ID A0A1L6JBD7_9SPHN Unreviewed; 676 AA.
AC A0A1L6JBD7;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=3-hydroxyacyl-CoA dehydrogenase {ECO:0000313|EMBL:APR52820.1};
GN ORFNames=BRX38_04160 {ECO:0000313|EMBL:RSU44323.1}, BRX39_03390
GN {ECO:0000313|EMBL:RSU38162.1}, BRX40_10645
GN {ECO:0000313|EMBL:APR52820.1}, CA221_06245
GN {ECO:0000313|EMBL:RSU51988.1}, CA222_04580
GN {ECO:0000313|EMBL:RSU28349.1}, CA223_09795
GN {ECO:0000313|EMBL:RSU40227.1}, CA224_13370
GN {ECO:0000313|EMBL:RSU19329.1}, CA225_04405
GN {ECO:0000313|EMBL:RSU31330.1}, CA226_04630
GN {ECO:0000313|EMBL:RSV65225.1}, CA227_01900
GN {ECO:0000313|EMBL:RSX15945.1}, CA228_01595
GN {ECO:0000313|EMBL:RSV61923.1}, CA229_14960
GN {ECO:0000313|EMBL:RSV54064.1}, CA230_15015
GN {ECO:0000313|EMBL:RSW93606.1}, CA231_17785
GN {ECO:0000313|EMBL:RSV44063.1}, CA232_10165
GN {ECO:0000313|EMBL:RSV36515.1}, CA238_07940
GN {ECO:0000313|EMBL:RSV25232.1}, CA239_09020
GN {ECO:0000313|EMBL:RSV29254.1}, CA240_04585
GN {ECO:0000313|EMBL:RSV09704.1}, CA242_08150
GN {ECO:0000313|EMBL:RSV10109.1}, CA253_09790
GN {ECO:0000313|EMBL:RSU88415.1}, CA256_04135
GN {ECO:0000313|EMBL:RSU97901.1}, CA257_08340
GN {ECO:0000313|EMBL:RSV04074.1}, DAH52_08955
GN {ECO:0000313|EMBL:RSU95535.1}, DAH53_10260
GN {ECO:0000313|EMBL:RSU80892.1}, DAH54_09215
GN {ECO:0000313|EMBL:RSU81967.1}, DAH57_07295
GN {ECO:0000313|EMBL:RSZ20732.1}, DAH58_12110
GN {ECO:0000313|EMBL:RSZ13681.1}, DAH59_12715
GN {ECO:0000313|EMBL:RSY97368.1}, DAH60_13565
GN {ECO:0000313|EMBL:RSZ09286.1}, DAH61_07170
GN {ECO:0000313|EMBL:RSZ01939.1}, DAH62_20835
GN {ECO:0000313|EMBL:RSY90898.1}, DAH63_06780
GN {ECO:0000313|EMBL:RSZ11690.1}, DAH64_01085
GN {ECO:0000313|EMBL:RSY86249.1}, DAH65_02805
GN {ECO:0000313|EMBL:RSY89016.1}, DAH67_04820
GN {ECO:0000313|EMBL:RSY74126.1}, DAH68_03475
GN {ECO:0000313|EMBL:RSY73730.1}, DAH69_13225
GN {ECO:0000313|EMBL:RSY60714.1}, DAH70_12450
GN {ECO:0000313|EMBL:RSY55073.1}, DAH71_14030
GN {ECO:0000313|EMBL:RSY52694.1}, DAH72_09250
GN {ECO:0000313|EMBL:RSY68503.1}, DAH73_07960
GN {ECO:0000313|EMBL:RSY35380.1}, DAH74_11430
GN {ECO:0000313|EMBL:RSY45157.1}, DAH75_08585
GN {ECO:0000313|EMBL:RSY40087.1}, DAH76_04035
GN {ECO:0000313|EMBL:RSY49290.1}, DAH77_11645
GN {ECO:0000313|EMBL:RSY23781.1}, DAH78_04035
GN {ECO:0000313|EMBL:RSY14881.1}, DAH79_07070
GN {ECO:0000313|EMBL:RSY29548.1}, DAH80_05755
GN {ECO:0000313|EMBL:RSY22787.1}, DAH81_07045
GN {ECO:0000313|EMBL:RSY15141.1}, DAH82_05190
GN {ECO:0000313|EMBL:RSY02420.1}, DAH83_02310
GN {ECO:0000313|EMBL:RSY09705.1}, DAH84_09925
GN {ECO:0000313|EMBL:RSX83144.1}, DAH85_02300
GN {ECO:0000313|EMBL:RSX95666.1}, DAH86_02685
GN {ECO:0000313|EMBL:RSX91072.1}, DAH87_12995
