ID A0A1L6JFY6_9SPHN Unreviewed; 281 AA.
AC A0A1L6JFY6;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=Formyltetrahydrofolate deformylase {ECO:0000256|HAMAP-Rule:MF_01927};
DE EC=3.5.1.10 {ECO:0000256|HAMAP-Rule:MF_01927};
DE AltName: Full=Formyl-FH(4) hydrolase {ECO:0000256|HAMAP-Rule:MF_01927};
GN Name=purU {ECO:0000256|HAMAP-Rule:MF_01927,
GN ECO:0000313|EMBL:RSU23051.1};
GN ORFNames=BRX38_00470 {ECO:0000313|EMBL:RSU45027.1}, BRX39_01050
GN {ECO:0000313|EMBL:RSU39500.1}, BRX40_05525
GN {ECO:0000313|EMBL:APR54834.1}, CA221_07810
GN {ECO:0000313|EMBL:RSU51495.1}, CA222_01400
GN {ECO:0000313|EMBL:RSU30958.1}, CA223_06955
GN {ECO:0000313|EMBL:RSU41349.1}, CA224_05145
GN {ECO:0000313|EMBL:RSU23051.1}, CA225_00480
GN {ECO:0000313|EMBL:RSU32260.1}, CA226_20215
GN {ECO:0000313|EMBL:RSV58757.1}, CA227_05315
GN {ECO:0000313|EMBL:RSX14817.1}, CA228_02775
GN {ECO:0000313|EMBL:RSV61115.1}, CA229_01715
GN {ECO:0000313|EMBL:RSV60696.1}, CA230_01400
GN {ECO:0000313|EMBL:RSX03060.1}, CA231_02920
GN {ECO:0000313|EMBL:RSV49065.1}, CA232_03925
GN {ECO:0000313|EMBL:RSV38590.1}, CA238_01560
GN {ECO:0000313|EMBL:RSV28632.1}, CA239_01320
GN {ECO:0000313|EMBL:RSV31489.1}, CA240_02100
GN {ECO:0000313|EMBL:RSV11136.1}, CA242_01400
GN {ECO:0000313|EMBL:RSV13065.1}, CA253_03560
GN {ECO:0000313|EMBL:RSU90998.1}, CA256_01060
GN {ECO:0000313|EMBL:RSU99902.1}, CA257_00485
GN {ECO:0000313|EMBL:RSV08370.1}, DAH52_21625
GN {ECO:0000313|EMBL:RSU89531.1}, DAH53_01400
GN {ECO:0000313|EMBL:RSU85856.1}, DAH54_04070
GN {ECO:0000313|EMBL:RSU84751.1}, DAH55_13805
GN {ECO:0000313|EMBL:RSU67278.1}, DAH56_14390
GN {ECO:0000313|EMBL:RSU58913.1}, DAH57_01400
GN {ECO:0000313|EMBL:RSZ22381.1}, DAH58_01400
GN {ECO:0000313|EMBL:RSZ18253.1}, DAH59_02945
GN {ECO:0000313|EMBL:RSZ02468.1}, DAH60_01400
GN {ECO:0000313|EMBL:RSZ16178.1}, DAH61_05490
GN {ECO:0000313|EMBL:RSZ03651.1}, DAH62_02340
GN {ECO:0000313|EMBL:RSZ00628.1}, DAH63_03360
GN {ECO:0000313|EMBL:RSZ13575.1}, DAH64_04895
GN {ECO:0000313|EMBL:RSY84552.1}, DAH65_05440
GN {ECO:0000313|EMBL:RSY88489.1}, DAH67_01400
GN {ECO:0000313|EMBL:RSY76187.1}, DAH68_00485
GN {ECO:0000313|EMBL:RSY75467.1}, DAH69_01400
GN {ECO:0000313|EMBL:RSY64432.1}, DAH70_03565
GN {ECO:0000313|EMBL:RSY62998.1}, DAH71_07635
GN {ECO:0000313|EMBL:RSY54447.1}, DAH72_01400
GN {ECO:0000313|EMBL:RSY77316.1}, DAH73_01395
GN {ECO:0000313|EMBL:RSY38655.1}, DAH74_04775
GN {ECO:0000313|EMBL:RSY47406.1}, DAH75_11600
GN {ECO:0000313|EMBL:RSY39128.1}, DAH76_00485
GN {ECO:0000313|EMBL:RSY51860.1}, DAH77_02465
GN {ECO:0000313|EMBL:RSY28867.1}, DAH78_00485
GN {ECO:0000313|EMBL:RSY16117.1}, DAH79_01050
GN {ECO:0000313|EMBL:RSY32234.1}, DAH80_04065
GN {ECO:0000313|EMBL:RSY24424.1}, DAH81_01400
GN {ECO:0000313|EMBL:RSY18569.1}, DAH82_02990
GN {ECO:0000313|EMBL:RSY03600.1}, DAH83_14600
GN {ECO:0000313|EMBL:RSY04768.1}, DAH84_13635
