ID A0A1L7CPZ9_CORFL Unreviewed; 615 AA.
AC A0A1L7CPZ9;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=3-hydroxybenzoate 4-monooxygenase {ECO:0000313|EMBL:KAA8719548.1};
DE SubName: Full=Phenol 2-monooxygenase {ECO:0000313|EMBL:APT87924.1};
DE EC=1.14.13.7 {ECO:0000313|EMBL:APT87924.1};
GN ORFNames=CFLV_12715 {ECO:0000313|EMBL:APT87924.1}, F4V60_12220
GN {ECO:0000313|EMBL:KAA8719548.1};
OS Corynebacterium flavescens.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales;
OC Corynebacteriaceae; Corynebacterium.
OX NCBI_TaxID=28028 {ECO:0000313|EMBL:APT87924.1, ECO:0000313|Proteomes:UP000185479};
RN [1] {ECO:0000313|EMBL:APT87924.1, ECO:0000313|Proteomes:UP000185479}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=OJ8 {ECO:0000313|EMBL:APT87924.1,
RC ECO:0000313|Proteomes:UP000185479};
RA Ruckert C., Albersmeier A., Winkler A., Kalinowski J.;
RT "Complete genome sequence of Corynebacterium flavescens OJ8(T)(=DSM
RT 20296(T)), isolated from cheese.";
RL Submitted (AUG-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:KAA8719548.1, ECO:0000313|Proteomes:UP000322697}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CCUG 28791T {ECO:0000313|EMBL:KAA8719548.1,
RC ECO:0000313|Proteomes:UP000322697};
RA Pineiro-Iglesias B., Tunovic T., Unosson C., Inganas E., Ohlen M.,
RA Cardew S., Jensie-Markopoulos S., Salva-Serra F., Jaen-Luchoro D.,
RA Karlsson R., Svensson-Stadler L., Chun J., Moore E.;
RT "Draft genome sequence of various Type strains from the CCUG.";
RL Submitted (SEP-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974};
CC -!- SIMILARITY: Belongs to the PheA/TfdB FAD monooxygenase family.
CC {ECO:0000256|ARBA:ARBA00007801}.
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DR EMBL; CP009246; APT87924.1; -; Genomic_DNA.
DR EMBL; VXKK01000046; KAA8719548.1; -; Genomic_DNA.
DR RefSeq; WP_075730852.1; NZ_VXKK01000046.1.
DR AlphaFoldDB; A0A1L7CPZ9; -.
DR STRING; 28028.CFLV_12715; -.
DR GeneID; 82881523; -.
DR KEGG; cfc:CFLV_12715; -.
DR OrthoDB; 8670884at2; -.
DR Proteomes; UP000185479; Chromosome.
DR Proteomes; UP000322697; Unassembled WGS sequence.
DR GO; GO:0071949; F:FAD binding; IEA:InterPro.
DR GO; GO:0018662; F:phenol 2-monooxygenase activity; IEA:UniProtKB-EC.
DR CDD; cd02979; PHOX_C; 1.
DR Gene3D; 3.40.30.20; -; 1.
DR Gene3D; 3.30.9.10; D-Amino Acid Oxidase, subunit A, domain 2; 1.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR InterPro; IPR002938; FAD-bd.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR012941; Phe_hydrox_C_dim_dom.
DR InterPro; IPR038220; PHOX_C_sf.
DR InterPro; IPR036249; Thioredoxin-like_sf.
DR PANTHER; PTHR43004:SF6; FAD_NAD(P)-BINDING OXIDOREDUCTASE FAMILY PROTEIN; 1.
DR PANTHER; PTHR43004; TRK SYSTEM POTASSIUM UPTAKE PROTEIN; 1.
DR Pfam; PF01494; FAD_binding_3; 1.
DR Pfam; PF07976; Phe_hydrox_dim; 1.
DR PRINTS; PR00420; RNGMNOXGNASE.
DR SUPFAM; SSF54373; FAD-linked reductases, C-terminal domain; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR SUPFAM; SSF52833; Thioredoxin-like; 1.
PE 3: Inferred from homology;
KW Monooxygenase {ECO:0000313|EMBL:APT87924.1};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000313|EMBL:APT87924.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000185479}.
FT DOMAIN 33..391
FT /note="FAD-binding"
FT /evidence="ECO:0000259|Pfam:PF01494"
FT DOMAIN 423..580
FT /note="Phenol hydroxylase C-terminal dimerisation"
FT /evidence="ECO:0000259|Pfam:PF07976"
SQ SEQUENCE 615 AA; 68361 MW; 0A841342BC059F47 CRC64;
MQFHHNGYVS HDPRELAAAG YGIDRPIELP EKMDVLIVGS GPAGMVTAAQ LAMFPDINTR
IIESRPHRLE LGQADGIQSR SVETFQAFGF AKEIEEEAYE ITEMAFWNPD PENRNHIKRG
ATPVDDESGI SEFPHLIVNQ ARVLDYFARF ARRGPARITP DYGWSFISLE VGEGEYPVKA
VVEDGNGNTR ELEAKYVVGC DGARSQVRKS IGGKLQGDQA NHAWGVMDVV VDTDFPDWRT
KCAIHSRAGS ILHIPREGGY LCRVYVDLGV VPAGDGGAIR STPIERIIEK ANEIYSPYFI
DVKMVAWHSV YEVGHRLVES FADDGDSPRV FLTGDACHTH SAKAGQGMNV SMQDGFNLGW
KLGHVLSGRA PEQLLCTYHL ERQPAALNLI NFDRMWSTLM ATPPEELEDP GAVEKFYVAA
EEFAAGMMTE YEANMVVGDR RHQDLATGYP VGKRFKSFEV LRRCDAYPLH LGHQHSADGR
YRIYAFADSA TPADPSAMDS WAEQVGDILA SYAPQGLDEN AFFDVKAIYQ TTDHRQYSVL
DAPRLFRPVN GSLQVPNWEN VFNALPGEGD IFQARGISRE GAVVIVRPDQ YVGAVLRLDE
PAAVDEYFSR ALFKR
//