GN {ECO:0000313|EMBL:RSX94975.1}, DAH88_05940
GN {ECO:0000313|EMBL:RSX67312.1}, DAH89_13635
GN {ECO:0000313|EMBL:RSX72311.1}, DAH90_04360
GN {ECO:0000313|EMBL:RSX80838.1}, DAH91_04170
GN {ECO:0000313|EMBL:RSX64112.1}, DAH92_18195
GN {ECO:0000313|EMBL:RSX63780.1}, DAH93_10195
GN {ECO:0000313|EMBL:RSX45784.1}, DAH94_06055
GN {ECO:0000313|EMBL:RSX43589.1}, DAH95_14370
GN {ECO:0000313|EMBL:RSX37160.1}, DAH96_03510
GN {ECO:0000313|EMBL:RSX23379.1}, DAH97_16020
GN {ECO:0000313|EMBL:RSX27978.1}, DAH98_06645
GN {ECO:0000313|EMBL:RSX29061.1}, DAH99_17325
GN {ECO:0000313|EMBL:RSX19977.1}, DAI00_15205
GN {ECO:0000313|EMBL:RSX06757.1}, DAI01_01090
GN {ECO:0000313|EMBL:RSX10900.1};
OS Sphingomonas koreensis.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
OC Sphingomonadaceae; Sphingomonas.
OX NCBI_TaxID=93064 {ECO:0000313|EMBL:APR52820.1, ECO:0000313|Proteomes:UP000185161};
RN [1] {ECO:0000313|EMBL:APR52820.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=ABOJV {ECO:0000313|EMBL:APR52820.1};
RA Conlan S., Thomas P.J., Mullikin J., Palmore T.N., Frank K.M., Segre J.A.;
RT "Whole genome sequencing of Sphingomonas koreensis.";
RL Submitted (DEC-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000185161}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ABOJV {ECO:0000313|Proteomes:UP000185161};
RA Conlan S., Thomas P.J., Mullikin J., Palmore T.N., Frank K.M., Segre J.A.;
RT "Whole genome sequencing of Sphingomonas sp. ABOJV.";
RL Submitted (DEC-2016) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Proteomes:UP000286970, ECO:0000313|Proteomes:UP000287271}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SK-NIH.Env2_1116 {ECO:0000313|EMBL:RSU28349.1,
RC ECO:0000313|Proteomes:UP000286970}, SK-NIH.Env3_1116
RC {ECO:0000313|EMBL:RSU40227.1, ECO:0000313|Proteomes:UP000287271},
RC SK-NIH.Env4_1116 {ECO:0000313|EMBL:RSU19329.1,
RC ECO:0000313|Proteomes:UP000287347}, SK-NIH.Env8_1116
RC {ECO:0000313|EMBL:RSU31330.1, ECO:0000313|Proteomes:UP000287976},
RC SK-NIH.Pt2_0716 {ECO:0000313|EMBL:RSU44323.1,
RC ECO:0000313|Proteomes:UP000287307}, SK-NIH.Pt4_0816
RC {ECO:0000313|EMBL:RSU38162.1, ECO:0000313|Proteomes:UP000287414}, and
RC SK-NIH.Pt6_1016 {ECO:0000313|EMBL:RSU51988.1,
RC ECO:0000313|Proteomes:UP000287315};
RA Johnson R.C., Deming C., Conlan S., Zellmer C., Michelin A., Lee-Lin S.-Q.,
RA Thomas P.J., Park M., Weingarten R.A., Less J., Dekker J.P., Frank K.M.,
RA Musser K.A., Mcquiston J.R., Henderson D.K., Lau A.F., Palmore T.N.,
RA Segre J.A.;
RT "Genomic and Epidemiologic Investigation to Identify Sphingomonas koreensis
RT Point Sources in an Indolent Hospital Outbreak.";
RL Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases.
