ID A0A1L6HVT8_9BURK Unreviewed; 970 AA.
AC A0A1L6HVT8;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 24-JAN-2024, entry version 25.
DE SubName: Full=Competence protein ComEC {ECO:0000313|EMBL:APR35562.1};
GN ORFNames=BTO02_09145 {ECO:0000313|EMBL:APR35562.1};
OS Paraburkholderia sp. SOS3.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Paraburkholderia.
OX NCBI_TaxID=1926494 {ECO:0000313|EMBL:APR35562.1, ECO:0000313|Proteomes:UP000184708};
RN [1] {ECO:0000313|EMBL:APR35562.1, ECO:0000313|Proteomes:UP000184708}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SOS3 {ECO:0000313|EMBL:APR35562.1,
RC ECO:0000313|Proteomes:UP000184708};
RA Song W.-J., Kurnit D.M.;
RL Submitted (DEC-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; CP018811; APR35562.1; -; Genomic_DNA.
DR RefSeq; WP_075156772.1; NZ_CP018811.1.
DR AlphaFoldDB; A0A1L6HVT8; -.
DR STRING; 1926494.BTO02_09145; -.
DR KEGG; para:BTO02_09145; -.
DR Proteomes; UP000184708; Chromosome 1.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR CDD; cd07731; ComA-like_MBL-fold; 1.
DR Gene3D; 3.60.15.10; Ribonuclease Z/Hydroxyacylglutathione hydrolase-like; 1.
DR InterPro; IPR035681; ComA-like_MBL.
DR InterPro; IPR004477; ComEC_N.
DR InterPro; IPR025405; DUF4131.
DR InterPro; IPR001279; Metallo-B-lactamas.
DR InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR NCBIfam; TIGR00360; ComEC_N-term; 1.
DR PANTHER; PTHR30619; DNA INTERNALIZATION/COMPETENCE PROTEIN COMEC/REC2; 1.
DR PANTHER; PTHR30619:SF1; RECOMBINATION PROTEIN 2; 1.
DR Pfam; PF03772; Competence; 1.
DR Pfam; PF13567; DUF4131; 2.
DR Pfam; PF00753; Lactamase_B; 1.
DR SMART; SM00849; Lactamase_B; 1.
DR SUPFAM; SSF56281; Metallo-hydrolase/oxidoreductase; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 25..45
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 57..77
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 328..351
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 400..429
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 435..455
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 534..553
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 565..587
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 599..618
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 679..908
FT /note="Metallo-beta-lactamase"
FT /evidence="ECO:0000259|SMART:SM00849"
FT REGION 116..172
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 123..154
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 970 AA; 103251 MW; 79264758377669B4 CRC64;
MRAVWCGFAL GVVWLQQQAA LPERFGAALL ALAACGALGV AIWGLRRRGS ACMTCRRAAW
CAIWLAAFCV GFGYAAWRAH ARLAYALPVE WEGRDVEVRG YIEGLPTLLA DSAGSRARNA
GGKNGRNVED AREDAGARDK DGGKDGRKDG GKAGDEAANS AGKGAADGAG RRAGNIGDTG
LRFIFNVEAT DTPVPHFPRR LQLSWIAQDA PLPQGLGPGA RWRLFVRLKR AHGNANFGVR
DAEATLFARN IRATGYVTHP ASAQRLPGDA RGIGMTVDRW RAALRARIDG VLADAPHRGI
VVALAIGAQD AVSAADWQLM RATGTSHLVA ISGLHIGFVA GLAAWLAGAI WRRSGFVGAR
IGIDWPLVLP AQKVAAPCGA LFAAFHAALA GFNVPAQRAL WMLAVVALAF VSGRAVAPSV
VLAWALGLVL LIDPWAVLAA GFWLSFCAVA AILFAMSGRA AVRADDNGRP RYGSLDDEDG
LNAGAPHEDR RLGDAHERLT RRAFRTRLLS LATALRLRAR TLTHAFVERM RSGAYVQFAV
TVALAPLTAY WFAQIPLIGP LANAFAIPWV SVLVTPLVLA GVALPAPLDA FAFSVAHRLL
GVLTAGLHLV SGHAWALWRL PQPDAWALAA AAAGVIWCLA PRGWPMRWAA PIAWLPLLMP
PPSAPPHGTF RLTALDIGQG SAIVVETAHH ALLFDAGPGP ESTHAGERVV VPYLQAAGVQ
TLDTLVISHA DSDHSGGAAA VLDGVAVRQL LAALPPDHML WHSARAAGAG TVPCAAGQRW
QWDGVEFAML WPDAGPLRGK PNAHCCVLRV SASASTDYDA AERAVDDAAR AHANLGAGID
AHADARPRAT ALLTADIEAA VERTLLARDR DALRAQVLLA PHHGSKTSST EPFLDAIDPL
IAIFQVGYRN RFHHPHPGVF ARYVARHIEL PRSDEDGAVR IEASADALGK DRLVLTLERY
RKTHRRYWMD
//
