ID A0A1L6JE60_9SPHN Unreviewed; 149 AA.
AC A0A1L6JE60;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE RecName: Full=Deoxyuridine 5'-triphosphate nucleotidohydrolase {ECO:0000256|HAMAP-Rule:MF_00116};
DE Short=dUTPase {ECO:0000256|HAMAP-Rule:MF_00116};
DE EC=3.6.1.23 {ECO:0000256|HAMAP-Rule:MF_00116};
DE AltName: Full=dUTP pyrophosphatase {ECO:0000256|HAMAP-Rule:MF_00116};
GN Name=dut {ECO:0000256|HAMAP-Rule:MF_00116};
GN ORFNames=BDW16_3580 {ECO:0000313|EMBL:PJI90251.1}, BRX38_14020
GN {ECO:0000313|EMBL:RSU39927.1}, BRX39_09315
GN {ECO:0000313|EMBL:RSU34959.1}, BRX40_18725
GN {ECO:0000313|EMBL:APR54178.1}, CA221_01800
GN {ECO:0000313|EMBL:RSU53543.1}, CA222_12470
GN {ECO:0000313|EMBL:RSU25592.1}, CA223_02765
GN {ECO:0000313|EMBL:RSU43763.1}, CA224_15460
GN {ECO:0000313|EMBL:RSU18814.1}, CA225_14525
GN {ECO:0000313|EMBL:RSU25674.1}, CA226_11805
GN {ECO:0000313|EMBL:RSV63014.1}, CA227_18955
GN {ECO:0000313|EMBL:RSX08409.1}, CA228_13555
GN {ECO:0000313|EMBL:RSV56225.1}, CA229_05520
GN {ECO:0000313|EMBL:RSV59246.1}, CA230_03000
GN {ECO:0000313|EMBL:RSX01521.1}, CA231_09325
GN {ECO:0000313|EMBL:RSV47534.1}, CA232_12700
GN {ECO:0000313|EMBL:RSV36118.1}, CA238_06455
GN {ECO:0000313|EMBL:RSV26134.1}, CA239_14830
GN {ECO:0000313|EMBL:RSV26828.1}, CA240_16750
GN {ECO:0000313|EMBL:RSV03866.1}, CA242_13815
GN {ECO:0000313|EMBL:RSV07214.1}, CA253_11565
GN {ECO:0000313|EMBL:RSU87713.1}, CA256_11960
GN {ECO:0000313|EMBL:RSU94293.1}, CA257_10725
GN {ECO:0000313|EMBL:RSV03664.1}, DAH52_02980
GN {ECO:0000313|EMBL:RSU97751.1}, DAH53_13655
GN {ECO:0000313|EMBL:RSU79814.1}, DAH54_11140
GN {ECO:0000313|EMBL:RSU80635.1}, DAH55_08040
GN {ECO:0000313|EMBL:RSU69915.1}, DAH56_07470
GN {ECO:0000313|EMBL:RSU61270.1}, DAH57_06010
GN {ECO:0000313|EMBL:RSZ21235.1}, DAH58_14040
GN {ECO:0000313|EMBL:RSZ12689.1}, DAH59_08765
GN {ECO:0000313|EMBL:RSY99717.1}, DAH60_08910
GN {ECO:0000313|EMBL:RSZ12428.1}, DAH61_12335
GN {ECO:0000313|EMBL:RSY98472.1}, DAH62_15270
GN {ECO:0000313|EMBL:RSY93550.1}, DAH63_13400
GN {ECO:0000313|EMBL:RSZ07931.1}, DAH64_13910
GN {ECO:0000313|EMBL:RSY81403.1}, DAH65_17350
GN {ECO:0000313|EMBL:RSY82220.1}, DAH66_07825
GN {ECO:0000313|EMBL:RSY87527.1}, DAH67_07685
GN {ECO:0000313|EMBL:RSY73323.1}, DAH68_13820
GN {ECO:0000313|EMBL:RSY68735.1}, DAH69_12600
GN {ECO:0000313|EMBL:RSY61032.1}, DAH70_05955
GN {ECO:0000313|EMBL:RSY60399.1}, DAH71_15315
GN {ECO:0000313|EMBL:RSY52553.1}, DAH72_07515
GN {ECO:0000313|EMBL:RSY71194.1}, DAH73_10750
GN {ECO:0000313|EMBL:RSY34455.1}, DAH74_07670
GN {ECO:0000313|EMBL:RSY46070.1}, DAH75_03865
GN {ECO:0000313|EMBL:RSY41704.1}, DAH76_14345
GN {ECO:0000313|EMBL:RSY41389.1}, DAH77_07650
GN {ECO:0000313|EMBL:RSY26330.1}, DAH78_16070
GN {ECO:0000313|EMBL:RSY10203.1}, DAH79_13085
GN {ECO:0000313|EMBL:RSY27603.1}, DAH80_14285
GN {ECO:0000313|EMBL:RSY19022.1}, DAH81_13460
GN {ECO:0000313|EMBL:RSY11690.1}, DAH82_14240