RN [4] {ECO:0000313|Proteomes:UP000286706, ECO:0000313|Proteomes:UP000286739}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SK-NIH.Env13_0417 {ECO:0000313|EMBL:RSZ13681.1,
RC ECO:0000313|Proteomes:UP000287513}, SK-NIH.Env14_0417
RC {ECO:0000313|EMBL:RSY97368.1, ECO:0000313|Proteomes:UP000288569},
RC SK-NIH.Env16_0517 {ECO:0000313|EMBL:RSZ09286.1,
RC ECO:0000313|Proteomes:UP000287015}, SK-NIH.Env17_0517
RC {ECO:0000313|EMBL:RSZ20732.1, ECO:0000313|Proteomes:UP000287799},
RC SK-NIH.Env18_0517 {ECO:0000313|EMBL:RSZ01939.1,
RC ECO:0000313|Proteomes:UP000288230}, SK-NIH.Env19_0617
RC {ECO:0000313|EMBL:RSY86249.1, ECO:0000313|Proteomes:UP000288258},
RC SK-NIH.Env20_0617 {ECO:0000313|EMBL:RSY89016.1,
RC ECO:0000313|Proteomes:UP000287482}, SK-NIH.Env21_0617
RC {ECO:0000313|EMBL:RSY90898.1, ECO:0000313|Proteomes:UP000287363},
RC SK-NIH.Env22_0617 {ECO:0000313|EMBL:RSZ11690.1,
RC ECO:0000313|Proteomes:UP000287001}, SK-NIH.Env23_0717
RC {ECO:0000313|EMBL:RSY74126.1, ECO:0000313|Proteomes:UP000287360},
RC SK-NIH.Env24_0717 {ECO:0000313|EMBL:RSY73730.1,
RC ECO:0000313|Proteomes:UP000287229}, SK-NIH.Env25_0717
RC {ECO:0000313|EMBL:RSY60714.1, ECO:0000313|Proteomes:UP000288269},
RC SK-NIH.Env26_0717 {ECO:0000313|EMBL:RSY55073.1,
RC ECO:0000313|Proteomes:UP000287417}, SK-NIH.Env27_0717
RC {ECO:0000313|EMBL:RSY52694.1, ECO:0000313|Proteomes:UP000286788},
RC SK-NIH.Env28_0717 {ECO:0000313|EMBL:RSY68503.1,
RC ECO:0000313|Proteomes:UP000288630}, SK-NIH.Env29_0717
RC {ECO:0000313|EMBL:RSY35380.1, ECO:0000313|Proteomes:UP000287038},
RC SK-NIH.Env30_0717 {ECO:0000313|EMBL:RSY45157.1,
RC ECO:0000313|Proteomes:UP000288207}, SK-NIH.Env31_0717
RC {ECO:0000313|EMBL:RSY40087.1, ECO:0000313|Proteomes:UP000287340},
RC SK-NIH.Env32_0717 {ECO:0000313|EMBL:RSY49290.1,
RC ECO:0000313|Proteomes:UP000288007}, SK-NIH.Env33_0717
RC {ECO:0000313|EMBL:RSY23781.1, ECO:0000313|Proteomes:UP000287541},
RC SK-NIH.Env34_0717 {ECO:0000313|EMBL:RSY14881.1,
RC ECO:0000313|Proteomes:UP000288649}, SK-NIH.Env35_0717
RC {ECO:0000313|EMBL:RSY29548.1, ECO:0000313|Proteomes:UP000287968},
RC SK-NIH.Env36_0717 {ECO:0000313|EMBL:RSY02420.1,
RC ECO:0000313|Proteomes:UP000288516}, SK-NIH.Env37_0717
RC {ECO:0000313|EMBL:RSY22787.1, ECO:0000313|Proteomes:UP000287028},
RC SK-NIH.Env38_0817 {ECO:0000313|EMBL:RSY15141.1,
RC ECO:0000313|Proteomes:UP000287257}, SK-NIH.Env39_0817
RC {ECO:0000313|EMBL:RSY09705.1, ECO:0000313|Proteomes:UP000287073},
RC SK-NIH.Env40_0817 {ECO:0000313|EMBL:RSX83144.1,
RC ECO:0000313|Proteomes:UP000288050}, SK-NIH.Env41_0817
RC {ECO:0000313|EMBL:RSX95666.1, ECO:0000313|Proteomes:UP000286739},
RC SK-NIH.Env42_0817 {ECO:0000313|EMBL:RSX91072.1,
RC ECO:0000313|Proteomes:UP000288181}, SK-NIH.Env43_0817