GN {ECO:0000313|EMBL:RSX80788.1}, DAH85_00100
GN {ECO:0000313|EMBL:RSX96853.1}, DAH86_00485
GN {ECO:0000313|EMBL:RSX92505.1}, DAH87_03830
GN {ECO:0000313|EMBL:RSX98812.1}, DAH88_01050
GN {ECO:0000313|EMBL:RSX69821.1}, DAH89_01400
GN {ECO:0000313|EMBL:RSX77519.1}, DAH90_02100
GN {ECO:0000313|EMBL:RSX83023.1}, DAH91_01910
GN {ECO:0000313|EMBL:RSX66317.1}, DAH92_01405
GN {ECO:0000313|EMBL:RSX73487.1}, DAH93_01405
GN {ECO:0000313|EMBL:RSX48630.1}, DAH94_01395
GN {ECO:0000313|EMBL:RSX45711.1}, DAH95_01050
GN {ECO:0000313|EMBL:RSX40558.1}, DAH96_07865
GN {ECO:0000313|EMBL:RSX20712.1}, DAH97_07260
GN {ECO:0000313|EMBL:RSX33439.1}, DAH98_00445
GN {ECO:0000313|EMBL:RSX30965.1}, DAH99_03440
GN {ECO:0000313|EMBL:RSX31978.1}, DAI00_01400
GN {ECO:0000313|EMBL:RSX15491.1}, DAI01_09500
GN {ECO:0000313|EMBL:RSX07231.1};
OS Sphingomonas koreensis.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
OC Sphingomonadaceae; Sphingomonas.
OX NCBI_TaxID=93064 {ECO:0000313|EMBL:APR54834.1, ECO:0000313|Proteomes:UP000185161};
RN [1] {ECO:0000313|EMBL:APR54834.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=ABOJV {ECO:0000313|EMBL:APR54834.1};
RA Conlan S., Thomas P.J., Mullikin J., Palmore T.N., Frank K.M., Segre J.A.;
RT "Whole genome sequencing of Sphingomonas koreensis.";
RL Submitted (DEC-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000185161}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ABOJV {ECO:0000313|Proteomes:UP000185161};
RA Conlan S., Thomas P.J., Mullikin J., Palmore T.N., Frank K.M., Segre J.A.;
RT "Whole genome sequencing of Sphingomonas sp. ABOJV.";
RL Submitted (DEC-2016) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Proteomes:UP000286970, ECO:0000313|Proteomes:UP000287271}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SK-NIH.Env2_1116 {ECO:0000313|EMBL:RSU30958.1,
RC ECO:0000313|Proteomes:UP000286970}, SK-NIH.Env3_1116
RC {ECO:0000313|EMBL:RSU41349.1, ECO:0000313|Proteomes:UP000287271},
RC SK-NIH.Env4_1116 {ECO:0000313|EMBL:RSU23051.1,
RC ECO:0000313|Proteomes:UP000287347}, SK-NIH.Env8_1116
RC {ECO:0000313|EMBL:RSU32260.1, ECO:0000313|Proteomes:UP000287976},
RC SK-NIH.Pt2_0716 {ECO:0000313|EMBL:RSU45027.1,
RC ECO:0000313|Proteomes:UP000287307}, SK-NIH.Pt4_0816
RC {ECO:0000313|EMBL:RSU39500.1, ECO:0000313|Proteomes:UP000287414}, and
RC SK-NIH.Pt6_1016 {ECO:0000313|EMBL:RSU51495.1,
RC ECO:0000313|Proteomes:UP000287315};
RA Johnson R.C., Deming C., Conlan S., Zellmer C., Michelin A., Lee-Lin S.-Q.,
RA Thomas P.J., Park M., Weingarten R.A., Less J., Dekker J.P., Frank K.M.,
RA Musser K.A., Mcquiston J.R., Henderson D.K., Lau A.F., Palmore T.N.,
RA Segre J.A.;
RT "Genomic and Epidemiologic Investigation to Identify Sphingomonas koreensis
RT Point Sources in an Indolent Hospital Outbreak.";
RL Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases.