GN {ECO:0000313|EMBL:RSY00296.1}, DAH83_10660
GN {ECO:0000313|EMBL:RSY06234.1}, DAH84_10245
GN {ECO:0000313|EMBL:RSX82298.1}, DAH85_14935
GN {ECO:0000313|EMBL:RSX89891.1}, DAH86_10985
GN {ECO:0000313|EMBL:RSX87708.1}, DAH87_15015
GN {ECO:0000313|EMBL:RSX94056.1}, DAH88_12395
GN {ECO:0000313|EMBL:RSX64017.1}, DAH89_12565
GN {ECO:0000313|EMBL:RSX72676.1}, DAH90_11975
GN {ECO:0000313|EMBL:RSX77941.1}, DAH91_09130
GN {ECO:0000313|EMBL:RSX62778.1}, DAH92_13120
GN {ECO:0000313|EMBL:RSX67678.1}, DAH93_12135
GN {ECO:0000313|EMBL:RSX45117.1}, DAH94_12245
GN {ECO:0000313|EMBL:RSX42022.1}, DAH95_06145
GN {ECO:0000313|EMBL:RSX38663.1}, DAH96_13300
GN {ECO:0000313|EMBL:RSX18499.1}, DAH97_16340
GN {ECO:0000313|EMBL:RSX27366.1}, DAH98_13260
GN {ECO:0000313|EMBL:RSX26499.1}, DAH99_14725
GN {ECO:0000313|EMBL:RSX21385.1}, DAI00_10855
GN {ECO:0000313|EMBL:RSX09116.1}, DAI01_06105
GN {ECO:0000313|EMBL:RSX08712.1};
OS Sphingomonas koreensis.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
OC Sphingomonadaceae; Sphingomonas.
OX NCBI_TaxID=93064 {ECO:0000313|EMBL:APR54178.1, ECO:0000313|Proteomes:UP000185161};
RN [1] {ECO:0000313|EMBL:APR54178.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=ABOJV {ECO:0000313|EMBL:APR54178.1};
RA Conlan S., Thomas P.J., Mullikin J., Palmore T.N., Frank K.M., Segre J.A.;
RT "Whole genome sequencing of Sphingomonas koreensis.";
RL Submitted (DEC-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000185161}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ABOJV {ECO:0000313|Proteomes:UP000185161};
RA Conlan S., Thomas P.J., Mullikin J., Palmore T.N., Frank K.M., Segre J.A.;
RT "Whole genome sequencing of Sphingomonas sp. ABOJV.";
RL Submitted (DEC-2016) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Proteomes:UP000228629}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JSS26 {ECO:0000313|Proteomes:UP000228629};
RA Blow M.;
RT "Pac Bio to generate improved reference genome sequences for organisms with
RT transposon mutant libraries (support for FEBA project).";
RL Submitted (NOV-2017) to the EMBL/GenBank/DDBJ databases.
RN [4] {ECO:0000313|EMBL:PJI90251.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=JSS26 {ECO:0000313|EMBL:PJI90251.1};
RA Han C.G.;
RL Submitted (NOV-2017) to the EMBL/GenBank/DDBJ databases.
RN [5] {ECO:0000313|EMBL:PJI90251.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=JSS26 {ECO:0000313|EMBL:PJI90251.1};
RX PubMed=29769716; DOI=10.1038/s41586-018-0124-0;
RA Price M.N., Wetmore K.M., Waters R.J., Callaghan M., Ray J., Liu H.,
RA Kuehl J.V., Melnyk R.A., Lamson J.S., Suh Y., Carlson H.K., Esquivel Z.,
RA Sadeeshkumar H., Chakraborty R., Zane G.M., Rubin B.E., Wall J.D.,
RA Visel A., Bristow J., Blow M.J., Arkin A.P., Deutschbauer A.M.;
RT "Mutant phenotypes for thousands of bacterial genes of unknown function.";
RL Nature 557:503-509(2018).