RC {ECO:0000313|EMBL:RSX94975.1, ECO:0000313|Proteomes:UP000286795},
RC SK-NIH.Env44_0817 {ECO:0000313|EMBL:RSX67312.1,
RC ECO:0000313|Proteomes:UP000286792}, SK-NIH.Env45_1017
RC {ECO:0000313|EMBL:RSX72311.1, ECO:0000313|Proteomes:UP000286760},
RC SK-NIH.Env46_1017 {ECO:0000313|EMBL:RSX63780.1,
RC ECO:0000313|Proteomes:UP000287577}, SK-NIH.Env47_1017
RC {ECO:0000313|EMBL:RSX45784.1, ECO:0000313|Proteomes:UP000288581},
RC SK-NIH.Env48_1017 {ECO:0000313|EMBL:RSX80838.1,
RC ECO:0000313|Proteomes:UP000287090}, SK-NIH.Env49_1017
RC {ECO:0000313|EMBL:RSX64112.1, ECO:0000313|Proteomes:UP000286744},
RC SK-NIH.Env50_1017 {ECO:0000313|EMBL:RSX43589.1,
RC ECO:0000313|Proteomes:UP000288198}, SK-NIH.Env51_1017
RC {ECO:0000313|EMBL:RSX37160.1, ECO:0000313|Proteomes:UP000287844},
RC SK-NIH.Env52_1017 {ECO:0000313|EMBL:RSX23379.1,
RC ECO:0000313|Proteomes:UP000287083}, SK-NIH.Env53_1017
RC {ECO:0000313|EMBL:RSX27978.1, ECO:0000313|Proteomes:UP000288435},
RC SK-NIH.Env54_1217 {ECO:0000313|EMBL:RSX19977.1,
RC ECO:0000313|Proteomes:UP000288203}, SK-NIH.Env55_1217
RC {ECO:0000313|EMBL:RSX06757.1, ECO:0000313|Proteomes:UP000286706},
RC SK-NIH.Env56_1217 {ECO:0000313|EMBL:RSX10900.1,
RC ECO:0000313|Proteomes:UP000287020}, and SK-NIH.Env57_1217
RC {ECO:0000313|EMBL:RSX29061.1, ECO:0000313|Proteomes:UP000287236};
RA Johnson R.C., Deming C., Conlan S., Zellmer C.J., Michelin A.V.,
RA Lee-Lin S.-Q., Thomas P.J., Park M., Weingarten R.A., Less J., Dekker J.P.,
RA Frank K.M., Musser K.A., Mcquiston J.R., Henderson D.K., Lau A.F.,
RA Palmore T.N., Segre J.A.;
RT "Genomic and Epidemiologic Investigation of an Indolent Hospital
RT Outbreak.";
RL Submitted (JUL-2018) to the EMBL/GenBank/DDBJ databases.
RN [5] {ECO:0000313|Proteomes:UP000286681, ECO:0000313|Proteomes:UP000286696}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SK-NIH.Env10_0317 {ECO:0000313|EMBL:RSV04074.1,
RC ECO:0000313|Proteomes:UP000286681}, SK-NIH.Env11_0417
RC {ECO:0000313|EMBL:RSU81967.1, ECO:0000313|Proteomes:UP000287165},
RC SK-NIH.Env12_0417 {ECO:0000313|EMBL:RSU95535.1,
RC ECO:0000313|Proteomes:UP000288342}, SK-NIH.Env15_0417
RC {ECO:0000313|EMBL:RSU80892.1, ECO:0000313|Proteomes:UP000288648},
RC SK-NIH.Env1_1016 {ECO:0000313|EMBL:RSV65225.1,
RC ECO:0000313|Proteomes:UP000288283}, SK-NIH.Env5_1116
RC {ECO:0000313|EMBL:RSV61923.1, ECO:0000313|Proteomes:UP000287812},
RC SK-NIH.Env7_1116 {ECO:0000313|EMBL:RSX15945.1,
RC ECO:0000313|Proteomes:UP000288130}, SK-NIH.Env9_0217
RC {ECO:0000313|EMBL:RSU88415.1, ECO:0000313|Proteomes:UP000287377},
RC SK-NIH.Pt10_0210 {ECO:0000313|EMBL:RSV10109.1,
RC ECO:0000313|Proteomes:UP000288286}, SK-NIH.Pt11_0411
RC {ECO:0000313|EMBL:RSW93606.1, ECO:0000313|Proteomes:UP000288535},
RC SK-NIH.Pt12_0112 {ECO:0000313|EMBL:RSV54064.1,