RN [4] {ECO:0000313|Proteomes:UP000286681, ECO:0000313|Proteomes:UP000286696}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KCTC 2882 {ECO:0000313|EMBL:RSU67278.1,
RC ECO:0000313|Proteomes:UP000286710}, KCTC 2883
RC {ECO:0000313|EMBL:RSU58913.1, ECO:0000313|Proteomes:UP000286956},
RC SK-NIH.Env10_0317 {ECO:0000313|EMBL:RSV08370.1,
RC ECO:0000313|Proteomes:UP000286681}, SK-NIH.Env11_0417
RC {ECO:0000313|EMBL:RSU84751.1, ECO:0000313|Proteomes:UP000287165},
RC SK-NIH.Env12_0417 {ECO:0000313|EMBL:RSU89531.1,
RC ECO:0000313|Proteomes:UP000288342}, SK-NIH.Env15_0417
RC {ECO:0000313|EMBL:RSU85856.1, ECO:0000313|Proteomes:UP000288648},
RC SK-NIH.Env1_1016 {ECO:0000313|EMBL:RSV58757.1,
RC ECO:0000313|Proteomes:UP000288283}, SK-NIH.Env5_1116
RC {ECO:0000313|EMBL:RSV61115.1, ECO:0000313|Proteomes:UP000287812},
RC SK-NIH.Env7_1116 {ECO:0000313|EMBL:RSX14817.1,
RC ECO:0000313|Proteomes:UP000288130}, SK-NIH.Env9_0217
RC {ECO:0000313|EMBL:RSU90998.1, ECO:0000313|Proteomes:UP000287377},
RC SK-NIH.Pt10_0210 {ECO:0000313|EMBL:RSV13065.1,
RC ECO:0000313|Proteomes:UP000288286}, SK-NIH.Pt11_0411
RC {ECO:0000313|EMBL:RSX03060.1, ECO:0000313|Proteomes:UP000288535},
RC SK-NIH.Pt12_0112 {ECO:0000313|EMBL:RSV60696.1,
RC ECO:0000313|Proteomes:UP000286696}, SK-NIH.Pt14_0612
RC {ECO:0000313|EMBL:RSV38590.1, ECO:0000313|Proteomes:UP000287457},
RC SK-NIH.Pt16_1112 {ECO:0000313|EMBL:RSV49065.1,
RC ECO:0000313|Proteomes:UP000287806}, SK-NIH.Pt7_0906
RC {ECO:0000313|EMBL:RSV28632.1, ECO:0000313|Proteomes:UP000288528},
RC SK-NIH.Pt8_0208 {ECO:0000313|EMBL:RSV31489.1,
RC ECO:0000313|Proteomes:UP000287886}, SK-NIH.Pt9_0208
RC {ECO:0000313|EMBL:RSV11136.1, ECO:0000313|Proteomes:UP000287793}, and
RC SK-NY1_0417 {ECO:0000313|EMBL:RSU99902.1,
RC ECO:0000313|Proteomes:UP000288253};
RA Johnson R.C., Deming C., Conlan S., Zellmer C.J., Michelin A.V.,
RA Lee-Lin S., Thomas P.J., Park M., Weingarten R.A., Less J., Dekker J.P.,
RA Frank K.M., Musser K.A., Mcquiston J.R., Henderson D.K., Lau A.F.,
RA Palmore T.N., Segre J.A.;
RT "Genomic and Epidemiologic Investigation of an Indolent Hospital
RT Outbreak.";
RL Submitted (JUL-2018) to the EMBL/GenBank/DDBJ databases.