RN [6] {ECO:0000313|Proteomes:UP000286970, ECO:0000313|Proteomes:UP000287271}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SK-NIH.Env2_1116 {ECO:0000313|EMBL:RSU25592.1,
RC ECO:0000313|Proteomes:UP000286970}, SK-NIH.Env3_1116
RC {ECO:0000313|EMBL:RSU43763.1, ECO:0000313|Proteomes:UP000287271},
RC SK-NIH.Env4_1116 {ECO:0000313|EMBL:RSU18814.1,
RC ECO:0000313|Proteomes:UP000287347}, SK-NIH.Env8_1116
RC {ECO:0000313|EMBL:RSU25674.1, ECO:0000313|Proteomes:UP000287976},
RC SK-NIH.Pt2_0716 {ECO:0000313|EMBL:RSU39927.1,
RC ECO:0000313|Proteomes:UP000287307}, SK-NIH.Pt4_0816
RC {ECO:0000313|EMBL:RSU34959.1, ECO:0000313|Proteomes:UP000287414}, and
RC SK-NIH.Pt6_1016 {ECO:0000313|EMBL:RSU53543.1,
RC ECO:0000313|Proteomes:UP000287315};
RA Johnson R.C., Deming C., Conlan S., Zellmer C., Michelin A., Lee-Lin S.-Q.,
RA Thomas P.J., Park M., Weingarten R.A., Less J., Dekker J.P., Frank K.M.,
RA Musser K.A., Mcquiston J.R., Henderson D.K., Lau A.F., Palmore T.N.,
RA Segre J.A.;
RT "Genomic and Epidemiologic Investigation to Identify Sphingomonas koreensis
RT Point Sources in an Indolent Hospital Outbreak.";
RL Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases.
RN [7] {ECO:0000313|Proteomes:UP000286681, ECO:0000313|Proteomes:UP000286696}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KCTC 2882 {ECO:0000313|EMBL:RSU69915.1,
RC ECO:0000313|Proteomes:UP000286710}, KCTC 2883
RC {ECO:0000313|EMBL:RSU61270.1, ECO:0000313|Proteomes:UP000286956},
RC SK-CDC1_0717 {ECO:0000313|EMBL:RSY87527.1,
RC ECO:0000313|Proteomes:UP000287746}, SK-NIH.Env10_0317
RC {ECO:0000313|EMBL:RSV03664.1, ECO:0000313|Proteomes:UP000286681},
RC SK-NIH.Env11_0417 {ECO:0000313|EMBL:RSU80635.1,
RC ECO:0000313|Proteomes:UP000287165}, SK-NIH.Env12_0417
RC {ECO:0000313|EMBL:RSU97751.1, ECO:0000313|Proteomes:UP000288342},
RC SK-NIH.Env15_0417 {ECO:0000313|EMBL:RSU79814.1,
RC ECO:0000313|Proteomes:UP000288648}, SK-NIH.Env1_1016
RC {ECO:0000313|EMBL:RSV63014.1, ECO:0000313|Proteomes:UP000288283},
RC SK-NIH.Env5_1116 {ECO:0000313|EMBL:RSV56225.1,
RC ECO:0000313|Proteomes:UP000287812}, SK-NIH.Env7_1116
RC {ECO:0000313|EMBL:RSX08409.1, ECO:0000313|Proteomes:UP000288130},
RC SK-NIH.Env9_0217 {ECO:0000313|EMBL:RSU87713.1,
RC ECO:0000313|Proteomes:UP000287377}, SK-NIH.Pt10_0210
RC {ECO:0000313|EMBL:RSV07214.1, ECO:0000313|Proteomes:UP000288286},
RC SK-NIH.Pt11_0411 {ECO:0000313|EMBL:RSX01521.1,
RC ECO:0000313|Proteomes:UP000288535}, SK-NIH.Pt12_0112
RC {ECO:0000313|EMBL:RSV59246.1, ECO:0000313|Proteomes:UP000286696},
RC SK-NIH.Pt14_0612 {ECO:0000313|EMBL:RSV36118.1,
RC ECO:0000313|Proteomes:UP000287457}, SK-NIH.Pt16_1112
RC {ECO:0000313|EMBL:RSV47534.1, ECO:0000313|Proteomes:UP000287806},
RC SK-NIH.Pt7_0906 {ECO:0000313|EMBL:RSV26134.1,
RC ECO:0000313|Proteomes:UP000288528}, SK-NIH.Pt8_0208
RC {ECO:0000313|EMBL:RSV26828.1, ECO:0000313|Proteomes:UP000287886},
RC SK-NIH.Pt9_0208 {ECO:0000313|EMBL:RSV03866.1,
RC ECO:0000313|Proteomes:UP000287793}, and SK-NY1_0417
RC {ECO:0000313|EMBL:RSU94293.1, ECO:0000313|Proteomes:UP000288253};
RA Johnson R.C., Deming C., Conlan S., Zellmer C.J., Michelin A.V.,
RA Lee-Lin S., Thomas P.J., Park M., Weingarten R.A., Less J., Dekker J.P.,
RA Frank K.M., Musser K.A., Mcquiston J.R., Henderson D.K., Lau A.F.,
RA Palmore T.N., Segre J.A.;
RT "Genomic and Epidemiologic Investigation of an Indolent Hospital
RT Outbreak.";
RL Submitted (JUL-2018) to the EMBL/GenBank/DDBJ databases.
