ID A0A1L7CI09_9CORY Unreviewed; 399 AA.
AC A0A1L7CI09;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=Probable acetyl-CoA acetyltransferase {ECO:0000256|ARBA:ARBA00040529};
DE EC=2.3.1.9 {ECO:0000256|ARBA:ARBA00012705};
GN ORFNames=CAQU_10480 {ECO:0000313|EMBL:APT85403.1};
OS Corynebacterium aquilae DSM 44791.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales;
OC Corynebacteriaceae; Corynebacterium.
OX NCBI_TaxID=1431546 {ECO:0000313|EMBL:APT85403.1, ECO:0000313|Proteomes:UP000185478};
RN [1] {ECO:0000313|EMBL:APT85403.1, ECO:0000313|Proteomes:UP000185478}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=S-613 {ECO:0000313|EMBL:APT85403.1,
RC ECO:0000313|Proteomes:UP000185478};
RA Ruckert C., Albersmeier A., Winkler A., Kalinowski J.;
RT "Complete genome sequence of Corynebacterium aquilae S-613T(T) (=DSM
RT 44791(T)), isolated from the choana of a healthy golden eagle.";
RL Submitted (AUG-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the thiolase-like superfamily. Thiolase family.
CC {ECO:0000256|ARBA:ARBA00010982, ECO:0000256|RuleBase:RU003557}.
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DR EMBL; CP009245; APT85403.1; -; Genomic_DNA.
DR RefSeq; WP_075727426.1; NZ_CP009245.1.
DR AlphaFoldDB; A0A1L7CI09; -.
DR STRING; 1431546.CAQU_10480; -.
DR KEGG; caqu:CAQU_10480; -.
DR OrthoDB; 4475716at2; -.
DR Proteomes; UP000185478; Chromosome.
DR GO; GO:0003985; F:acetyl-CoA C-acetyltransferase activity; IEA:UniProtKB-EC.
DR CDD; cd00751; thiolase; 1.
DR Gene3D; 3.40.47.10; -; 2.
DR InterPro; IPR002155; Thiolase.
DR InterPro; IPR016039; Thiolase-like.
DR InterPro; IPR020615; Thiolase_acyl_enz_int_AS.
DR InterPro; IPR020610; Thiolase_AS.
DR InterPro; IPR020617; Thiolase_C.
DR InterPro; IPR020613; Thiolase_CS.
DR InterPro; IPR020616; Thiolase_N.
DR NCBIfam; TIGR01930; AcCoA-C-Actrans; 1.
DR PANTHER; PTHR18919; ACETYL-COA C-ACYLTRANSFERASE; 1.
DR PANTHER; PTHR18919:SF153; TRIFUNCTIONAL ENZYME SUBUNIT BETA, MITOCHONDRIAL; 1.
DR Pfam; PF02803; Thiolase_C; 1.
DR Pfam; PF00108; Thiolase_N; 1.
DR PIRSF; PIRSF000429; Ac-CoA_Ac_transf; 1.
DR SUPFAM; SSF53901; Thiolase-like; 2.
DR PROSITE; PS00098; THIOLASE_1; 1.
DR PROSITE; PS00737; THIOLASE_2; 1.
DR PROSITE; PS00099; THIOLASE_3; 1.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000256|RuleBase:RU003557,
KW ECO:0000313|EMBL:APT85403.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000185478};
KW Transferase {ECO:0000256|RuleBase:RU003557, ECO:0000313|EMBL:APT85403.1}.
FT DOMAIN 11..268
FT /note="Thiolase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00108"
FT DOMAIN 278..397
FT /note="Thiolase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02803"
FT ACT_SITE 95
FT /note="Acyl-thioester intermediate"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
FT ACT_SITE 355
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
FT ACT_SITE 385
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
SQ SEQUENCE 399 AA; 40858 MW; F28000C8D511735E CRC64;
MANPQHTPDD IVIVGAARTP TGRFLGGLSS LPATALGAIA IKGALEQAGV NPDRVDAVVF
GQVLQAGAGQ NPTKQAALGA GVPQRAHTNT VNKVCLSGLT AIIDGSRMLK VGDAEVVVAG
GMESMSNAPH LLSNSRTGTR YGAATMKDHM ESDGLTCARL GISMGELTET HADRYPVTRQ
EQDSLALHSH QAAHDAWEDG TFDREVVPVT VSTRKGETVV SRDEGIRAGL SQQDLDKLSP
AFVKDGSITV AHASQISDGA SAVVLTRRGT AQDNGWPVLA TVCAAGQVAG PDSSLQAQPA
NAIEQALARQ GWSAAELDHV EINEAFADVV IHSARQLGVD MSTVNPAGGA LALGHPIGAS
GARLVVHAAH RIAAGKSHRA AVGLCGGGGQ GEALLLEDA
//