RN [5] {ECO:0000313|Proteomes:UP000286706, ECO:0000313|Proteomes:UP000286739}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SK-NIH.Env13_0417 {ECO:0000313|EMBL:RSZ18253.1,
RC ECO:0000313|Proteomes:UP000287513}, SK-NIH.Env14_0417
RC {ECO:0000313|EMBL:RSZ02468.1, ECO:0000313|Proteomes:UP000288569},
RC SK-NIH.Env16_0517 {ECO:0000313|EMBL:RSZ16178.1,
RC ECO:0000313|Proteomes:UP000287015}, SK-NIH.Env17_0517
RC {ECO:0000313|EMBL:RSZ22381.1, ECO:0000313|Proteomes:UP000287799},
RC SK-NIH.Env18_0517 {ECO:0000313|EMBL:RSZ03651.1,
RC ECO:0000313|Proteomes:UP000288230}, SK-NIH.Env19_0617
RC {ECO:0000313|EMBL:RSY84552.1, ECO:0000313|Proteomes:UP000288258},
RC SK-NIH.Env20_0617 {ECO:0000313|EMBL:RSY88489.1,
RC ECO:0000313|Proteomes:UP000287482}, SK-NIH.Env21_0617
RC {ECO:0000313|EMBL:RSZ00628.1, ECO:0000313|Proteomes:UP000287363},
RC SK-NIH.Env22_0617 {ECO:0000313|EMBL:RSZ13575.1,
RC ECO:0000313|Proteomes:UP000287001}, SK-NIH.Env23_0717
RC {ECO:0000313|EMBL:RSY76187.1, ECO:0000313|Proteomes:UP000287360},
RC SK-NIH.Env24_0717 {ECO:0000313|EMBL:RSY75467.1,
RC ECO:0000313|Proteomes:UP000287229}, SK-NIH.Env25_0717
RC {ECO:0000313|EMBL:RSY64432.1, ECO:0000313|Proteomes:UP000288269},
RC SK-NIH.Env26_0717 {ECO:0000313|EMBL:RSY62998.1,
RC ECO:0000313|Proteomes:UP000287417}, SK-NIH.Env27_0717
RC {ECO:0000313|EMBL:RSY54447.1, ECO:0000313|Proteomes:UP000286788},
RC SK-NIH.Env28_0717 {ECO:0000313|EMBL:RSY77316.1,
RC ECO:0000313|Proteomes:UP000288630}, SK-NIH.Env29_0717
RC {ECO:0000313|EMBL:RSY38655.1, ECO:0000313|Proteomes:UP000287038},
RC SK-NIH.Env30_0717 {ECO:0000313|EMBL:RSY47406.1,
RC ECO:0000313|Proteomes:UP000288207}, SK-NIH.Env31_0717
RC {ECO:0000313|EMBL:RSY39128.1, ECO:0000313|Proteomes:UP000287340},
RC SK-NIH.Env32_0717 {ECO:0000313|EMBL:RSY51860.1,
RC ECO:0000313|Proteomes:UP000288007}, SK-NIH.Env33_0717
RC {ECO:0000313|EMBL:RSY28867.1, ECO:0000313|Proteomes:UP000287541},
RC SK-NIH.Env34_0717 {ECO:0000313|EMBL:RSY16117.1,
RC ECO:0000313|Proteomes:UP000288649}, SK-NIH.Env35_0717
RC {ECO:0000313|EMBL:RSY32234.1, ECO:0000313|Proteomes:UP000287968},
RC SK-NIH.Env36_0717 {ECO:0000313|EMBL:RSY03600.1,
RC ECO:0000313|Proteomes:UP000288516}, SK-NIH.Env37_0717
RC {ECO:0000313|EMBL:RSY24424.1, ECO:0000313|Proteomes:UP000287028},
RC SK-NIH.Env38_0817 {ECO:0000313|EMBL:RSY18569.1,
RC ECO:0000313|Proteomes:UP000287257}, SK-NIH.Env39_0817
RC {ECO:0000313|EMBL:RSY04768.1, ECO:0000313|Proteomes:UP000287073},
RC SK-NIH.Env40_0817 {ECO:0000313|EMBL:RSX80788.1,
RC ECO:0000313|Proteomes:UP000288050}, SK-NIH.Env41_0817
RC {ECO:0000313|EMBL:RSX96853.1, ECO:0000313|Proteomes:UP000286739},
RC SK-NIH.Env42_0817 {ECO:0000313|EMBL:RSX92505.1,
RC ECO:0000313|Proteomes:UP000288181}, SK-NIH.Env43_0817
RC {ECO:0000313|EMBL:RSX98812.1, ECO:0000313|Proteomes:UP000286795},
RC SK-NIH.Env44_0817 {ECO:0000313|EMBL:RSX69821.1,
RC ECO:0000313|Proteomes:UP000286792}, SK-NIH.Env45_1017