RN [8] {ECO:0000313|Proteomes:UP000286706, ECO:0000313|Proteomes:UP000286739}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SK-NIH.Env13_0417 {ECO:0000313|EMBL:RSZ12689.1,
RC ECO:0000313|Proteomes:UP000287513}, SK-NIH.Env14_0417
RC {ECO:0000313|EMBL:RSY99717.1, ECO:0000313|Proteomes:UP000288569},
RC SK-NIH.Env16_0517 {ECO:0000313|EMBL:RSZ12428.1,
RC ECO:0000313|Proteomes:UP000287015}, SK-NIH.Env17_0517
RC {ECO:0000313|EMBL:RSZ21235.1, ECO:0000313|Proteomes:UP000287799},
RC SK-NIH.Env18_0517 {ECO:0000313|EMBL:RSY98472.1,
RC ECO:0000313|Proteomes:UP000288230}, SK-NIH.Env19_0617
RC {ECO:0000313|EMBL:RSY81403.1, ECO:0000313|Proteomes:UP000288258},
RC SK-NIH.Env20_0617 {ECO:0000313|EMBL:RSY82220.1,
RC ECO:0000313|Proteomes:UP000287482}, SK-NIH.Env21_0617
RC {ECO:0000313|EMBL:RSY93550.1, ECO:0000313|Proteomes:UP000287363},
RC SK-NIH.Env22_0617 {ECO:0000313|EMBL:RSZ07931.1,
RC ECO:0000313|Proteomes:UP000287001}, SK-NIH.Env23_0717
RC {ECO:0000313|EMBL:RSY73323.1, ECO:0000313|Proteomes:UP000287360},
RC SK-NIH.Env24_0717 {ECO:0000313|EMBL:RSY68735.1,
RC ECO:0000313|Proteomes:UP000287229}, SK-NIH.Env25_0717
RC {ECO:0000313|EMBL:RSY61032.1, ECO:0000313|Proteomes:UP000288269},
RC SK-NIH.Env26_0717 {ECO:0000313|EMBL:RSY60399.1,
RC ECO:0000313|Proteomes:UP000287417}, SK-NIH.Env27_0717
RC {ECO:0000313|EMBL:RSY52553.1, ECO:0000313|Proteomes:UP000286788},
RC SK-NIH.Env28_0717 {ECO:0000313|EMBL:RSY71194.1,
RC ECO:0000313|Proteomes:UP000288630}, SK-NIH.Env29_0717
RC {ECO:0000313|EMBL:RSY34455.1, ECO:0000313|Proteomes:UP000287038},
RC SK-NIH.Env30_0717 {ECO:0000313|EMBL:RSY46070.1,
RC ECO:0000313|Proteomes:UP000288207}, SK-NIH.Env31_0717
RC {ECO:0000313|EMBL:RSY41704.1, ECO:0000313|Proteomes:UP000287340},
RC SK-NIH.Env32_0717 {ECO:0000313|EMBL:RSY41389.1,
RC ECO:0000313|Proteomes:UP000288007}, SK-NIH.Env33_0717
RC {ECO:0000313|EMBL:RSY26330.1, ECO:0000313|Proteomes:UP000287541},
RC SK-NIH.Env34_0717 {ECO:0000313|EMBL:RSY10203.1,
RC ECO:0000313|Proteomes:UP000288649}, SK-NIH.Env35_0717
RC {ECO:0000313|EMBL:RSY27603.1, ECO:0000313|Proteomes:UP000287968},
RC SK-NIH.Env36_0717 {ECO:0000313|EMBL:RSY00296.1,
RC ECO:0000313|Proteomes:UP000288516}, SK-NIH.Env37_0717
RC {ECO:0000313|EMBL:RSY19022.1, ECO:0000313|Proteomes:UP000287028},
RC SK-NIH.Env38_0817 {ECO:0000313|EMBL:RSY11690.1,
RC ECO:0000313|Proteomes:UP000287257}, SK-NIH.Env39_0817
RC {ECO:0000313|EMBL:RSY06234.1, ECO:0000313|Proteomes:UP000287073},
RC SK-NIH.Env40_0817 {ECO:0000313|EMBL:RSX82298.1,
RC ECO:0000313|Proteomes:UP000288050}, SK-NIH.Env41_0817
RC {ECO:0000313|EMBL:RSX89891.1, ECO:0000313|Proteomes:UP000286739},
RC SK-NIH.Env42_0817 {ECO:0000313|EMBL:RSX87708.1,
RC ECO:0000313|Proteomes:UP000288181}, SK-NIH.Env43_0817
RC {ECO:0000313|EMBL:RSX94056.1, ECO:0000313|Proteomes:UP000286795},