RC ECO:0000313|Proteomes:UP000286696}, SK-NIH.Pt14_0612
RC {ECO:0000313|EMBL:RSV36515.1, ECO:0000313|Proteomes:UP000287457},
RC SK-NIH.Pt16_1112 {ECO:0000313|EMBL:RSV44063.1,
RC ECO:0000313|Proteomes:UP000287806}, SK-NIH.Pt7_0906
RC {ECO:0000313|EMBL:RSV25232.1, ECO:0000313|Proteomes:UP000288528},
RC SK-NIH.Pt8_0208 {ECO:0000313|EMBL:RSV29254.1,
RC ECO:0000313|Proteomes:UP000287886}, SK-NIH.Pt9_0208
RC {ECO:0000313|EMBL:RSV09704.1, ECO:0000313|Proteomes:UP000287793}, and
RC SK-NY1_0417 {ECO:0000313|EMBL:RSU97901.1,
RC ECO:0000313|Proteomes:UP000288253};
RA Johnson R.C., Deming C., Conlan S., Zellmer C.J., Michelin A.V.,
RA Lee-Lin S., Thomas P.J., Park M., Weingarten R.A., Less J., Dekker J.P.,
RA Frank K.M., Musser K.A., Mcquiston J.R., Henderson D.K., Lau A.F.,
RA Palmore T.N., Segre J.A.;
RT "Genomic and Epidemiologic Investigation of an Indolent Hospital
RT Outbreak.";
RL Submitted (JUL-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a (3S)-3-hydroxyacyl-CoA + NAD(+) = a 3-oxoacyl-CoA + H(+) +
CC NADH; Xref=Rhea:RHEA:22432, ChEBI:CHEBI:15378, ChEBI:CHEBI:57318,
CC ChEBI:CHEBI:57540, ChEBI:CHEBI:57945, ChEBI:CHEBI:90726; EC=1.1.1.35;
CC Evidence={ECO:0000256|ARBA:ARBA00023693};
CC -!- PATHWAY: Lipid metabolism; fatty acid beta-oxidation.
CC {ECO:0000256|ARBA:ARBA00005005}.
CC -!- SIMILARITY: Belongs to the enoyl-CoA hydratase/isomerase family.
CC {ECO:0000256|RuleBase:RU003707}.
CC -!- SIMILARITY: In the N-terminal section; belongs to the enoyl-CoA
CC hydratase/isomerase family. {ECO:0000256|ARBA:ARBA00008750}.
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DR EMBL; CP018820; APR52820.1; -; Genomic_DNA.
DR EMBL; QLJD01000006; RSU19329.1; -; Genomic_DNA.
DR EMBL; QLJF01000003; RSU28349.1; -; Genomic_DNA.
DR EMBL; QLJC01000002; RSU31330.1; -; Genomic_DNA.
DR EMBL; QLJI01000002; RSU38162.1; -; Genomic_DNA.
DR EMBL; QLJE01000004; RSU40227.1; -; Genomic_DNA.
DR EMBL; QLJJ01000002; RSU44323.1; -; Genomic_DNA.
DR EMBL; QLJG01000003; RSU51988.1; -; Genomic_DNA.
DR EMBL; QQWM01000005; RSU80892.1; -; Genomic_DNA.
DR EMBL; QQWL01000004; RSU81967.1; -; Genomic_DNA.
DR EMBL; QQWQ01000005; RSU88415.1; -; Genomic_DNA.
DR EMBL; QQWN01000007; RSU95535.1; -; Genomic_DNA.
DR EMBL; QQWP01000003; RSU97901.1; -; Genomic_DNA.
DR EMBL; QQWO01000006; RSV04074.1; -; Genomic_DNA.
DR EMBL; QQWS01000002; RSV09704.1; -; Genomic_DNA.
DR EMBL; QQWR01000004; RSV10109.1; -; Genomic_DNA.
DR EMBL; QQWU01000004; RSV25232.1; -; Genomic_DNA.
DR EMBL; QQWT01000004; RSV29254.1; -; Genomic_DNA.
DR EMBL; QQXA01000005; RSV36515.1; -; Genomic_DNA.
DR EMBL; QQXB01000012; RSV44063.1; -; Genomic_DNA.
DR EMBL; QQXD01000019; RSV54064.1; -; Genomic_DNA.
DR EMBL; QQXE01000001; RSV61923.1; -; Genomic_DNA.
