYKATIE EAHSCMKKAL
     KKLIKLRLQN HLSNSIKKND LASLSMSLKL NNSKDDIVDK AIDLSFFDNI ELPYTKAGFE
     KLYSNGFEKF DLNRSKVESL VSEIIKYKNQ LEKKLNVKKI PFNFIQLYTD VKSELGEIFV
     GDYLSQPIKF LQRYKYYIQA LENRLEKAKL NLQRDKVYQI EVDELRSRLD KKIKAKHLNS
     ESSEVIKVNF LIKELWVSWY LQNIKTIESV SYKKILTCIN GI
//