RC SK-NIH.Env44_0817 {ECO:0000313|EMBL:RSX64017.1,
RC ECO:0000313|Proteomes:UP000286792}, SK-NIH.Env45_1017
RC {ECO:0000313|EMBL:RSX72676.1, ECO:0000313|Proteomes:UP000286760},
RC SK-NIH.Env46_1017 {ECO:0000313|EMBL:RSX67678.1,
RC ECO:0000313|Proteomes:UP000287577}, SK-NIH.Env47_1017
RC {ECO:0000313|EMBL:RSX45117.1, ECO:0000313|Proteomes:UP000288581},
RC SK-NIH.Env48_1017 {ECO:0000313|EMBL:RSX77941.1,
RC ECO:0000313|Proteomes:UP000287090}, SK-NIH.Env49_1017
RC {ECO:0000313|EMBL:RSX62778.1, ECO:0000313|Proteomes:UP000286744},
RC SK-NIH.Env50_1017 {ECO:0000313|EMBL:RSX42022.1,
RC ECO:0000313|Proteomes:UP000288198}, SK-NIH.Env51_1017
RC {ECO:0000313|EMBL:RSX38663.1, ECO:0000313|Proteomes:UP000287844},
RC SK-NIH.Env52_1017 {ECO:0000313|EMBL:RSX18499.1,
RC ECO:0000313|Proteomes:UP000287083}, SK-NIH.Env53_1017
RC {ECO:0000313|EMBL:RSX27366.1, ECO:0000313|Proteomes:UP000288435},
RC SK-NIH.Env54_1217 {ECO:0000313|EMBL:RSX21385.1,
RC ECO:0000313|Proteomes:UP000288203}, SK-NIH.Env55_1217
RC {ECO:0000313|EMBL:RSX09116.1, ECO:0000313|Proteomes:UP000286706},
RC SK-NIH.Env56_1217 {ECO:0000313|EMBL:RSX08712.1,
RC ECO:0000313|Proteomes:UP000287020}, and SK-NIH.Env57_1217
RC {ECO:0000313|EMBL:RSX26499.1, ECO:0000313|Proteomes:UP000287236};
RA Johnson R.C., Deming C., Conlan S., Zellmer C.J., Michelin A.V.,
RA Lee-Lin S.-Q., Thomas P.J., Park M., Weingarten R.A., Less J., Dekker J.P.,
RA Frank K.M., Musser K.A., Mcquiston J.R., Henderson D.K., Lau A.F.,
RA Palmore T.N., Segre J.A.;
RT "Genomic and Epidemiologic Investigation of an Indolent Hospital
RT Outbreak.";
RL Submitted (JUL-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: This enzyme is involved in nucleotide metabolism: it produces
CC dUMP, the immediate precursor of thymidine nucleotides and it decreases
CC the intracellular concentration of dUTP so that uracil cannot be
CC incorporated into DNA. {ECO:0000256|HAMAP-Rule:MF_00116}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=dUTP + H2O = diphosphate + dUMP + H(+); Xref=Rhea:RHEA:10248,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:33019,
CC ChEBI:CHEBI:61555, ChEBI:CHEBI:246422; EC=3.6.1.23;
CC Evidence={ECO:0000256|ARBA:ARBA00000878, ECO:0000256|HAMAP-
CC Rule:MF_00116};
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|HAMAP-Rule:MF_00116};
CC -!- PATHWAY: Pyrimidine metabolism; dUMP biosynthesis; dUMP from dCTP (dUTP
CC route): step 2/2. {ECO:0000256|HAMAP-Rule:MF_00116}.
CC -!- SIMILARITY: Belongs to the dUTPase family.
CC {ECO:0000256|ARBA:ARBA00006581, ECO:0000256|HAMAP-Rule:MF_00116}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|HAMAP-Rule:MF_00116}.
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DR EMBL; CP018820; APR54178.1; -; Genomic_DNA.
DR EMBL; PGEN01000001; PJI90251.1; -; Genomic_DNA.
DR EMBL; QLJD01000008; RSU18814.1; -; Genomic_DNA.
