ID A0A1L5JHI3_DELLE Unreviewed; 69 AA.
AC A0A1L5JHI3;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE RecName: Full=Guanine nucleotide-binding protein subunit gamma {ECO:0000256|RuleBase:RU004973};
GN Name=GNGT2 {ECO:0000313|EMBL:APO14191.1,
GN ECO:0000313|RefSeq:XP_022413600.1, ECO:0000313|RefSeq:XP_022413601.1,
GN ECO:0000313|RefSeq:XP_022413602.1, ECO:0000313|RefSeq:XP_022413603.1,
GN ECO:0000313|RefSeq:XP_022413604.1, ECO:0000313|RefSeq:XP_022413605.1};
OS Delphinapterus leucas (Beluga whale).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC Monodontidae; Delphinapterus.
OX NCBI_TaxID=9749 {ECO:0000313|EMBL:APO14191.1};
RN [1] {ECO:0000313|EMBL:APO14191.1}
RP NUCLEOTIDE SEQUENCE.
RA Springer M.S., Emerling C.A., Fugate N., Patel R., Starrett J., Morin P.A.,
RA Hayashi C., Gatesy J.;
RT "Inactivation of cone-specific phototransduction genes in rod monochromatic
RT cetaceans.";
RL Front Ecol Evol 0:0-0(2017).
RN [2] {ECO:0000313|RefSeq:XP_022413600.1, ECO:0000313|RefSeq:XP_022413601.1}
RP IDENTIFICATION.
RC TISSUE=Blood {ECO:0000313|RefSeq:XP_022413600.1,
RC ECO:0000313|RefSeq:XP_022413601.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: Guanine nucleotide-binding proteins (G proteins) are involved
CC as a modulator or transducer in various transmembrane signaling
CC systems. The beta and gamma chains are required for the GTPase
CC activity, for replacement of GDP by GTP, and for G protein-effector
CC interaction. {ECO:0000256|RuleBase:RU004973}.
CC -!- SUBUNIT: G proteins are composed of 3 units; alpha, beta and gamma.
CC {ECO:0000256|RuleBase:RU004973}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU004973};
CC Lipid-anchor {ECO:0000256|RuleBase:RU004973}; Cytoplasmic side
CC {ECO:0000256|RuleBase:RU004973}.
CC -!- SIMILARITY: Belongs to the G protein gamma family.
CC {ECO:0000256|ARBA:ARBA00007431, ECO:0000256|RuleBase:RU004973}.
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DR EMBL; KX118317; APO14191.1; -; Genomic_DNA.
DR RefSeq; XP_022413600.1; XM_022557892.1.
DR RefSeq; XP_022413601.1; XM_022557893.2.
DR RefSeq; XP_022413602.1; XM_022557894.2.
DR RefSeq; XP_022413603.1; XM_022557895.2.
DR RefSeq; XP_022413604.1; XM_022557896.2.
DR RefSeq; XP_022413605.1; XM_022557897.2.
DR STRING; 9749.A0A1L5JHI3; -.
DR Ensembl; ENSDLET00000007359; ENSDLEP00000006638; ENSDLEG00000004944.
DR KEGG; dle:111166309; -.
DR OrthoDB; 5344095at2759; -.
DR Proteomes; UP000248483; Unplaced.
DR GO; GO:0005834; C:heterotrimeric G-protein complex; IEA:Ensembl.
DR GO; GO:0031681; F:G-protein beta-subunit binding; IEA:InterPro.
DR GO; GO:0003924; F:GTPase activity; IEA:Ensembl.
DR GO; GO:0007186; P:G protein-coupled receptor signaling pathway; IEA:InterPro.
DR CDD; cd00068; GGL; 1.
DR Gene3D; 4.10.260.10; Transducin (heterotrimeric G protein), gamma chain; 1.
DR InterPro; IPR015898; G-protein_gamma-like_dom.
DR InterPro; IPR036284; GGL_sf.
DR InterPro; IPR001770; Gprotein-gamma.
DR PANTHER; PTHR13809:SF28; GUANINE NUCLEOTIDE-BINDING PROTEIN G(I)_G(S)_G(O) SUBUNIT GAMMA-T2; 1.
DR PANTHER; PTHR13809; GUANINE NUCLEOTIDE-BINDING PROTEIN GAMMA SUBUNIT; 1.
DR Pfam; PF00631; G-gamma; 1.
DR PRINTS; PR00321; GPROTEING.
DR SMART; SM01224; G_gamma; 1.
DR SMART; SM00224; GGL; 1.
DR SUPFAM; SSF48670; Transducin (heterotrimeric G protein), gamma chain; 1.
DR PROSITE; PS50058; G_PROTEIN_GAMMA; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW ECO:0000256|RuleBase:RU004973};
KW Lipoprotein {ECO:0000256|RuleBase:RU004973};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU004973};
KW Reference proteome {ECO:0000313|Proteomes:UP000248483};
KW Transducer {ECO:0000256|ARBA:ARBA00023224, ECO:0000256|RuleBase:RU004973}.
FT DOMAIN 1..69
FT /note="G protein gamma"
FT /evidence="ECO:0000259|PROSITE:PS50058"
FT REGION 47..69
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 69 AA; 7730 MW; 21165EB47D520314 CRC64;
MAQELSEKEL LKMEVEQLKK EVKNPRAPIS KTGKEIKDYV EAEAGNDPLL KGIPEDKNPF
KEKGGCMIS
//