DR EMBL; QQXG01000003; RSV65225.1; -; Genomic_DNA.
DR EMBL; QQXC01000013; RSW93606.1; -; Genomic_DNA.
DR EMBL; QQXR01000008; RSX06757.1; -; Genomic_DNA.
DR EMBL; QQXQ01000001; RSX10900.1; -; Genomic_DNA.
DR EMBL; QQXF01000002; RSX15945.1; -; Genomic_DNA.
DR EMBL; QQXS01000013; RSX19977.1; -; Genomic_DNA.
DR EMBL; QQXV01000001; RSX23379.1; -; Genomic_DNA.
DR EMBL; QQXU01000008; RSX27978.1; -; Genomic_DNA.
DR EMBL; QQXT01000003; RSX29061.1; -; Genomic_DNA.
DR EMBL; QQXW01000009; RSX37160.1; -; Genomic_DNA.
DR EMBL; QQXX01000003; RSX43589.1; -; Genomic_DNA.
DR EMBL; QQXY01000006; RSX45784.1; -; Genomic_DNA.
DR EMBL; QQXZ01000016; RSX63780.1; -; Genomic_DNA.
DR EMBL; QQYA01000003; RSX64112.1; -; Genomic_DNA.
DR EMBL; QQYD01000003; RSX67312.1; -; Genomic_DNA.
DR EMBL; QQYC01000008; RSX72311.1; -; Genomic_DNA.
DR EMBL; QQYB01000003; RSX80838.1; -; Genomic_DNA.
DR EMBL; QQYH01000007; RSX83144.1; -; Genomic_DNA.
DR EMBL; QQYF01000002; RSX91072.1; -; Genomic_DNA.
DR EMBL; QQYE01000007; RSX94975.1; -; Genomic_DNA.
DR EMBL; QQYG01000002; RSX95666.1; -; Genomic_DNA.
DR EMBL; QQYJ01000003; RSY02420.1; -; Genomic_DNA.
DR EMBL; QQYI01000002; RSY09705.1; -; Genomic_DNA.
DR EMBL; QQYN01000002; RSY14881.1; -; Genomic_DNA.
DR EMBL; QQYK01000003; RSY15141.1; -; Genomic_DNA.
DR EMBL; QQYL01000003; RSY22787.1; -; Genomic_DNA.
DR EMBL; QQYO01000006; RSY23781.1; -; Genomic_DNA.
DR EMBL; QQYM01000004; RSY29548.1; -; Genomic_DNA.
DR EMBL; QQYS01000003; RSY35380.1; -; Genomic_DNA.
DR EMBL; QQYQ01000004; RSY40087.1; -; Genomic_DNA.
DR EMBL; QQYR01000005; RSY45157.1; -; Genomic_DNA.
DR EMBL; QQYP01000002; RSY49290.1; -; Genomic_DNA.
DR EMBL; QQYU01000008; RSY52694.1; -; Genomic_DNA.
DR EMBL; QQYV01000007; RSY55073.1; -; Genomic_DNA.
DR EMBL; QQYW01000007; RSY60714.1; -; Genomic_DNA.
DR EMBL; QQYT01000004; RSY68503.1; -; Genomic_DNA.
DR EMBL; QQYX01000002; RSY73730.1; -; Genomic_DNA.
DR EMBL; QQYY01000002; RSY74126.1; -; Genomic_DNA.
DR EMBL; QQZB01000001; RSY86249.1; -; Genomic_DNA.
DR EMBL; QQZA01000002; RSY89016.1; -; Genomic_DNA.
DR EMBL; QQZD01000018; RSY90898.1; -; Genomic_DNA.
DR EMBL; QQZG01000010; RSY97368.1; -; Genomic_DNA.
DR EMBL; QQZE01000004; RSZ01939.1; -; Genomic_DNA.
DR EMBL; QQZF01000008; RSZ09286.1; -; Genomic_DNA.
DR EMBL; QQZC01000003; RSZ11690.1; -; Genomic_DNA.
DR EMBL; QQZH01000006; RSZ13681.1; -; Genomic_DNA.
DR EMBL; QQZI01000004; RSZ20732.1; -; Genomic_DNA.
DR RefSeq; WP_075151558.1; NZ_QQZI01000004.1.
DR AlphaFoldDB; A0A1L6JBD7; -.
DR STRING; 93064.BRX40_10645; -.
DR GeneID; 44133019; -.