DR EMBL; QLJF01000008; RSU25592.1; -; Genomic_DNA.
DR EMBL; QLJC01000011; RSU25674.1; -; Genomic_DNA.
DR EMBL; QLJI01000006; RSU34959.1; -; Genomic_DNA.
DR EMBL; QLJJ01000010; RSU39927.1; -; Genomic_DNA.
DR EMBL; QLJE01000001; RSU43763.1; -; Genomic_DNA.
DR EMBL; QLJG01000001; RSU53543.1; -; Genomic_DNA.
DR EMBL; QQWJ01000005; RSU61270.1; -; Genomic_DNA.
DR EMBL; QQWK01000005; RSU69915.1; -; Genomic_DNA.
DR EMBL; QQWM01000007; RSU79814.1; -; Genomic_DNA.
DR EMBL; QQWL01000006; RSU80635.1; -; Genomic_DNA.
DR EMBL; QQWQ01000007; RSU87713.1; -; Genomic_DNA.
DR EMBL; QQWP01000009; RSU94293.1; -; Genomic_DNA.
DR EMBL; QQWN01000002; RSU97751.1; -; Genomic_DNA.
DR EMBL; QQWO01000007; RSV03664.1; -; Genomic_DNA.
DR EMBL; QQWS01000010; RSV03866.1; -; Genomic_DNA.
DR EMBL; QQWR01000009; RSV07214.1; -; Genomic_DNA.
DR EMBL; QQWU01000003; RSV26134.1; -; Genomic_DNA.
DR EMBL; QQWT01000009; RSV26828.1; -; Genomic_DNA.
DR EMBL; QQXA01000007; RSV36118.1; -; Genomic_DNA.
DR EMBL; QQXB01000004; RSV47534.1; -; Genomic_DNA.
DR EMBL; QQXE01000009; RSV56225.1; -; Genomic_DNA.
DR EMBL; QQXD01000004; RSV59246.1; -; Genomic_DNA.
DR EMBL; QQXG01000007; RSV63014.1; -; Genomic_DNA.
DR EMBL; QQXC01000002; RSX01521.1; -; Genomic_DNA.
DR EMBL; QQXF01000024; RSX08409.1; -; Genomic_DNA.
DR EMBL; QQXQ01000003; RSX08712.1; -; Genomic_DNA.
DR EMBL; QQXR01000005; RSX09116.1; -; Genomic_DNA.
DR EMBL; QQXV01000006; RSX18499.1; -; Genomic_DNA.
DR EMBL; QQXS01000009; RSX21385.1; -; Genomic_DNA.
DR EMBL; QQXT01000008; RSX26499.1; -; Genomic_DNA.
DR EMBL; QQXU01000009; RSX27366.1; -; Genomic_DNA.
DR EMBL; QQXW01000003; RSX38663.1; -; Genomic_DNA.
DR EMBL; QQXX01000007; RSX42022.1; -; Genomic_DNA.
DR EMBL; QQXY01000007; RSX45117.1; -; Genomic_DNA.
DR EMBL; QQYA01000006; RSX62778.1; -; Genomic_DNA.
DR EMBL; QQYD01000008; RSX64017.1; -; Genomic_DNA.
DR EMBL; QQXZ01000007; RSX67678.1; -; Genomic_DNA.
DR EMBL; QQYC01000007; RSX72676.1; -; Genomic_DNA.
DR EMBL; QQYB01000009; RSX77941.1; -; Genomic_DNA.
DR EMBL; QQYH01000008; RSX82298.1; -; Genomic_DNA.
DR EMBL; QQYF01000007; RSX87708.1; -; Genomic_DNA.
DR EMBL; QQYG01000010; RSX89891.1; -; Genomic_DNA.
DR EMBL; QQYE01000009; RSX94056.1; -; Genomic_DNA.
DR EMBL; QQYJ01000009; RSY00296.1; -; Genomic_DNA.
DR EMBL; QQYI01000007; RSY06234.1; -; Genomic_DNA.
DR EMBL; QQYN01000011; RSY10203.1; -; Genomic_DNA.
DR EMBL; QQYK01000007; RSY11690.1; -; Genomic_DNA.
DR EMBL; QQYL01000009; RSY19022.1; -; Genomic_DNA.
DR EMBL; QQYO01000003; RSY26330.1; -; Genomic_DNA.
DR EMBL; QQYM01000007; RSY27603.1; -; Genomic_DNA.
DR EMBL; QQYS01000004; RSY34455.1; -; Genomic_DNA.
DR EMBL; QQYP01000008; RSY41389.1; -; Genomic_DNA.
