ID A0A1L6I5Y0_9BURK Unreviewed; 394 AA.
AC A0A1L6I5Y0;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Acetyl-CoA acetyltransferase {ECO:0000313|EMBL:APR38640.1};
GN ORFNames=BTO02_24690 {ECO:0000313|EMBL:APR38640.1};
OS Paraburkholderia sp. SOS3.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Paraburkholderia.
OX NCBI_TaxID=1926494 {ECO:0000313|EMBL:APR38640.1, ECO:0000313|Proteomes:UP000184708};
RN [1] {ECO:0000313|EMBL:APR38640.1, ECO:0000313|Proteomes:UP000184708}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SOS3 {ECO:0000313|EMBL:APR38640.1,
RC ECO:0000313|Proteomes:UP000184708};
RA Song W.-J., Kurnit D.M.;
RL Submitted (DEC-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the thiolase-like superfamily. Thiolase family.
CC {ECO:0000256|ARBA:ARBA00010982, ECO:0000256|RuleBase:RU003557}.
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DR EMBL; CP018812; APR38640.1; -; Genomic_DNA.
DR RefSeq; WP_075159812.1; NZ_CP018812.1.
DR AlphaFoldDB; A0A1L6I5Y0; -.
DR STRING; 1926494.BTO02_24690; -.
DR KEGG; para:BTO02_24690; -.
DR OrthoDB; 8558405at2; -.
DR Proteomes; UP000184708; Chromosome 2.
DR GO; GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups; IEA:InterPro.
DR CDD; cd00751; thiolase; 1.
DR Gene3D; 3.40.47.10; -; 2.
DR InterPro; IPR002155; Thiolase.
DR InterPro; IPR016039; Thiolase-like.
DR InterPro; IPR020610; Thiolase_AS.
DR InterPro; IPR020617; Thiolase_C.
DR InterPro; IPR020613; Thiolase_CS.
DR InterPro; IPR020616; Thiolase_N.
DR NCBIfam; TIGR01930; AcCoA-C-Actrans; 1.
DR PANTHER; PTHR18919; ACETYL-COA C-ACYLTRANSFERASE; 1.
DR PANTHER; PTHR18919:SF153; TRIFUNCTIONAL ENZYME SUBUNIT BETA, MITOCHONDRIAL; 1.
DR Pfam; PF02803; Thiolase_C; 1.
DR Pfam; PF00108; Thiolase_N; 1.
DR PIRSF; PIRSF000429; Ac-CoA_Ac_transf; 1.
DR SUPFAM; SSF53901; Thiolase-like; 2.
DR PROSITE; PS00737; THIOLASE_2; 1.
DR PROSITE; PS00099; THIOLASE_3; 1.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000256|RuleBase:RU003557};
KW Transferase {ECO:0000256|RuleBase:RU003557, ECO:0000313|EMBL:APR38640.1}.
FT DOMAIN 6..262
FT /note="Thiolase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00108"
FT DOMAIN 272..392
FT /note="Thiolase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02803"
FT ACT_SITE 90
FT /note="Acyl-thioester intermediate"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
FT ACT_SITE 350
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
FT ACT_SITE 380
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
SQ SEQUENCE 394 AA; 41732 MW; E5AAEE1C09A58017 CRC64;
MTTREIVISN PVRTAIGAFG GTLKDVPATD LGALVVREAV RRSGFDASRL GSVVMGNVVQ
AGNRMNPARQ AAIAGGVPVS VPSQTVNRVC GSGAQAVVSA AHEIWLGFGE VAVAGGMENM
DRAPYLLDKG RWGYRMGNAQ IYDSALHDGL VDAFSSEHSG WHTEDLVTKL SITREAQDRW
AARSHQRFAA AQKRGAFEAE RVAVEVQGRK EAIRFTDDEQ LRPDTTVETL AKLRPAFRRD
GTITAGNAPG LNSGAAAMLV AERGYAEANG IEPHARLVAY GIGAVEPGMF GLGPVPAVRM
AVERADWKLT DVERFEINEA FAAVPLAIIQ QLGLAEDVVN VEGGAVAHGH PIGATGAILT
TRLIHSMRRD GLKRGVVTLC IGGGQGIALA LEMF
//