DR KEGG; skr:BRX40_10645; -.
DR OrthoDB; 9771883at2; -.
DR UniPathway; UPA00659; -.
DR Proteomes; UP000185161; Chromosome.
DR Proteomes; UP000286681; Unassembled WGS sequence.
DR Proteomes; UP000286696; Unassembled WGS sequence.
DR Proteomes; UP000286706; Unassembled WGS sequence.
DR Proteomes; UP000286739; Unassembled WGS sequence.
DR Proteomes; UP000286744; Unassembled WGS sequence.
DR Proteomes; UP000286760; Unassembled WGS sequence.
DR Proteomes; UP000286788; Unassembled WGS sequence.
DR Proteomes; UP000286792; Unassembled WGS sequence.
DR Proteomes; UP000286795; Unassembled WGS sequence.
DR Proteomes; UP000286970; Unassembled WGS sequence.
DR Proteomes; UP000287001; Unassembled WGS sequence.
DR Proteomes; UP000287015; Unassembled WGS sequence.
DR Proteomes; UP000287020; Unassembled WGS sequence.
DR Proteomes; UP000287028; Unassembled WGS sequence.
DR Proteomes; UP000287038; Unassembled WGS sequence.
DR Proteomes; UP000287073; Unassembled WGS sequence.
DR Proteomes; UP000287083; Unassembled WGS sequence.
DR Proteomes; UP000287090; Unassembled WGS sequence.
DR Proteomes; UP000287165; Unassembled WGS sequence.
DR Proteomes; UP000287229; Unassembled WGS sequence.
DR Proteomes; UP000287236; Unassembled WGS sequence.
DR Proteomes; UP000287257; Unassembled WGS sequence.
DR Proteomes; UP000287271; Unassembled WGS sequence.
DR Proteomes; UP000287307; Unassembled WGS sequence.
DR Proteomes; UP000287315; Unassembled WGS sequence.
DR Proteomes; UP000287340; Unassembled WGS sequence.
DR Proteomes; UP000287347; Unassembled WGS sequence.
DR Proteomes; UP000287360; Unassembled WGS sequence.
DR Proteomes; UP000287363; Unassembled WGS sequence.
DR Proteomes; UP000287377; Unassembled WGS sequence.
DR Proteomes; UP000287414; Unassembled WGS sequence.
DR Proteomes; UP000287417; Unassembled WGS sequence.
DR Proteomes; UP000287457; Unassembled WGS sequence.
DR Proteomes; UP000287482; Unassembled WGS sequence.
DR Proteomes; UP000287513; Unassembled WGS sequence.
DR Proteomes; UP000287541; Unassembled WGS sequence.
DR Proteomes; UP000287577; Unassembled WGS sequence.
DR Proteomes; UP000287793; Unassembled WGS sequence.
DR Proteomes; UP000287799; Unassembled WGS sequence.
DR Proteomes; UP000287806; Unassembled WGS sequence.
DR Proteomes; UP000287812; Unassembled WGS sequence.
DR Proteomes; UP000287844; Unassembled WGS sequence.
DR Proteomes; UP000287886; Unassembled WGS sequence.
DR Proteomes; UP000287968; Unassembled WGS sequence.
DR Proteomes; UP000287976; Unassembled WGS sequence.
DR Proteomes; UP000288007; Unassembled WGS sequence.
DR Proteomes; UP000288050; Unassembled WGS sequence.
DR Proteomes; UP000288130; Unassembled WGS sequence.
DR Proteomes; UP000288181; Unassembled WGS sequence.
DR Proteomes; UP000288198; Unassembled WGS sequence.
DR Proteomes; UP000288203; Unassembled WGS sequence.
DR Proteomes; UP000288207; Unassembled WGS sequence.
DR Proteomes; UP000288230; Unassembled WGS sequence.
DR Proteomes; UP000288253; Unassembled WGS sequence.
DR Proteomes; UP000288258; Unassembled WGS sequence.
DR Proteomes; UP000288269; Unassembled WGS sequence.
DR Proteomes; UP000288283; Unassembled WGS sequence.
DR Proteomes; UP000288286; Unassembled WGS sequence.
DR Proteomes; UP000288342; Unassembled WGS sequence.
DR Proteomes; UP000288435; Unassembled WGS sequence.
DR Proteomes; UP000288516; Unassembled WGS sequence.
DR Proteomes; UP000288528; Unassembled WGS sequence.