DR EMBL; QQYQ01000002; RSY41704.1; -; Genomic_DNA.
DR EMBL; QQYR01000003; RSY46070.1; -; Genomic_DNA.
DR EMBL; QQYU01000009; RSY52553.1; -; Genomic_DNA.
DR EMBL; QQYV01000003; RSY60399.1; -; Genomic_DNA.
DR EMBL; QQYW01000006; RSY61032.1; -; Genomic_DNA.
DR EMBL; QQYX01000010; RSY68735.1; -; Genomic_DNA.
DR EMBL; QQYT01000003; RSY71194.1; -; Genomic_DNA.
DR EMBL; QQYY01000003; RSY73323.1; -; Genomic_DNA.
DR EMBL; QQZB01000008; RSY81403.1; -; Genomic_DNA.
DR EMBL; QQZA01000012; RSY82220.1; -; Genomic_DNA.
DR EMBL; QQYZ01000005; RSY87527.1; -; Genomic_DNA.
DR EMBL; QQZD01000009; RSY93550.1; -; Genomic_DNA.
DR EMBL; QQZE01000009; RSY98472.1; -; Genomic_DNA.
DR EMBL; QQZG01000006; RSY99717.1; -; Genomic_DNA.
DR EMBL; QQZC01000008; RSZ07931.1; -; Genomic_DNA.
DR EMBL; QQZF01000004; RSZ12428.1; -; Genomic_DNA.
DR EMBL; QQZH01000007; RSZ12689.1; -; Genomic_DNA.
DR EMBL; QQZI01000003; RSZ21235.1; -; Genomic_DNA.
DR RefSeq; WP_066574839.1; NZ_QQZI01000003.1.
DR STRING; 93064.BRX40_18725; -.
DR GeneID; 44134598; -.
DR KEGG; skr:BRX40_18725; -.
DR OrthoDB; 9809956at2; -.
DR UniPathway; UPA00610; UER00666.
DR Proteomes; UP000185161; Chromosome.
DR Proteomes; UP000228629; Unassembled WGS sequence.
DR Proteomes; UP000286681; Unassembled WGS sequence.
DR Proteomes; UP000286696; Unassembled WGS sequence.
DR Proteomes; UP000286706; Unassembled WGS sequence.
DR Proteomes; UP000286710; Unassembled WGS sequence.
DR Proteomes; UP000286739; Unassembled WGS sequence.
DR Proteomes; UP000286744; Unassembled WGS sequence.
DR Proteomes; UP000286760; Unassembled WGS sequence.
DR Proteomes; UP000286788; Unassembled WGS sequence.
DR Proteomes; UP000286792; Unassembled WGS sequence.
DR Proteomes; UP000286795; Unassembled WGS sequence.
DR Proteomes; UP000286956; Unassembled WGS sequence.
DR Proteomes; UP000286970; Unassembled WGS sequence.
DR Proteomes; UP000287001; Unassembled WGS sequence.
DR Proteomes; UP000287015; Unassembled WGS sequence.
DR Proteomes; UP000287020; Unassembled WGS sequence.
DR Proteomes; UP000287028; Unassembled WGS sequence.
DR Proteomes; UP000287038; Unassembled WGS sequence.
DR Proteomes; UP000287073; Unassembled WGS sequence.
DR Proteomes; UP000287083; Unassembled WGS sequence.
DR Proteomes; UP000287090; Unassembled WGS sequence.
DR Proteomes; UP000287165; Unassembled WGS sequence.
DR Proteomes; UP000287229; Unassembled WGS sequence.
DR Proteomes; UP000287236; Unassembled WGS sequence.
DR Proteomes; UP000287257; Unassembled WGS sequence.
DR Proteomes; UP000287271; Unassembled WGS sequence.
DR Proteomes; UP000287307; Unassembled WGS sequence.
DR Proteomes; UP000287315; Unassembled WGS sequence.
DR Proteomes; UP000287340; Unassembled WGS sequence.
DR Proteomes; UP000287347; Unassembled WGS sequence.
DR Proteomes; UP000287360; Unassembled WGS sequence.
DR Proteomes; UP000287363; Unassembled WGS sequence.
DR Proteomes; UP000287377; Unassembled WGS sequence.
DR Proteomes; UP000287414; Unassembled WGS sequence.
DR Proteomes; UP000287417; Unassembled WGS sequence.
DR Proteomes; UP000287457; Unassembled WGS sequence.
DR Proteomes; UP000287482; Unassembled WGS sequence.
DR Proteomes; UP000287513; Unassembled WGS sequence.
DR Proteomes; UP000287541; Unassembled WGS sequence.
DR Proteomes; UP000287577; Unassembled WGS sequence.