RC {ECO:0000313|EMBL:RSX77519.1, ECO:0000313|Proteomes:UP000286760},
RC SK-NIH.Env46_1017 {ECO:0000313|EMBL:RSX73487.1,
RC ECO:0000313|Proteomes:UP000287577}, SK-NIH.Env47_1017
RC {ECO:0000313|EMBL:RSX48630.1, ECO:0000313|Proteomes:UP000288581},
RC SK-NIH.Env48_1017 {ECO:0000313|EMBL:RSX83023.1,
RC ECO:0000313|Proteomes:UP000287090}, SK-NIH.Env49_1017
RC {ECO:0000313|EMBL:RSX66317.1, ECO:0000313|Proteomes:UP000286744},
RC SK-NIH.Env50_1017 {ECO:0000313|EMBL:RSX45711.1,
RC ECO:0000313|Proteomes:UP000288198}, SK-NIH.Env51_1017
RC {ECO:0000313|EMBL:RSX40558.1, ECO:0000313|Proteomes:UP000287844},
RC SK-NIH.Env52_1017 {ECO:0000313|EMBL:RSX20712.1,
RC ECO:0000313|Proteomes:UP000287083}, SK-NIH.Env53_1017
RC {ECO:0000313|EMBL:RSX33439.1, ECO:0000313|Proteomes:UP000288435},
RC SK-NIH.Env54_1217 {ECO:0000313|EMBL:RSX31978.1,
RC ECO:0000313|Proteomes:UP000288203}, SK-NIH.Env55_1217
RC {ECO:0000313|EMBL:RSX15491.1, ECO:0000313|Proteomes:UP000286706},
RC SK-NIH.Env56_1217 {ECO:0000313|EMBL:RSX07231.1,
RC ECO:0000313|Proteomes:UP000287020}, and SK-NIH.Env57_1217
RC {ECO:0000313|EMBL:RSX30965.1, ECO:0000313|Proteomes:UP000287236};
RA Johnson R.C., Deming C., Conlan S., Zellmer C.J., Michelin A.V.,
RA Lee-Lin S.-Q., Thomas P.J., Park M., Weingarten R.A., Less J., Dekker J.P.,
RA Frank K.M., Musser K.A., Mcquiston J.R., Henderson D.K., Lau A.F.,
RA Palmore T.N., Segre J.A.;
RT "Genomic and Epidemiologic Investigation of an Indolent Hospital
RT Outbreak.";
RL Submitted (JUL-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Catalyzes the hydrolysis of 10-formyltetrahydrofolate
CC (formyl-FH4) to formate and tetrahydrofolate (FH4). {ECO:0000256|HAMAP-
CC Rule:MF_01927}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=(6R)-10-formyltetrahydrofolate + H2O = (6S)-5,6,7,8-
CC tetrahydrofolate + formate + H(+); Xref=Rhea:RHEA:19833,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:15740,
CC ChEBI:CHEBI:57453, ChEBI:CHEBI:195366; EC=3.5.1.10;
CC Evidence={ECO:0000256|HAMAP-Rule:MF_01927};
CC -!- PATHWAY: Purine metabolism; IMP biosynthesis via de novo pathway;
CC formate from 10-formyl-5,6,7,8-tetrahydrofolate: step 1/1.
CC {ECO:0000256|HAMAP-Rule:MF_01927}.
CC -!- SIMILARITY: Belongs to the PurU family. {ECO:0000256|HAMAP-
CC Rule:MF_01927}.
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DR EMBL; CP018820; APR54834.1; -; Genomic_DNA.
DR EMBL; QLJD01000002; RSU23051.1; -; Genomic_DNA.
DR EMBL; QLJF01000001; RSU30958.1; -; Genomic_DNA.
DR EMBL; QLJC01000001; RSU32260.1; -; Genomic_DNA.
DR EMBL; QLJI01000001; RSU39500.1; -; Genomic_DNA.
DR EMBL; QLJE01000003; RSU41349.1; -; Genomic_DNA.
DR EMBL; QLJJ01000001; RSU45027.1; -; Genomic_DNA.
DR EMBL; QLJG01000004; RSU51495.1; -; Genomic_DNA.
DR EMBL; QQWJ01000013; RSU58913.1; -; Genomic_DNA.
DR EMBL; QQWK01000012; RSU67278.1; -; Genomic_DNA.
DR EMBL; QQWL01000002; RSU84751.1; -; Genomic_DNA.
DR EMBL; QQWM01000001; RSU85856.1; -; Genomic_DNA.
