ID A0A1L4BUB3_9GAMM Unreviewed; 405 AA.
AC A0A1L4BUB3;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Beta-ketoacyl-ACP synthase II {ECO:0000313|EMBL:API87433.1};
GN ORFNames=F7310_08700 {ECO:0000313|EMBL:API87433.1};
OS Francisella uliginis.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Thiotrichales;
OC Francisellaceae; Francisella.
OX NCBI_TaxID=573570 {ECO:0000313|EMBL:API87433.1, ECO:0000313|Proteomes:UP000184222};
RN [1] {ECO:0000313|EMBL:API87433.1, ECO:0000313|Proteomes:UP000184222}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TX077310 {ECO:0000313|EMBL:API87433.1,
RC ECO:0000313|Proteomes:UP000184222};
RX PubMed=27881415;
RA Challacombe J.F., Petersen J.M., Gallegos-Graves V., Hodge D., Pillai S.,
RA Kuske C.R.;
RT "Whole genome relationships among Francisella bacteria of diverse origin
RT define new species and provide specific regions for detection.";
RL Appl. Environ. Microbiol. 0:0-0(2016).
CC -!- PATHWAY: Lipid metabolism; fatty acid biosynthesis.
CC {ECO:0000256|ARBA:ARBA00005194}.
CC -!- SIMILARITY: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP
CC synthases family. {ECO:0000256|ARBA:ARBA00008467,
CC ECO:0000256|RuleBase:RU003694}.
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DR EMBL; CP016796; API87433.1; -; Genomic_DNA.
DR RefSeq; WP_072713214.1; NZ_CP016796.1.
DR AlphaFoldDB; A0A1L4BUB3; -.
DR STRING; 573570.F7310_08700; -.
DR KEGG; frx:F7310_08700; -.
DR OrthoDB; 9808669at2; -.
DR UniPathway; UPA00094; -.
DR Proteomes; UP000184222; Chromosome.
DR GO; GO:0004315; F:3-oxoacyl-[acyl-carrier-protein] synthase activity; IEA:InterPro.
DR GO; GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-UniPathway.
DR CDD; cd00834; KAS_I_II; 1.
DR Gene3D; 3.40.47.10; -; 1.
DR InterPro; IPR000794; Beta-ketoacyl_synthase.
DR InterPro; IPR018201; Ketoacyl_synth_AS.
DR InterPro; IPR014031; Ketoacyl_synth_C.
DR InterPro; IPR014030; Ketoacyl_synth_N.
DR InterPro; IPR020841; PKS_Beta-ketoAc_synthase_dom.
DR InterPro; IPR016039; Thiolase-like.
DR PANTHER; PTHR11712:SF325; 3-OXOACYL-(ACYL-CARRIER-PROTEIN) SYNTHASE II FABF; 1.
DR PANTHER; PTHR11712; POLYKETIDE SYNTHASE-RELATED; 1.
DR Pfam; PF00109; ketoacyl-synt; 1.
DR Pfam; PF02801; Ketoacyl-synt_C; 1.
DR SMART; SM00825; PKS_KS; 1.
DR SUPFAM; SSF53901; Thiolase-like; 2.
DR PROSITE; PS00606; KS3_1; 1.
DR PROSITE; PS52004; KS3_2; 1.
PE 3: Inferred from homology;
KW Fatty acid biosynthesis {ECO:0000256|ARBA:ARBA00023160};
KW Fatty acid metabolism {ECO:0000256|ARBA:ARBA00022832};
KW Lipid biosynthesis {ECO:0000256|ARBA:ARBA00023160};
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00023160};
KW Transferase {ECO:0000256|RuleBase:RU003694}.
FT DOMAIN 1..404
FT /note="Ketosynthase family 3 (KS3)"
FT /evidence="ECO:0000259|PROSITE:PS52004"
SQ SEQUENCE 405 AA; 43394 MW; 2D12368CB0B863B1 CRC64;
MHRVVVTGMS GVTALGNDID TIFDSLLAGK TAIKRMPWDD IQGLNTKLAA PITNFKTPNY
PRKKVRGMGL VSKLATVATE QALEDAGLLD QTDILTKGRT GVAYGSCSGS PQPLSDLLMI
LTDKKIGNVN ATTYIKGMSH TCAVNVALFF GLTGRLIPTS SACTSSSQAI GYAYEAIKYG
MQDVMVAGGA EELCISQVAI FDTLFATSQM NDTPSIAQKP FDRDRDGLVI GEGGATLILE
SLEHAQQRGA KIYAEVVGYG TNCDAQHVTQ PTAEKMQIAL NLALEDAQIT PDMIGYVNAH
GTSTEIGDIA ESIATREVFN RDVNISSLKG YFGHTLGASG SLEALLTIEM MNRGVFISNA
NLKNVDSRCA SLNYLVNNQH IDTEYVMTNN FAFGGVNTSL IFKKF
//