DR Proteomes; UP000287746; Unassembled WGS sequence.
DR Proteomes; UP000287793; Unassembled WGS sequence.
DR Proteomes; UP000287799; Unassembled WGS sequence.
DR Proteomes; UP000287806; Unassembled WGS sequence.
DR Proteomes; UP000287812; Unassembled WGS sequence.
DR Proteomes; UP000287844; Unassembled WGS sequence.
DR Proteomes; UP000287886; Unassembled WGS sequence.
DR Proteomes; UP000287968; Unassembled WGS sequence.
DR Proteomes; UP000287976; Unassembled WGS sequence.
DR Proteomes; UP000288007; Unassembled WGS sequence.
DR Proteomes; UP000288050; Unassembled WGS sequence.
DR Proteomes; UP000288130; Unassembled WGS sequence.
DR Proteomes; UP000288181; Unassembled WGS sequence.
DR Proteomes; UP000288198; Unassembled WGS sequence.
DR Proteomes; UP000288203; Unassembled WGS sequence.
DR Proteomes; UP000288207; Unassembled WGS sequence.
DR Proteomes; UP000288230; Unassembled WGS sequence.
DR Proteomes; UP000288253; Unassembled WGS sequence.
DR Proteomes; UP000288258; Unassembled WGS sequence.
DR Proteomes; UP000288269; Unassembled WGS sequence.
DR Proteomes; UP000288283; Unassembled WGS sequence.
DR Proteomes; UP000288286; Unassembled WGS sequence.
DR Proteomes; UP000288342; Unassembled WGS sequence.
DR Proteomes; UP000288435; Unassembled WGS sequence.
DR Proteomes; UP000288516; Unassembled WGS sequence.
DR Proteomes; UP000288528; Unassembled WGS sequence.
DR Proteomes; UP000288535; Unassembled WGS sequence.
DR Proteomes; UP000288569; Unassembled WGS sequence.
DR Proteomes; UP000288581; Unassembled WGS sequence.
DR Proteomes; UP000288630; Unassembled WGS sequence.
DR Proteomes; UP000288648; Unassembled WGS sequence.
DR Proteomes; UP000288649; Unassembled WGS sequence.
DR GO; GO:0004170; F:dUTP diphosphatase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0000287; F:magnesium ion binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006226; P:dUMP biosynthetic process; IEA:UniProtKB-UniPathway.
DR GO; GO:0046081; P:dUTP catabolic process; IEA:InterPro.
DR CDD; cd07557; trimeric_dUTPase; 1.
DR Gene3D; 2.70.40.10; -; 1.
DR HAMAP; MF_00116; dUTPase_bact; 1.
DR InterPro; IPR008181; dUTPase.
DR InterPro; IPR029054; dUTPase-like.
DR InterPro; IPR036157; dUTPase-like_sf.
DR InterPro; IPR033704; dUTPase_trimeric.
DR NCBIfam; TIGR00576; dut; 1.
DR PANTHER; PTHR11241; DEOXYURIDINE 5'-TRIPHOSPHATE NUCLEOTIDOHYDROLASE; 1.
DR PANTHER; PTHR11241:SF0; DEOXYURIDINE 5'-TRIPHOSPHATE NUCLEOTIDOHYDROLASE; 1.
DR Pfam; PF00692; dUTPase; 1.
DR SUPFAM; SSF51283; dUTPase-like; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|HAMAP-Rule:MF_00116};
KW Magnesium {ECO:0000256|HAMAP-Rule:MF_00116};
KW Metal-binding {ECO:0000256|HAMAP-Rule:MF_00116};
KW Nucleotide metabolism {ECO:0000256|ARBA:ARBA00023080, ECO:0000256|HAMAP-
KW Rule:MF_00116}; Reference proteome {ECO:0000313|Proteomes:UP000185161}.
FT DOMAIN 20..148
FT /note="dUTPase-like"
FT /evidence="ECO:0000259|Pfam:PF00692"
FT BINDING 69..71
FT /ligand="substrate"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_00116"
FT BINDING 82
FT /ligand="substrate"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_00116"
FT BINDING 86..88
FT /ligand="substrate"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_00116"
SQ SEQUENCE 149 AA; 15304 MW; D32364145684B19C CRC64;
MTAAPITIQL TRLPHGEGLP LPAYATAGAA GMDVVAAEDL ILAPGARHAV ATGFAIAIPE
GYEVQVRPRS GLALKHGITC LNTPGTIDSD YRGEVKVILA NLGGYPFTIT RGERIAQLVA
APVQRAVFAE VDALDDTARG AGGFGSTGR
//