DR EMBL; QQWN01000030; RSU89531.1; -; Genomic_DNA.
DR EMBL; QQWQ01000002; RSU90998.1; -; Genomic_DNA.
DR EMBL; QQWP01000001; RSU99902.1; -; Genomic_DNA.
DR EMBL; QQWO01000001; RSV08370.1; -; Genomic_DNA.
DR EMBL; QQWS01000001; RSV11136.1; -; Genomic_DNA.
DR EMBL; QQWR01000001; RSV13065.1; -; Genomic_DNA.
DR EMBL; QQWU01000001; RSV28632.1; -; Genomic_DNA.
DR EMBL; QQWT01000001; RSV31489.1; -; Genomic_DNA.
DR EMBL; QQXA01000002; RSV38590.1; -; Genomic_DNA.
DR EMBL; QQXB01000002; RSV49065.1; -; Genomic_DNA.
DR EMBL; QQXG01000017; RSV58757.1; -; Genomic_DNA.
DR EMBL; QQXD01000002; RSV60696.1; -; Genomic_DNA.
DR EMBL; QQXE01000002; RSV61115.1; -; Genomic_DNA.
DR EMBL; QQXC01000001; RSX03060.1; -; Genomic_DNA.
DR EMBL; QQXQ01000005; RSX07231.1; -; Genomic_DNA.
DR EMBL; QQXF01000003; RSX14817.1; -; Genomic_DNA.
DR EMBL; QQXR01000001; RSX15491.1; -; Genomic_DNA.
DR EMBL; QQXV01000003; RSX20712.1; -; Genomic_DNA.
DR EMBL; QQXT01000001; RSX30965.1; -; Genomic_DNA.
DR EMBL; QQXS01000002; RSX31978.1; -; Genomic_DNA.
DR EMBL; QQXU01000003; RSX33439.1; -; Genomic_DNA.
DR EMBL; QQXW01000001; RSX40558.1; -; Genomic_DNA.
DR EMBL; QQXX01000001; RSX45711.1; -; Genomic_DNA.
DR EMBL; QQXY01000001; RSX48630.1; -; Genomic_DNA.
DR EMBL; QQYA01000001; RSX66317.1; -; Genomic_DNA.
DR EMBL; QQYD01000001; RSX69821.1; -; Genomic_DNA.
DR EMBL; QQXZ01000001; RSX73487.1; -; Genomic_DNA.
DR EMBL; QQYC01000001; RSX77519.1; -; Genomic_DNA.
DR EMBL; QQYH01000012; RSX80788.1; -; Genomic_DNA.
DR EMBL; QQYB01000001; RSX83023.1; -; Genomic_DNA.
DR EMBL; QQYF01000001; RSX92505.1; -; Genomic_DNA.
DR EMBL; QQYG01000001; RSX96853.1; -; Genomic_DNA.
DR EMBL; QQYE01000002; RSX98812.1; -; Genomic_DNA.
DR EMBL; QQYJ01000002; RSY03600.1; -; Genomic_DNA.
DR EMBL; QQYI01000013; RSY04768.1; -; Genomic_DNA.
DR EMBL; QQYN01000001; RSY16117.1; -; Genomic_DNA.
DR EMBL; QQYK01000001; RSY18569.1; -; Genomic_DNA.
DR EMBL; QQYL01000002; RSY24424.1; -; Genomic_DNA.
DR EMBL; QQYO01000001; RSY28867.1; -; Genomic_DNA.
DR EMBL; QQYM01000001; RSY32234.1; -; Genomic_DNA.
DR EMBL; QQYS01000001; RSY38655.1; -; Genomic_DNA.
DR EMBL; QQYQ01000006; RSY39128.1; -; Genomic_DNA.
DR EMBL; QQYR01000002; RSY47406.1; -; Genomic_DNA.
DR EMBL; QQYP01000001; RSY51860.1; -; Genomic_DNA.
DR EMBL; QQYU01000004; RSY54447.1; -; Genomic_DNA.
DR EMBL; QQYV01000002; RSY62998.1; -; Genomic_DNA.
DR EMBL; QQYW01000001; RSY64432.1; -; Genomic_DNA.
DR EMBL; QQYX01000001; RSY75467.1; -; Genomic_DNA.
DR EMBL; QQYY01000001; RSY76187.1; -; Genomic_DNA.
DR EMBL; QQYT01000001; RSY77316.1; -; Genomic_DNA.