DR Proteomes; UP000288535; Unassembled WGS sequence.
DR Proteomes; UP000288569; Unassembled WGS sequence.
DR Proteomes; UP000288581; Unassembled WGS sequence.
DR Proteomes; UP000288630; Unassembled WGS sequence.
DR Proteomes; UP000288648; Unassembled WGS sequence.
DR Proteomes; UP000288649; Unassembled WGS sequence.
DR GO; GO:0005777; C:peroxisome; IEA:UniProtKB-SubCell.
DR GO; GO:0003857; F:3-hydroxyacyl-CoA dehydrogenase activity; IEA:UniProtKB-EC.
DR GO; GO:0070403; F:NAD+ binding; IEA:InterPro.
DR GO; GO:0006635; P:fatty acid beta-oxidation; IEA:UniProtKB-UniPathway.
DR CDD; cd06558; crotonase-like; 1.
DR Gene3D; 1.10.1040.50; -; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR006176; 3-OHacyl-CoA_DH_NAD-bd.
DR InterPro; IPR006108; 3HC_DH_C.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR029045; ClpP/crotonase-like_dom_sf.
DR InterPro; IPR018376; Enoyl-CoA_hyd/isom_CS.
DR InterPro; IPR001753; Enoyl-CoA_hydra/iso.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR23309; 3-HYDROXYACYL-COA DEHYROGENASE; 1.
DR PANTHER; PTHR23309:SF9; PEROXISOMAL BIFUNCTIONAL ENZYME; 1.
DR Pfam; PF00725; 3HCDH; 2.
DR Pfam; PF02737; 3HCDH_N; 1.
DR Pfam; PF00378; ECH_1; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 2.
DR SUPFAM; SSF52096; ClpP/crotonase; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS00166; ENOYL_COA_HYDRATASE; 1.
PE 3: Inferred from homology;
KW Fatty acid metabolism {ECO:0000256|ARBA:ARBA00022832};
KW Lipid degradation {ECO:0000256|ARBA:ARBA00022963};
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00022832};
KW NAD {ECO:0000256|ARBA:ARBA00023027};
KW Peroxisome {ECO:0000256|ARBA:ARBA00023140};
KW Reference proteome {ECO:0000313|Proteomes:UP000185161}.
FT DOMAIN 294..469
FT /note="3-hydroxyacyl-CoA dehydrogenase NAD binding"
FT /evidence="ECO:0000259|Pfam:PF02737"
FT DOMAIN 474..558
FT /note="3-hydroxyacyl-CoA dehydrogenase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF00725"
FT DOMAIN 593..654
FT /note="3-hydroxyacyl-CoA dehydrogenase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF00725"
SQ SEQUENCE 676 AA; 72775 MW; 5645E3F4CBD2BDD4 CRC64;
MTGPITTERQ GDILVITSNN PPVNALGAAV RQGLDAAIKE LAGDDSLKAA VIRCDGRTFF
AGADITEFGK PMQEPSLPVL VDLIEASEKP VVAAVHGTAL GGGCEVALAC HYRIAVPSAK
FGLPEVKLGI LPGAGGTQRL PRVAGVEFAL ELATKGDPVS ASAAKDAGLV DRLAGEDSLT
ADAIAYADEI AAARPLPRTS EKPVTVEAGV FEAFRKTNAK RFRNMDAPAE IIAVIEETAG
KPYAEGVQRE RMGFMKLIMG AQSAALRHIF FAERKAAKID DVPEDTKLRP IKRVGVIGAG
TMGGGISMNF LSAGIPVTIA EMQQEALDRG TGTIRKNYEA TAAKGRMTAE QVEGAMGLLK
PTLDLNDLAE CDLIIEAVYE NMDVKKDIFG KLDKIAKPGA ILASNTSYLS IDEIASATGR
PGDVVGMHFF SPANIMKLLE VVRGAKTDKD VLATVMDLAK KIKKVAVVAG VCYGFIGNRM
LIPRQMEAMK LLHEGATPMQ VDKVHVEFGM PMGPFQMSDL AGVDIGWHRD PTRIENIRDA
LAAENRWGQK TKAGFYDYDD KRNPSPSPRV AEIIEEFRTK TGTPQHEVTD EEIMERTFYT
MVNEGAKILE EGMAQRASDI DVVWIYGYGW PPYRGGPMFW ADQVGLKTIV AGLEKHGFEI
SKLLRDKAES GGKFNG
//