DR EMBL; QQZB01000003; RSY84552.1; -; Genomic_DNA.
DR EMBL; QQZA01000003; RSY88489.1; -; Genomic_DNA.
DR EMBL; QQZD01000001; RSZ00628.1; -; Genomic_DNA.
DR EMBL; QQZG01000002; RSZ02468.1; -; Genomic_DNA.
DR EMBL; QQZE01000002; RSZ03651.1; -; Genomic_DNA.
DR EMBL; QQZC01000002; RSZ13575.1; -; Genomic_DNA.
DR EMBL; QQZF01000001; RSZ16178.1; -; Genomic_DNA.
DR EMBL; QQZH01000001; RSZ18253.1; -; Genomic_DNA.
DR EMBL; QQZI01000001; RSZ22381.1; -; Genomic_DNA.
DR STRING; 93064.BRX40_05525; -.
DR KEGG; skr:BRX40_05525; -.
DR OrthoDB; 9806170at2; -.
DR UniPathway; UPA00074; UER00170.
DR Proteomes; UP000185161; Chromosome.
DR Proteomes; UP000286681; Unassembled WGS sequence.
DR Proteomes; UP000286696; Unassembled WGS sequence.
DR Proteomes; UP000286706; Unassembled WGS sequence.
DR Proteomes; UP000286710; Unassembled WGS sequence.
DR Proteomes; UP000286739; Unassembled WGS sequence.
DR Proteomes; UP000286744; Unassembled WGS sequence.
DR Proteomes; UP000286760; Unassembled WGS sequence.
DR Proteomes; UP000286788; Unassembled WGS sequence.
DR Proteomes; UP000286792; Unassembled WGS sequence.
DR Proteomes; UP000286795; Unassembled WGS sequence.
DR Proteomes; UP000286956; Unassembled WGS sequence.
DR Proteomes; UP000286970; Unassembled WGS sequence.
DR Proteomes; UP000287001; Unassembled WGS sequence.
DR Proteomes; UP000287015; Unassembled WGS sequence.
DR Proteomes; UP000287020; Unassembled WGS sequence.
DR Proteomes; UP000287028; Unassembled WGS sequence.
DR Proteomes; UP000287038; Unassembled WGS sequence.
DR Proteomes; UP000287073; Unassembled WGS sequence.
DR Proteomes; UP000287083; Unassembled WGS sequence.
DR Proteomes; UP000287090; Unassembled WGS sequence.
DR Proteomes; UP000287165; Unassembled WGS sequence.
DR Proteomes; UP000287229; Unassembled WGS sequence.
DR Proteomes; UP000287236; Unassembled WGS sequence.
DR Proteomes; UP000287257; Unassembled WGS sequence.
DR Proteomes; UP000287271; Unassembled WGS sequence.
DR Proteomes; UP000287307; Unassembled WGS sequence.
DR Proteomes; UP000287315; Unassembled WGS sequence.
DR Proteomes; UP000287340; Unassembled WGS sequence.
DR Proteomes; UP000287347; Unassembled WGS sequence.
DR Proteomes; UP000287360; Unassembled WGS sequence.
DR Proteomes; UP000287363; Unassembled WGS sequence.
DR Proteomes; UP000287377; Unassembled WGS sequence.
DR Proteomes; UP000287414; Unassembled WGS sequence.
DR Proteomes; UP000287417; Unassembled WGS sequence.
DR Proteomes; UP000287457; Unassembled WGS sequence.
DR Proteomes; UP000287482; Unassembled WGS sequence.
DR Proteomes; UP000287513; Unassembled WGS sequence.
DR Proteomes; UP000287541; Unassembled WGS sequence.
DR Proteomes; UP000287577; Unassembled WGS sequence.
DR Proteomes; UP000287793; Unassembled WGS sequence.
DR Proteomes; UP000287799; Unassembled WGS sequence.
DR Proteomes; UP000287806; Unassembled WGS sequence.
DR Proteomes; UP000287812; Unassembled WGS sequence.
DR Proteomes; UP000287844; Unassembled WGS sequence.
DR Proteomes; UP000287886; Unassembled WGS sequence.
DR Proteomes; UP000287968; Unassembled WGS sequence.
DR Proteomes; UP000287976; Unassembled WGS sequence.
DR Proteomes; UP000288007; Unassembled WGS sequence.
DR Proteomes; UP000288050; Unassembled WGS sequence.
DR Proteomes; UP000288130; Unassembled WGS sequence.
DR Proteomes; UP000288181; Unassembled WGS sequence.
DR Proteomes; UP000288198; Unassembled WGS sequence.
DR Proteomes; UP000288203; Unassembled WGS sequence.
DR Proteomes; UP000288207; Unassembled WGS sequence.
DR Proteomes; UP000288230; Unassembled WGS sequence.
DR Proteomes; UP000288253; Unassembled WGS sequence.
DR Proteomes; UP000288258; Unassembled WGS sequence.
DR Proteomes; UP000288269; Unassembled WGS sequence.
DR Proteomes; UP000288283; Unassembled WGS sequence.
DR Proteomes; UP000288286; Unassembled WGS sequence.
DR Proteomes; UP000288342; Unassembled WGS sequence.
DR Proteomes; UP000288435; Unassembled WGS sequence.
DR Proteomes; UP000288516; Unassembled WGS sequence.
DR Proteomes; UP000288528; Unassembled WGS sequence.
DR Proteomes; UP000288535; Unassembled WGS sequence.
DR Proteomes; UP000288569; Unassembled WGS sequence.
DR Proteomes; UP000288581; Unassembled WGS sequence.
DR Proteomes; UP000288630; Unassembled WGS sequence.
DR Proteomes; UP000288648; Unassembled WGS sequence.
DR Proteomes; UP000288649; Unassembled WGS sequence.
DR GO; GO:0008864; F:formyltetrahydrofolate deformylase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006189; P:'de novo' IMP biosynthetic process; IEA:UniProtKB-UniRule.
DR GO; GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
DR CDD; cd04875; ACT_F4HF-DF; 1.
DR CDD; cd08648; FMT_core_Formyl-FH4-Hydrolase_C; 1.
DR Gene3D; 3.30.70.260; -; 1.
DR Gene3D; 3.40.50.170; Formyl transferase, N-terminal domain; 1.
DR HAMAP; MF_01927; PurU; 1.
DR InterPro; IPR045865; ACT-like_dom_sf.
DR InterPro; IPR002912; ACT_dom.
DR InterPro; IPR041729; Formyl-FH4-Hydrolase_C.
DR InterPro; IPR002376; Formyl_transf_N.
DR InterPro; IPR036477; Formyl_transf_N_sf.
DR InterPro; IPR004810; PurU.
DR InterPro; IPR044074; PurU_ACT.
DR NCBIfam; TIGR00655; PurU; 1.
DR PANTHER; PTHR42706; FORMYLTETRAHYDROFOLATE DEFORMYLASE; 1.
DR PANTHER; PTHR42706:SF1; FORMYLTETRAHYDROFOLATE DEFORMYLASE 1, MITOCHONDRIAL; 1.
DR Pfam; PF00551; Formyl_trans_N; 1.
DR PIRSF; PIRSF036480; FormyFH4_hydr; 1.
DR PRINTS; PR01575; FFH4HYDRLASE.
DR SUPFAM; SSF55021; ACT-like; 1.
DR SUPFAM; SSF53328; Formyltransferase; 1.
DR PROSITE; PS51671; ACT; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|HAMAP-Rule:MF_01927};
KW One-carbon metabolism {ECO:0000256|ARBA:ARBA00022563, ECO:0000256|HAMAP-
KW Rule:MF_01927}; Purine biosynthesis {ECO:0000256|HAMAP-Rule:MF_01927};
KW Reference proteome {ECO:0000313|Proteomes:UP000185161}.
FT DOMAIN 1..81
FT /note="ACT"
FT /evidence="ECO:0000259|PROSITE:PS51671"
FT ACT_SITE 225
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01927"
SQ SEQUENCE 281 AA; 30883 MW; 6DB433BC6E846C3E CRC64;
MLTLTCVDRV GIVAGVTGFL ARNDGFILDS QQYADLETGR FFMRVVFTAG GPGFPEGRDA
LVSAFLPVAA EFELDWGLSA SDEKPRLVVA VSKGSHCLND LLHRQQSGTL SAQIVAVVSN
HDRLRSLTEW HGVPYHHLPV GEGGNAEQER AIEAVMEEAA APYLILARYM QVLTPAFADR
LAGRCVNIHH SFLPGFKGAR PYHRAHERGV KLIGATAHFV TSDLDEGPII EQAVERVDHR
DSVDDLIRIG RDIEAQVLAR AVDALGERRL FLNGNRTLVF R
//
